Gene News and Research

Latest Gene News and Research

Researcher identifies mechanisms that may cause resistance to BRAF inhibitor

BRAF mutation occurs in between 40% and 50% of metastasising melanomas (skin cancers), boosting tumour growth.

29 Aug 2016

Is the virtual gene panel the way forward asks Congenica at Dx Summit

Although the current practice of analysing defined gene panels for a specific disease has great utility, it is of limited benefit when a condition is not well defined.

29 Aug 2016

NEJM publishes MINDACT trial results

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, announces the peer-reviewed publication of the primary outcome results of the Microarray In Node-negative and 1 to 3 positive lymph node Disease may Avoid ChemoTherapy (MINDACT) clinical trial in the prestigious New England Journal of Medicine (NEJM). (i, iii, iv) The publication demonstrates that 46% of breast cancer patients considered for chemotherapy, whose tumors are classified MammaPrint Low Risk, have excellent survival without chemotherapy, and can thus be candidates to avoid this toxic therapy.

29 Aug 2016

NanoScope awarded AGI Grant to re-sensitize photo-degenerated retinal areas with MCO

Millions of individuals affected by Retinitis Pigmentosa (RP) are visually impaired due to photo-degeneration of retina. The visual loss starts with the peripheral region progressing towards the center leading to tunnel vision. Currently, there is no cure to restore vision in these patients. The disease leads not only to physical impairment, but has a significant emotional and psychological impact on quality of life of patients as well as their family members.

27 Aug 2016

Basic cell biology research into neurodegeneration may fuel understanding of neurodegenerative diseases

Clinical trials and translational medicine have certainly given people hope and rapid pathways to cures for some of mankind's most troublesome diseases, but now is not the time to overlook the power of basic research, says UC Santa Barbara neuroscientist Kenneth S. Kosik.

27 Aug 2016

Study suggests microRNAs may connect inflammation with heart disease risk in obese people

Inflammation likely plays a role in the increased risk of heart disease that comes with obesity, but scientists don't fully understand how obesity leads to heart disease.

26 Aug 2016

Researchers explore molecular mechanisms through which lead exposure may affect neural stem cells

Researchers have identified a potential molecular mechanism through which lead, a pervasive environmental toxin, may harm neural stem cells and neurodevelopment in children.

26 Aug 2016

SSRI treatment improves cognitive and social functioning in young children with fragile X

Treatment with sertraline may provide nominal but important improvements in cognition and social participation in very young children with fragile X syndrome, the most common genetic cause of intellectual disability and the leading single-gene cause of autism, a study by researchers with the UC Davis MIND Institute has found.

26 Aug 2016

Kobe University researchers develop new technique for high-level genome editing operation

A team involving Kobe University researchers has succeeded in developing 'Target-AID', a genome editing technique that does not cleave the DNA.

26 Aug 2016

Naturally-occurring sugars in woman's breast milk may protect infants against life threatening bacteria

A type of sugar found naturally in some women's breast milk may protect newborn babies from infection with a potentially life threatening bacterium called Group B streptococcus, according to a new study from Imperial College London.

26 Aug 2016

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

A team including the National Cancer Center, the RIKEN Center for Life Science Technologies , and Carna Biosciences Inc., has jointly announced the development of a novel small-molecule Wnt inhibitor named NCB-0846.

26 Aug 2016

Study reveals how pluripotency differs among mice, monkeys, and humans

Not too shabby, humans. New research shows that certain primate stem cells have pluripotency superior to some types derived from mice.

26 Aug 2016

Gene fusions in esophageal adenocarcinomas offer new molecular insights into lethal cancer

Despite years of research, cellular mechanisms contributing to cancers like esophageal adenocarcinoma have remained elusive.

26 Aug 2016

Research findings point to potential drug targets to improve angiogenesis in diabetes patients

Diabetes heightens the risk of vascular damage to heart and limbs, and impairs the ability to repair damage with new growth of blood vessels, called angiogenesis.

26 Aug 2016

Breakthrough in cancer cell screening advances personalised treatment of childhood leukaemia

Researchers at Newcastle University have been able to accurately predict how children whose cancer returns after treatment for leukaemia are likely to respond to further treatment.

26 Aug 2016

New findings into the biology of progressive hearing loss

New research with funding from UK charity Action on Hearing Loss has led to the discovery of a new biological mechanism involved in the progressive loss of hearing which could lead to new approaches to treating this common form of hearing loss.

26 Aug 2016

UCSF researchers identify new strategy to cultivate beneficial energy-burning fat

UC San Francisco researchers studying beige fat — a calorie-burning tissue that can help to ward off obesity and diabetes — have discovered a new strategy to cultivate this beneficial blubber.

25 Aug 2016

New study looks to saliva of humans and primates to gain insights into evolution

There's no need to reinvent the genetic wheel. That's one lesson of a new study that looks to the saliva of humans, gorillas, orangutans, macaques and African green monkeys for insights into evolution.

25 Aug 2016

Research findings pave way to effective strategies for treatment of visceral leishmaniasis

A study shows that stimulating the production of interleukin-17A (IL-17A), one of the cytokines released by cells of the immune system, can be an effective strategy for the treatment of visceral leishmaniasis, considered one of the six most important parasitic diseases affecting humans.

25 Aug 2016

New genetic markers linked to fast rate of nicotine metabolism in smokers may raise risk for lung cancer

University of Hawai'i Cancer Center researchers discovered new genetic markers associated with a fast rate of nicotine metabolism, which potentially leads smokers to smoke more, thereby, increasing their risk for lung cancer.

25 Aug 2016

Gene News and Research

Latest Gene News and Research

Researcher identifies mechanisms that may cause resistance to BRAF inhibitor

Is the virtual gene panel the way forward asks Congenica at Dx Summit

NEJM publishes MINDACT trial results

NanoScope awarded AGI Grant to re-sensitize photo-degenerated retinal areas with MCO

Basic cell biology research into neurodegeneration may fuel understanding of neurodegenerative diseases

Study suggests microRNAs may connect inflammation with heart disease risk in obese people

Researchers explore molecular mechanisms through which lead exposure may affect neural stem cells

SSRI treatment improves cognitive and social functioning in young children with fragile X

Kobe University researchers develop new technique for high-level genome editing operation

Naturally-occurring sugars in woman's breast milk may protect infants against life threatening bacteria

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

Study reveals how pluripotency differs among mice, monkeys, and humans

Gene fusions in esophageal adenocarcinomas offer new molecular insights into lethal cancer

Research findings point to potential drug targets to improve angiogenesis in diabetes patients

Breakthrough in cancer cell screening advances personalised treatment of childhood leukaemia

New findings into the biology of progressive hearing loss

UCSF researchers identify new strategy to cultivate beneficial energy-burning fat

New study looks to saliva of humans and primates to gain insights into evolution

Research findings pave way to effective strategies for treatment of visceral leishmaniasis

New genetic markers linked to fast rate of nicotine metabolism in smokers may raise risk for lung cancer

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