Gene News and Research

Latest Gene News and Research

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience.

4 Aug 2022

What is the severity of SARS-CoV-2 Omicron BA.4 and BA.5 variant infections in relation to BA.2 infections?

Researchers compared clinical outcomes of COVID-19 cases due to SARS-CoV-2 Omicron BA.2 and Omicron BA.4/BA.5 variants based on the Kaiser Permanente Southern California (KPSC) health records between April 29 and July 2, 2022.

4 Aug 2022

CHOP helps launch new computational platform to harmonize pediatric cancer data

Children's Hospital of Philadelphia has helped launch a new computational platform that will harmonize pediatric cancer data, allowing researchers, pharmaceutical companies, and advocacy groups to accelerate the pace of drug development for pediatric cancer.

4 Aug 2022

Researchers identify a component in the intestine that plays key role in repairing damaged tissue

Investigators at Cedars-Sinai and the University of California, San Francisco have identified a component in the intestine that plays a critical role in repairing damaged tissue.

4 Aug 2022

New study uncovers a likely proteome signature for reductive stress cardiomyopathy

Two years ago, University of Alabama at Birmingham researchers and colleagues reported that reductive stress - an imbalance in the normal oxidation/reduction, or redox, homeostasis - caused pathological changes associated with heart failure in a mouse model.

3 Aug 2022

Study: Genes involved in coronary heart disease may be nearly the same for everyone

The genes involved in coronary heart disease, the most common form of heart disease, appear to be nearly the same for everyone, according to a VA study.

3 Aug 2022

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

Investigators from Cedars-Sinai Cancer have identified genetic signatures that could predict whether tumors in patients with bladder and other cancers will respond to immunotherapy.

3 Aug 2022

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

A new study revealed that the replication of the ancestral strain of SARS-CoV-2 is less efficient in nasal epithelial cells (NECs) of children.

3 Aug 2022

Researchers assess Alzheimer's disease risk and anti-diabetic drugs

In a new study, researchers assessed the genetic variation among targets of Alzheimer's disease risk and anti-diabetic drugs.

3 Aug 2022

Low neutralization of Omicron BA.5 after four doses of mRNA COVID-19 vaccine

Researchers assessed the neutralization of SARS-CoV-2 Omicron variant after messenger ribonucleic acid (mRNA) vaccination.

3 Aug 2022

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

In this interview, we speak to Tom Kostrzewski, VP of Science and Technology at CN Bio, about their organ-on-a-chip product and the future of drug discovery.

From CN Bio Innovations Ltd 3 Aug 2022

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

Liver cancer's rapid growth leads to a vulnerability in its energy-production and cell-building processes that may be potently exploited with a new combination-treatment strategy, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

3 Aug 2022

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

A fruit fly genome is not a just made up of fruit fly DNA – at least for one fruit fly species. New research from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) shows that one fruit fly species contains whole genomes of a kind of bacteria, making this finding the largest bacteria-to-animal transfer of genetic material ever discovered. The new research also sheds light on how this happens.

3 Aug 2022

Drugs with antiviral activity against monkeypox virus

In a recent study posted as an accepted manuscript in the journal Clinical Infectious Diseases, researchers from the University of Oklahoma described three drugs with antiviral activity against the monkeypox virus (MPXV).

2 Aug 2022

Timothy Huang receives $2.8 million to continue research on Alzheimer's disease

Timothy Huang, Ph.D., has been awarded $2.8 million by the National Institute on Aging (NIA) to continue his work on Alzheimer's disease.

2 Aug 2022

Gene therapy approach delays disease onset in humanized mouse models of familial ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the progressive loss of motor neurons in the brain and spinal cord responsible for voluntary movements and muscle control.

2 Aug 2022

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Colorectal tumors are a common adverse effect of chronic inflammation of the intestine. In a new study, researchers from Japan and China demonstrate that mice models with dendritic cell immunoreceptor (DCIR) protein deficiency are resistant to colonic tumors induced by dextran sodium sulfate and azoxymethane.

2 Aug 2022

Gene News and Research

Latest Gene News and Research

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

What is the severity of SARS-CoV-2 Omicron BA.4 and BA.5 variant infections in relation to BA.2 infections?

CHOP helps launch new computational platform to harmonize pediatric cancer data

Researchers identify a component in the intestine that plays key role in repairing damaged tissue

New study uncovers a likely proteome signature for reductive stress cardiomyopathy

Study: Genes involved in coronary heart disease may be nearly the same for everyone

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

Researchers assess Alzheimer's disease risk and anti-diabetic drugs

Low neutralization of Omicron BA.5 after four doses of mRNA COVID-19 vaccine

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

Drugs with antiviral activity against monkeypox virus

Timothy Huang receives $2.8 million to continue research on Alzheimer's disease

Gene therapy approach delays disease onset in humanized mouse models of familial ALS

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Study identifies pivotal role of FIBCD1 gene in neurodevelopmental disorders

Hormonal treatment provides long-term benefit for premenopausal women with breast cancer

Microvascular disease and Alzheimer's associated with more white matter damage, more inflammation

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting