Gene News and Research

Latest Gene News and Research

Gut microbial and immune parameters linked to heterogeneous inter-personal COVID-19 vaccine-triggered immunity

A new study identified the gut microbial and immune variables linked to heterogeneous messenger ribonucleic acid (mRNA) COVID-19 vaccine responses between individuals.

11 Aug 2022

Azelastine nasal spray could decrease SARS-CoV-2 load

A new study illustrated that early azelastine nasal spray therapy might lower the SARS-CoV-2 load among virus-infected patients.

11 Aug 2022

Wastewater surveillance expanded to detect the presence of monkeypox

An ongoing program that monitors wastewater for the presence of SARS-CoV-2 and which has effectively predicted subsequent surges in COVID-19 cases in San Diego has been expanded to detect the presence of monkeypox.

11 Aug 2022

Transposable element controls the immune system to favor host survival during virus infection

Researchers from UNSW Sydney have discovered that a particular transposable element, or jumping gene, in the genome has a profound effect on the immune response to virus infection.

11 Aug 2022

Study aims to understand how female fertility is established at the molecular level

Fertility is finite for mammalian females. From birth, females possess a limited number of primordial follicles, collectively called the ovarian reserve. Within each follicle is an oocyte that eventually becomes an egg. But with age, the follicles in the ovarian reserve decrease.

11 Aug 2022

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential for confirming if cell lines are usable.

11 Aug 2022

Gene expression in male and female brains become more similar with age, study says

When male and female fruit flies age, their brains become desexualized. Age-related changes take place in both sexes, but the male brain becomes feminized to a larger extent than the female brain becomes masculinized. This is the conclusion of a study performed by a research group at Linköping University. The findings are published in the journal Proceedings of the Royal Society of London B.

11 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

Traditional Chinese medicine reduces severity of radiation-induced gastrointestinal mucositis in rats

For tens of thousands of Australians who receive radiotherapy as part of their cancer treatment, mucositis is a serious side effect that may cause inflammation, ulcers, diarrhea, nausea and vomiting, abdominal pain and bloating.

11 Aug 2022

How ultraprocessed foods affect gut microbiome and health

Researchers describe the association between the consumption of ultraprocessed foods and chronic medical conditions.

10 Aug 2022

Scientists discover new target for treatment of premature aging disorders

A stretch of DNA that hops around the human genome plays a role in premature aging disorders, scientists at the Salk Institute and King Abdullah University of Science and Technology in Saudi Arabia have discovered.

10 Aug 2022

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

A monoclonal antibody, mepolizumab, decreased asthma attacks by 27% in Black and Hispanic children and adolescents who have a form of severe asthma, are prone to asthma attacks and live in low-income urban neighborhoods, a National Institutes of Health clinical trial has found.

10 Aug 2022

Epidural lidocaine injections show promise for treating psoriasis

Psoriasis is a chronic inflammatory, debilitating skin disorder. Although there is no cure for psoriasis, several treatment options can inhibit inflammation and relieve signs and symptoms of this disease.

10 Aug 2022

Scientists explore ecological firewalls for the containment of synthetic microbes

In a new study, researchers described ecological firewalls (EFWs) to contain synthetic microbes.

10 Aug 2022

Understanding the emotions behind memories

In this interview, we speak to Professor Kay Tye about her latest research into memories and how we can start to understand the emotions behind them.

10 Aug 2022

A direct lineage-typing RT-PCR assay reveals insights into the transition from Omicron BA.1 to BA.2 dominance in Sweden

Researchers monitored the remarkably rapid Omicron BA.1 to BA.2 sublineage dominance transition in the Swedish population in early 2022 on a day-to-day basis using a customized lineage-typing RT-PCR assay.

10 Aug 2022

Coronavirus biology: viral RNA synthesis, origin, and vaccines

Researchers analyzed the characteristics of coronaviruses and novel CoV vaccine candidates.

10 Aug 2022

IRB scientists identify critical spots on the genome where gene editing could cause an unwanted response

CRISPR/Cas9 is a commonly used, very precise, gene editing technique whose development, by Jennifer A. Doudna and Emmanuelle Charpentier, was recognised with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors", CRISPR allows the introduction of the desired DNA sequence into (virtually) any spot of the genome, thus modifying or inactivating a gene. This technique is widely used in biomedical research and some CRISPR-based therapies are in clinical trials for the treatment of human blood disorders, some types of cancer and HIV, among other conditions.

10 Aug 2022

Researchers identify novel molecular pathway that suppresses the spread of glioblastoma

UT Southwestern researchers have identified a molecular pathway responsible for the spread of glioblastoma to surrounding tissue in the brain, as well as an existing drug that curbed tumor growth in animal models.

10 Aug 2022

Study evaluates the tumor-modulatory effects of opsins on melanoma cancer

Melanopsin (OPN4) is a light-sensing protein found in skin and retina cells. A new study conducted at the University of São Paulo (USP) in Brazil suggests that OPN4 can also participate in the development and progression of melanoma, the most aggressive type of skin cancer.

10 Aug 2022

Gene News and Research

Latest Gene News and Research

Gut microbial and immune parameters linked to heterogeneous inter-personal COVID-19 vaccine-triggered immunity

Azelastine nasal spray could decrease SARS-CoV-2 load

Wastewater surveillance expanded to detect the presence of monkeypox

Transposable element controls the immune system to favor host survival during virus infection

Study aims to understand how female fertility is established at the molecular level

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

Gene expression in male and female brains become more similar with age, study says

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

Traditional Chinese medicine reduces severity of radiation-induced gastrointestinal mucositis in rats

How ultraprocessed foods affect gut microbiome and health

Scientists discover new target for treatment of premature aging disorders

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

Epidural lidocaine injections show promise for treating psoriasis

Scientists explore ecological firewalls for the containment of synthetic microbes

Understanding the emotions behind memories

A direct lineage-typing RT-PCR assay reveals insights into the transition from Omicron BA.1 to BA.2 dominance in Sweden

Coronavirus biology: viral RNA synthesis, origin, and vaccines

IRB scientists identify critical spots on the genome where gene editing could cause an unwanted response

Researchers identify novel molecular pathway that suppresses the spread of glioblastoma

Study evaluates the tumor-modulatory effects of opsins on melanoma cancer

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting