Gene News and Research

Latest Gene News and Research

Next-generation sequencing system yields results comparable to traditional diagnostics

In the pursuit of accurate diagnoses for illnesses, doctors have traditionally used multiple methods — including culturing patient samples on a wide variety of media, reviewing countless medical records and analyzing clinical data using complex mathematical algorithms — to try to identify the bacterium, virus, fungus or other pathogen responsible for an infection.

10 Aug 2022

Mount Sinai receives $500,000 SU2C grant to identify therapeutic combinations for KRAS-mutant lung cancers

Mount Sinai is leading a team of lung cancer researchers that has been awarded a three-year, $500,000 grant from Stand Up To Cancer to explore therapeutic approaches to lung tumors with mutations in the KRAS gene, an undertaking that could have a significant impact for a large population of cancer patients who currently lack effective treatment options.

9 Aug 2022

Pathogens in ancient DNA could explain how two civilizations collapsed

The current study has strongly indicated the presence of Y. pestis and S. enterica on the island of Crete that contributed to societal changes during 2,000 BCE.

9 Aug 2022

The eyes of mutant zebrafish help understand the role of a protein in preventing cell death

Around 15 years ago, a group of researchers discovered mutant zebrafish. The eyes of these zebrafish did not develop correctly, resulting in them being significantly smaller than the eyes of wild zebrafish.

9 Aug 2022

Researchers create the most bio-realistic and complex computer models of brain cells

Cedars-Sinai investigators have created the most bio-realistic and complex computer models of individual brain cells - in unparalleled quantity.

9 Aug 2022

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

The study, which includes the first resource detailing the role of microRNAs in the wound-repair process, shows that aberrant levels of a trio of microRNAs may impair healing in venous ulcers.

9 Aug 2022

Study uncovers how common genetic mutations cause renal cancer

The understanding of the link between common genetic mutations and certain cancers is increasing.

9 Aug 2022

A genome-wide catalog of rare copy-number variant associations for 54 disease phenotypes

A recent study published in Cell illustrated a human genome map with dosage sensitivity across disorders.

9 Aug 2022

Evaluating vaccine effectiveness against Omicron BA.5 and BA.2 in Portugal

Researchers estimated the vaccine effectiveness (VE) of the primary and booster doses of COVID-19 vaccines against reinfection by Omicron BA.5 and BA.2 lineages and severe post-infection outcomes.

9 Aug 2022

Grape consumption alters gene expression in the brain and has positive effects on behavior and cognition

Recent studies released by Dr. John Pezzuto and his team from Western New England University show "astonishing" effects of grape consumption and "remarkable" impacts on health and on lifespans.

9 Aug 2022

Novel AI tools accurately predict the role of DNA’s regulatory elements

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to two recent studies in Nature Genetics.

9 Aug 2022

Overnight EEG studies may help inform care for girls with Rett syndrome

In Rett syndrome, a genetic condition affecting girls almost exclusively, mutations in the MECP2 gene cause a regression of language and motor skills starting at 12 to 18 months of age.

8 Aug 2022

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Cystic fibrosis remains an incurable genetic disorder which impairs lung function and significantly reduces life expectancy.

8 Aug 2022

Disruption of the circadian clocks plays a key role in weight gain

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.

8 Aug 2022

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Young people who received doses of tisagenlecleucel, a chimeric antigen receptor T cell (CAR-T) therapy, at the higher end of the FDA-approved dosing range had significantly better survival rates at one year compared with those who received lower doses within this range, according to research published today in Blood Advances.

8 Aug 2022

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Researchers from Spain have identified an immune expression signature in surgical specimens associated with disease progression for non-complete pathological responders patients treated with neo adjuvant chemo-immunotherapy, which could help the follow-up and therapeutic management of these high-risk patients.

8 Aug 2022

Gene News and Research

Latest Gene News and Research

Next-generation sequencing system yields results comparable to traditional diagnostics

Mount Sinai receives $500,000 SU2C grant to identify therapeutic combinations for KRAS-mutant lung cancers

Pathogens in ancient DNA could explain how two civilizations collapsed

The eyes of mutant zebrafish help understand the role of a protein in preventing cell death

Researchers create the most bio-realistic and complex computer models of brain cells

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

Study uncovers how common genetic mutations cause renal cancer

A genome-wide catalog of rare copy-number variant associations for 54 disease phenotypes

Evaluating vaccine effectiveness against Omicron BA.5 and BA.2 in Portugal

Grape consumption alters gene expression in the brain and has positive effects on behavior and cognition

Novel AI tools accurately predict the role of DNA’s regulatory elements

Overnight EEG studies may help inform care for girls with Rett syndrome

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Disruption of the circadian clocks plays a key role in weight gain

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Research progress on the three-dimensional interaction between virus and host genome

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting