Gene News and Research

Latest Gene News and Research

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

A new study shows how mutation of the ADAR1 gene sets off biochemical pathways that produce an autoimmune response that harms the developing brain and other areas of the body.

2 Aug 2022

Researchers characterize a novel gene likely to cause neurological disorders in humans

A multidisciplinary study led by Vanja Nagy (LBI-RUD/CeMM/MedUni Vienna) and Josef Penninger (UBC/IMBA) characterized a novel gene, known as FIBCD1, to be likely causative of a new and rare neurodevelopmental disorder. Using data from two young patients with neurological symptoms, the researchers from both groups found evidence of a novel function for the FIBCD1 gene in the brain, and a potentially pivotal role in diseases such as autism, ADHD, schizophrenia, and neurodegenerative disorders including Alzheimer's. The study makes an important contribution to the understanding of the extracellular matrix in the brain and its associated neurological diseases.

2 Aug 2022

TransCode and MD Anderson scientists collaborate to validate therapeutic and diagnostic candidates

The University of Texas MD Anderson Cancer Center and TransCode Therapeutics, Inc. today announced a strategic alliance to advance TransCode's pipeline of RNA-targeted oncology therapeutic and diagnostic candidates.

2 Aug 2022

What are the hidden sources of SARS-CoV-2 evolution?

A recent article published in Transplant Infectious Disease examined case reports on SARS-CoV-2 evolution in immunosuppressed cohorts.

2 Aug 2022

Asexual reproduction results in more harmful genetic mutations than sexual reproduction

A team led by biologists at The University of Texas at Arlington has published a study supporting the theory that species that reproduce asexually have more harmful genetic mutations than those utilizing sexual reproduction.

1 Aug 2022

Gene mutation responsible for hereditary hemochromatosis may be a risk factor for movement disorders

A disorder called hereditary hemochromatosis, caused by a gene mutation, results in the body absorbing too much iron, leading to tissue damage and conditions like liver disease, heart problems and diabetes.

1 Aug 2022

Würzburg scientists are working on the development of new drugs to combat monkeypox

Poxviruses pose a threat to humanity that should be taken seriously, as the current outbreak of monkeypox shows.

1 Aug 2022

Researchers find mechanisms behind the development of congenital birth defect

About one percent of the world population is born with a congenital heart defect, which affects about 40,000 U.S. births each year, but how these particular birth defects come about is largely unknown.

1 Aug 2022

Epigenetic changes prevent iron-associated programmed cell death in leukemia, research shows

The article, published in the journal Redox Biology by the group of Dr. Manel Esteller, shows that epigenetic changes prevent iron-associated programmed cell death in leukemia and show a new target for treatment with experimental drugs.

1 Aug 2022

What is the role of vitamin D in pandemic H1N1 influenza and SARS-CoV-2 infection?

A recent study published in Nutrients found that vitamin D is vital for lung protection from viral infection.

1 Aug 2022

Innovative microscopy method reveals how neurons struggle to reach their destination in Rett syndrome models

Using an innovative microscopy method, scientists at The Picower Institute for Learning and Memory at MIT observed how newborn neurons struggle to reach their proper places in advanced human brain tissue models of Rett syndrome, producing new insight into how developmental deficits observed in the brains of patients with the devastating disorder may emerge.

29 Jul 2022

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

Wake Forest Institute for Regenerative Medicine researchers are using a tumor organoid system to examine the effects of metabolites secreted by bacteria on a specialized immunotherapy – immune checkpoint blockage, a promising cancer treatment development – to determine why some patients don't respond or develop a resistance to the treatment over time.

29 Jul 2022

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance developed by University of Bristol scientists is published in Nucleic Acids Research.

29 Jul 2022

Understanding the genetic testing-related information needs of ovarian cancer patients

JMIR Publications recently published "Understanding the Information Needs of Patients With Ovarian Cancer Regarding Genetic Testing to Inform Intervention Design: Interview Study" in JMIR Cancer, which reported that experts in gynecological cancer care recommend that all patients with invasive or high-grade ovarian cancer (OC) undergo genetic testing.

29 Jul 2022

Two Weill Cornell doctoral students receive Gilliam Fellowships for Advanced Study from HHMI

Two doctoral students at Weill Cornell Graduate School of Medical Sciences have been awarded prestigious Gilliam Fellowships for Advanced Study from the Howard Hughes Medical Institute.

29 Jul 2022

Ultra-precise gene therapy technologies could edit or silence faulty genes causing fatal heart diseases

An injectable cure for inherited heart muscle conditions that can kill young people in the prime of their lives could be available within a few years, after an international team of researchers were announced as the winners of the British Heart Foundation's Big Beat Challenge.

29 Jul 2022

Gene News and Research

Latest Gene News and Research

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

Researchers characterize a novel gene likely to cause neurological disorders in humans

TransCode and MD Anderson scientists collaborate to validate therapeutic and diagnostic candidates

What are the hidden sources of SARS-CoV-2 evolution?

Asexual reproduction results in more harmful genetic mutations than sexual reproduction

Gene mutation responsible for hereditary hemochromatosis may be a risk factor for movement disorders

Würzburg scientists are working on the development of new drugs to combat monkeypox

Researchers find mechanisms behind the development of congenital birth defect

Epigenetic changes prevent iron-associated programmed cell death in leukemia, research shows

What is the role of vitamin D in pandemic H1N1 influenza and SARS-CoV-2 infection?

Innovative microscopy method reveals how neurons struggle to reach their destination in Rett syndrome models

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Understanding the genetic testing-related information needs of ovarian cancer patients

Two Weill Cornell doctoral students receive Gilliam Fellowships for Advanced Study from HHMI

Ultra-precise gene therapy technologies could edit or silence faulty genes causing fatal heart diseases

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

The global mutation landscape of the SARS-CoV-2 non-structural protein 1

Cross-reactive SARS-CoV-2 antibodies after exposure to avian coronavirus vaccine

New imaging technique reveals subtle details about pathology in a rare eye disease

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting