Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Scientists use latest sequencing technology to review genetic makeup of ataxias syndrome

According to a recent study published in JAMA Neurology, Northwestern Medicine scientists have examined more than a century of data of the genetic makeup of ataxias, a neurodegenerative disorder, to better understand the different forms of this devastating disease and how it affects patients.

8 Nov 2016

Stanford researchers discover new biological markers to measure progression of Huntington's disease

Researchers at Stanford University School of Medicine have identified several new biological markers to measure the progression of the inherited neurodegenerative disorder Huntington's disease (HD).

7 Nov 2016

Computer-adaptive tests to measure health-related quality of life in Huntington's disease patients

Huntington's disease is an inherited disease that leads to problems with movement, thinking and mood which can negatively affect an individual's quality of life.

21 Oct 2016

URMC scientists receive award to explore new treatments for Huntington's disease

A new award from the CHDI Foundation will advance promising research that aims to slow the progression of Huntington's disease.

13 Oct 2016

Johns Hopkins researchers identify protein that triggers brain cell death from strokes and injuries

Despite their different triggers, the same molecular chain of events appears to be responsible for brain cell death from strokes, injuries and even such neurodegenerative diseases as Alzheimer's.

7 Oct 2016

New study identifies potential therapeutic option for treatment of Huntington's disease

A new scientific study reveals one way to stop proteins from triggering an energy failure inside nerve cells during Huntington's disease. Huntington's disease is an inherited genetic disorder caused by mutations in the gene that encodes huntingtin protein.

14 Sep 2016

Novel DNA-altering method could lead to more treatment options for diseases

Researchers in Singapore have developed a new protein that can alter DNA in living cells with much higher precision than current methods.

13 Sep 2016

New treatment reduces activity of Huntington's disease gene for several months in mice

A single injection of a new treatment has reduced the activity of the gene responsible for Huntington's disease for several months in a trial in mice.

9 Sep 2016

Experimental co-culture approach facilitates study of cellular events underlying Huntington's disease

Using an experimental co-culture approach in which two different types of neurons from a mouse model of Huntington's disease (HD) are grown side-by-side, connecting to form critically impacted circuits, researchers at University of California San Diego School of Medicine have identified a subunit of a protein that, when expressed, reverse the mutated gene effects responsible for HD.

6 Sep 2016

Modifying huntingtin protein protects against behavioral symptoms in Huntington's model mice

There is new hope in the fight against Huntington's disease. Scientists at the Gladstone Institutes discovered that changing a specific part of the huntingtin protein prevented the loss of critical brain cells and protected against behavioral symptoms in a mouse model of the disease.

16 Aug 2016

MGH investigators discover key molecules essential for sensing proteasome dysfunction

Maintaining appropriate levels of proteins within cells largely relies on a cellular component called the proteasome, which degrades unneeded or defective proteins to recycle the components for the eventual assembly of new proteins.

16 Aug 2016

Novel PET radiotracer reveals epigenetic activity in the human brain for the first time

A novel PET radiotracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital is able for the first time to reveal epigenetic activity - the process that determines whether or not genes are expressed - within the human brain.

11 Aug 2016

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

Many gene mutations that cause neurological disorders have been identified. For example, in a rare neurological disorder such as Huntington’s disease, an autosomal dominant mutation through expansion of CAG (cytosine-adenine-guanine) triplet repeats in the gene coding for the Huntingtin protein results in abnormal protein production.

1 Aug 2016

Researchers discover pathway linking oxidative stress and cysteine in Huntington's disease

Researchers at Johns Hopkins Medicine report they have identified a biochemical pathway linking oxidative stress and the amino acid cysteine in Huntington's disease.

27 Jul 2016

Huntington's disease monkey model embodies full array of symptoms similar to human patients

Transgenic Huntington's disease monkeys display a full spectrum of symptoms resembling the human disease, ranging from motor problems and neurodegeneration to emotional dysregulation and immune system changes, scientists at Yerkes National Primate Research Center, Emory University report.

21 Jul 2016

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Scientists use latest sequencing technology to review genetic makeup of ataxias syndrome

Stanford researchers discover new biological markers to measure progression of Huntington's disease

Computer-adaptive tests to measure health-related quality of life in Huntington's disease patients

URMC scientists receive award to explore new treatments for Huntington's disease

Johns Hopkins researchers identify protein that triggers brain cell death from strokes and injuries

New study identifies potential therapeutic option for treatment of Huntington's disease

Novel DNA-altering method could lead to more treatment options for diseases

New treatment reduces activity of Huntington's disease gene for several months in mice

Experimental co-culture approach facilitates study of cellular events underlying Huntington's disease

Modifying huntingtin protein protects against behavioral symptoms in Huntington's model mice

MGH investigators discover key molecules essential for sensing proteasome dysfunction

Novel PET radiotracer reveals epigenetic activity in the human brain for the first time

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

Researchers discover pathway linking oxidative stress and cysteine in Huntington's disease

Huntington's disease monkey model embodies full array of symptoms similar to human patients

Researchers develop new screening system to measure protein aggregates

Deutetrabenazine may help improve chorea symptoms in patients with HD

Deuteration offers alternative chorea treatment for Huntington disease patients

Neurofibromatosis causes benign tumor formation in normal nervous tissue

Study shows many people may have potential to develop Huntington's disease

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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