Gene News and Research

Latest Gene News and Research

MTfp-siRNA reduces blood vessel infarct, improves overall brain activity in ischemic stroke model

BIOASIS TECHNOLOGIES INC., a pioneering biopharmaceutical company focused on overcoming the limitations of therapeutic drug delivery across the blood-‐brain barrier (BBB), announces the results from an animal ischemic stroke model performed at the National Research Council Canada with the biOasis Transcend carrier peptide, MTfp and siRNA (MTfp-‐siRNA).

19 Mar 2015

BCM-95 Curcumin improves chemotherapy's effectiveness in killing chemoresistant cancer cells

Cancer cell resistance to chemotherapy is a major cause of death in patients with colorectal cancer. In a first-of-its-kind study, BCM-95 Curcumin was found to improve chemotherapy's effectiveness in killing chemoresistant cells via a mechanism not previously identified.

19 Mar 2015

Scientists identify mystery behind cell-signaling breakdown that causes heart failure

Working with lab animals and human heart cells, scientists from Johns Hopkins and other institutions have identified what they describe as "the long-sought culprit" in the mystery behind a cell-signaling breakdown that triggers heart failure. The condition, which affects nearly 6 million Americans and 23 million people worldwide, is marked by progressive weakening and stiffening of the heart muscle and the organ's gradual loss of blood-pumping ability.

19 Mar 2015

New approach to improve cardiac regeneration

The heart tissue of mammals has limited capacity to regenerate after an injury such as a heart attack, in part due to the inability to reactivate a cardiac muscle cell and proliferation program. Recent studies have indicated a low level of cardiac muscle cell (cardiomyocytes) proliferation in adult mammals, but it is insufficient to repair damaged hearts.

19 Mar 2015

New scoring system may help predict memory and thinking problems in elderly people

Researchers have developed a new scoring system to help determine which elderly people may be at a higher risk of developing the memory and thinking problems that can lead to dementia, according to a new study published in the March 18, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

19 Mar 2015

New microarray-based tool provides fast, reliable assessment of vaginal health

A new microarray-based tool, called VaginArray, offers the potential to provide a fast, reliable and low-cost assessment of vaginal health and diagnoses of infections. The research is published ahead of print March 2, in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology.

19 Mar 2015

New bodily process may explain low blood oxygen levels for cystic fibrosis patients with lung infection

Researchers have defined a new bodily process in mice that may explain why blood oxygen levels are lower for patients with cystic fibrosis when they get a lung infection.

19 Mar 2015

UVA researcher identifies potential therapeutic target for myotonic muscular dystrophy

A doctor who was one of the discoverers of the gene responsible for myotonic muscular dystrophy has now identified a therapeutic that could modify progression of muscle damage and muscle dysfunction associated with the disease - issues that cause patients significant disability and deterioration in quality of life.

19 Mar 2015

Genetic markers may help decide who benefits from aspirin, NSAIDs in lowering risk of colorectal cancer

An Indiana University cancer researcher and her colleagues have identified genetic markers that may help determine who benefits from regular use of aspirin and other nonsteroidal anti-inflammatory drugs for lowering one's risk of developing colorectal cancer.

18 Mar 2015

UT Southwestern neuroscientists identify key brain cells that control circadian rhythms

UT Southwestern Medical Center neuroscientists have identified key cells within the brain that are critical for determining circadian rhythms, the 24-hour processes that control sleep and wake cycles, as well as other important body functions such as hormone production, metabolism, and blood pressure.

18 Mar 2015

Researchers identify promising new approach to treat pulmonary fibrosis

By uncovering the mechanism by which fibrous tissue cells in the lung multiply, researchers at The Saban Research Institute of Children's Hospital Los Angeles, along with colleagues in Mexico and Canada, have identified a promising new approach for the treatment of pulmonary fibrosis.

18 Mar 2015

Gentronix signs three-year technology access deal with SIMM

UK based Gentronix Limited, the specialist genetic toxicology company, today announced it has signed a three year technology access deal with one of China's most prestigious research intensive institutes, Shanghai Institute Materia Medica, Chinese Academy of Sciences.

18 Mar 2015

Virginia Tech researchers use genome-editing method to study lethal disease-carrying animal

Life science researchers at Virginia Tech have accelerated a game-changing technology that's being used to study one of the planet's most lethal disease-carrying animals.

18 Mar 2015

GenomeNext completes whole genome sequencing analysis at unprecedented 1,000 genomes per day

GenomeNext, LLC, a leader in genomic data management and integrated analysis, announced today that, through the "Intel Heads In The Clouds Challenge on Amazon Web Services" with support from JHC Technology, and in conjunction with Nationwide Children's Hospital, has benchmarked whole genome sequencing analysis at an unprecedented 1,000 genomes per day.

18 Mar 2015

DNA sequence determines flexibility, stability of DNA package inside microscopic cell

To pack two meters of DNA into a microscopic cell, the string of genetic information must be wound extremely carefully into chromosomes. Surprisingly the DNA's sequence causes it to be coiled and uncoiled much like a yoyo, scientists reported in Cell.

18 Mar 2015

Scientists identify how mRNA deciphers critical information within genetic code

Case Western Reserve scientists have discovered that speed matters when it comes to how messenger RNA (mRNA) deciphers critical information within the genetic code — the complex chain of instructions critical to sustaining life. The investigators' findings, which appear in the March 12 journal Cell, give scientists critical new information in determining how best to engage cells to treat illness — and, ultimately, keep them from emerging in the first place.

18 Mar 2015

Penn researchers find evidence of new culprit in colon cancer

Colon cancer is a heavily studied disease -- and for good reason. It is one of the leading causes of cancer-related deaths worldwide, and its numbers are on the rise, from 500,00 deaths in 1990 to 700,000 in 2010.

17 Mar 2015

Researchers identify new gene variants that could contribute to sporadic motor neurone disease

Researchers have identified a new host of gene variants that could make people vulnerable to sporadic motor neurone disease, according to a report published today in the journal, Scientific Reports.

17 Mar 2015

Study defines new subtype of 'lethal' prostate cancer

A University of Colorado Cancer Center study published in the journal Cancer Research defines a new, distinct subtype of "lethal" prostate cancer marked by the loss of two genes, MAP3K7 and CHD1. Overall about 10 percent of men with prostate cancer will die from the disease.

16 Mar 2015

Combined use of enalapril and folic acid can significantly reduce risk of first stroke

In a study that included more than 20,000 adults in China with high blood pressure but without a history of stroke or heart attack, the combined use of the hypertension medication enalapril and folic acid, compared with enalapril alone, significantly reduced the risk of first stroke, according to a study appearing in JAMA. The study is being released to coincide with its presentation at the American College of Cardiology Annual Scientific Session.

16 Mar 2015

Gene News and Research

Latest Gene News and Research

MTfp-siRNA reduces blood vessel infarct, improves overall brain activity in ischemic stroke model

BCM-95 Curcumin improves chemotherapy's effectiveness in killing chemoresistant cancer cells

Scientists identify mystery behind cell-signaling breakdown that causes heart failure

New approach to improve cardiac regeneration

New scoring system may help predict memory and thinking problems in elderly people

New microarray-based tool provides fast, reliable assessment of vaginal health

New bodily process may explain low blood oxygen levels for cystic fibrosis patients with lung infection

UVA researcher identifies potential therapeutic target for myotonic muscular dystrophy

Genetic markers may help decide who benefits from aspirin, NSAIDs in lowering risk of colorectal cancer

UT Southwestern neuroscientists identify key brain cells that control circadian rhythms

Researchers identify promising new approach to treat pulmonary fibrosis

Gentronix signs three-year technology access deal with SIMM

Virginia Tech researchers use genome-editing method to study lethal disease-carrying animal

GenomeNext completes whole genome sequencing analysis at unprecedented 1,000 genomes per day

DNA sequence determines flexibility, stability of DNA package inside microscopic cell

Scientists identify how mRNA deciphers critical information within genetic code

Penn researchers find evidence of new culprit in colon cancer

Researchers identify new gene variants that could contribute to sporadic motor neurone disease

Study defines new subtype of 'lethal' prostate cancer

Combined use of enalapril and folic acid can significantly reduce risk of first stroke

eBook: Using iPSCs models for human disease research and drug discovery eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich