Genetics News and Research

Latest Genetics News and Research

New tool that may prove to be invaluable for investigating the long-term mutagenic effects of chemotherapy and radiation

Scientists have developed a new tool that may prove to be invaluable for investigating the long-term mutagenic effects of chemotherapy and radiation, therapies that are widely used for the treatment of cancer.

17 Oct 2005

New genetic discovery may help explain why some people develop high blood pressure and others don't

It also gives new insight into how the kidneys govern the balance of salt in the body, a crucial task for regulating blood pressure. And, it reveals how a gene already linked to behavior and mental health can play a role in the body, as well as the brain.

17 Oct 2005

Significant step forward in the genome era

In what promises to be a significant step forward in the genome era, the National Human Genome Research Institute (NHGRI) today announced plans to devote a portion of its large-scale sequencing capacity to efforts aimed at identifying the genetic roots of specific diseases that have long eluded gene hunters.

17 Oct 2005

Researchers shed light on a key molecular switch in T helper cells

Defects in immune system cells called T helper cells may lead to diseases characterized by a faulty inflammatory response such as autoimmunity and asthma. Understanding the molecular steps involved in how T helper cells mature may help researchers develop treatments for these diseases.

17 Oct 2005

WWOX gene finding could lead to a new strategy for treating lung cancer

The research focused on a gene known as WWOX, which is lost or silenced in a large majority of lung cancers, and in cancers of the breast, ovary, prostate, bladder, esophagus and pancreas. The work was led by scientists at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

17 Oct 2005

New treatment for the pediatric eye cancer retinoblastoma

Investigators at St. Jude Children's Research Hospital have demonstrated in laboratory studies a new treatment for the pediatric eye cancer retinoblastoma that appears to be more effective than the current standard therapy, and more likely to prevent the recurrence of this cancer. A report on their work appears in the October 15 issue of Clinical Cancer Research.

17 Oct 2005

Rett syndrome discovery

The gene responsible for Rett syndrome, a devastating neurological disease found mostly in girls, not only silences some genes but in combination with another also regulates alternative splicing, crucial to the formation of proteins -- a finding that may explain the symptoms associated with this puzzling disorder and others related to it

17 Oct 2005

New findings on brain tumors called ependymomas

Brain tumors called ependymomas that occur in different parts of the central nervous system appear to arise from subpopulations of stem cells called radial glia cells (RGCs), according to investigators at St. Jude Children's Research Hospital. The discovery explains why some identical-looking ependymomas are actually distinctly different diseases, the researchers said.

17 Oct 2005

Tourette syndrome linked to SLITRK1 gene

Tourette syndrome is a distressing condition which affects one in every 100 people.

17 Oct 2005

Research reveals concerns over use of health information

New Economic & Social Research Council (ESRC) funded research has discovered that eight per cent of people are asked to pay a higher premium because of health 'ratings' - twice as many as previously thought.

16 Oct 2005

Ethnic differences in cardiovascular risk factors

Heredity plays a major role in determining the blood lipid profile and heart rate variability of blacks and whites, two major risk factors for coronary artery disease, researchers say.

16 Oct 2005

Gene therapy may prevent the damaging effects of radiation

Gene therapy could be used as an agent to protect normal tissues, including the esophagus and lung, from damage during a second administration of radiation therapy for non-small cell lung cancer, according to an animal study presented by University of Pittsburgh researchers at the 47th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Denver.

16 Oct 2005

Isotretinoin-related birth defects

Isotretinoin (also known as Accutane) is a drug used to treat severe acne, but it can cause birth defects when taken by pregnant women. Because of these risks, the U.S. Food and Drug Administration and Roche Pharmaceuticals (Accutane's manufacturer) developed a voluntary pregnancy prevention program (PPP) in 1988 to try and prevent conception in women taking the drug.

16 Oct 2005

Family history of alcohol dependency does not relate to age of first drink

Having a first alcoholic drink at the early age of 12, 13 or 14 might be influenced more by a child's tendency to do things like lie, steal or skip school than by a family history of alcohol dependency, according to findings by University of Iowa and other investigators.

16 Oct 2005

Researchers find new type of antibiotic against the cholera bacteria

Just as hurricanes in the Gulf states and Guatemala have raised the risks of cholera outbreaks, researchers at Harvard Medical School have identified a new type of antibiotic against the cholera bacteria.

16 Oct 2005

E-cadherin, that cellular touch so important in cancer

E-cadherin is a molecule involved in adhesion between epithelial cells that also seems to have a protective role in cancer, since its loss is associated with tumour progression and metastases formation in a series of different cancers.

16 Oct 2005

Alternative methods to create stem cells successful in mice-studies

According to researchers in the U.S. two alternative methods for making embryonic stem cells, work in mice and could lead to a less controversial way to grow them.

16 Oct 2005

Discovery of agent that can suppress cancer development

In a case of basic science detective work, researchers at The University of Texas M. D. Anderson Cancer Center have solved the puzzle of the "inconsistent biomarker" and, in the process, may have discovered an agent that can suppress cancer development.

13 Oct 2005

First gene mutation associated with Tourette syndrome

Researchers have identified the first gene mutation associated with Tourette syndrome - opening a new avenue for understanding the complex disorder that causes muscle and vocal tics.

13 Oct 2005

Relationship between drinking early in adolescence and later negative outcomes

Alcohol experimentation in late childhood or early adolescence is a common event. An early age of first drink (AFD), however, is associated with a variety of negative outcomes.

13 Oct 2005