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Gene therapy for Alzheimer's disease shows promise

In the first clinical trial of gene therapy for Alzheimer's disease researchers have produced preliminary evidence that gene therapy may slow the decline in mental functioning associated with Alzheimer's disease.

25 Apr 2005

New drug combo helps prevent strokes

A British research team at St. George's Hospital Medical School in London, have found that the addition of the anti-clotting drug Plavix to daily doses of aspirin helps prevent the risk of later strokes better than using aspirin alone.

25 Apr 2005

Simple actions could wipe out heart risks for Asian diabetics

New research, to be revealed on Tuesday 26th of April at the launch of the University of Warwick Medical School's new Clinical Sciences Research Institute at the University Hospital campus at Walsgrave in Coventry, has shown that very simple interventions to target the health care of UK Asian diabetics can almost wipe out the 40% higher risks of heart disease linked to diabetes in that community.

25 Apr 2005

Important new finding about the brain and its stem cells

A family's bravery and generosity in the face of their son's death three years ago has enabled researchers to make an important new finding about the brain and its stem cells.

25 Apr 2005

Risk scores may identify young individuals with atherosclerosis

Young people with atherosclerotic lesions may be identified by a risk score calculated from coronary heart disease factors like obesity, sex, age, cholesterol, and smoking, according to an article in the April 25 issue of Archives of Internal Medicine.

25 Apr 2005

Pattern of gene expression predicts multiple drug resistance, treatment failure in pediatric leukemia

The discovery of a specific pattern of gene expression linked to multiple-drug resistance of leukemic cells is giving researchers crucial information into why standard therapies fail to cure some children with acute lymphoblastic leukemia (ALL). This finding, from investigators at St. Jude Children’s Research Hospital, could lead to development of drugs that would overcome that resistance.

24 Apr 2005

Increasing benefit seen in novel drug AMN107, that treats Gleevec resistance

An investigational drug is producing powerful responses in patients resistant to Gleevec, the targeted therapy that helps most people diagnosed with chronic myeloid leukemia (CML), an international research team headed by investigators at The University of Texas M. D. Anderson Cancer Center is reporting.

23 Apr 2005

Smad7 protein levels may predict prostate cancer therapy response

Levels of the Smad7 protein may predict therapeutic response in patients with prostate cancer according to research published by investigators at the Uppsala Branch of the Ludwig Institute for Cancer Research (LICR).

23 Apr 2005

Testing new manic depression drugs in slime mould

Research by University College London (UCL) scientists could lead to the development of more effective drugs for treating manic depression thanks to a new screening approach developed in a "slime mould" - a microbe that lives in leaves and dung on forest floors.

23 Apr 2005

Drinking wine or beer has same result: higher blood pressure

Whether the drink of choice is a frosty beer or a full-bodied red wine, the effect is the same – higher blood pressure, according to research reported in Hypertension: Journal of the American Heart Association.

23 Apr 2005

Enlarged waist + elevated triglycerides = heart, stroke risks for women

A tape measure and a simple blood test may be the best way to gauge cardiovascular risk for postmenopausal women, according to a report published today in an obesity-themed issue of Circulation: Journal of the American Heart Association.

23 Apr 2005

Obesity sends Type 2 diabetes rates in children soaring

Research results revealed at the Diabetes UK Annual Professional Conference, show 22 children under 16 have Type 2 diabetes in East London alone. Past estimates suggest there were only around 100 children diagnosed with Type 2 diabetes in the UK but this figure now appears to be a vast underestimate.

23 Apr 2005

Canadian Diabetes Association, UBC partner on funding for childhood diabetes research

A new partnership announced by the Canadian Diabetes Association and the University of British Columbia (UBC) will help fund research in childhood diabetes. Not only will this research further investigate type 1 diabetes, it will also explore the areas of type 2 diabetes and obesity in children, a problem of growing concern and proportions.

23 Apr 2005

Demoralization: A syndrome which should not be confused with depression

A group of Italian researchers headed by Prof. Giovanni Fava (University of Bologna) has published a multicenter investigation on demoralization in the setting of medical disease. Demoralization was defined according to diagnostic criteria encompassing unpleasant, distressing feelings of personal failure and inadequacies, with a loss of continuity in the sense of sequence between past and future.

23 Apr 2005

Do psychotropic drugs cure mental disease?

Joanna Moncrieff (University College of London and David Cohen (Florida International University) discuss what is the actual role of psychotropic drugs as to mental disease in the May-June issue of Psychotherapy and Psychosomatics.

23 Apr 2005

Phobias and panic can be treated with internet-guided self-help

A group of researchers of the Imperial College of London headed by Professor Isaac Marks has published a randomized controlled study on internet-guided self-help for phobias and panic in the May-June issue of Psychotherapy and Psychosomatics.

23 Apr 2005

Do life events precede the onset of heart attacks?

A group of researchers of the University of Bologna (headed by Dr Chiara Rafanelli) has verified in a controlled study whether heart attacks are preceded by stressful life circumstances.

23 Apr 2005

Could diabetes drug prevent cancer?

A well known drug which is commonly used to treat Type 2 diabetes may prevent cancer tumours, according to researchers at the University of Dundee.

23 Apr 2005

Stem cells from adults may cause cancer

Stem cells, often lauded as future cures for numerous diseases, are immature "master" cells that can be programmed to become many kinds of tissue, but experts have known for a long time that stem cells harvested from embryos can turn cancerous and have been linked to leukaemias and breast cancer.

23 Apr 2005

Nanoparticles reveal tiny cancerous tumors

Specially designed nanoparticles can reveal tiny cancerous tumors that are invisible by ordinary means of detection, according to a study by researchers at Washington University School of Medicine in St. Louis.

22 Apr 2005