Posted in | eBooks

How to use Atomic Force Microscopy in Life Sciences

Atomic force microscopy (AFM) is a high-resolution surface analysis technique that allows for 3D topographic imaging at the nanoscale and multiparametric characterization of the mechanical properties of soft matter, materials, as well as biological samples.

Download the ebook

When it comes to analyzing living cells, challenging biological samples and thick, multilayer tissue samples require purposefully designed instrumentation. BioAFMs are ideal when it comes to these samples, as they allow for measurements under near-physiological or controlled environmental conditions.

AFM, life sciences

BioAFMs can also be seamlessly integrated with advanced optical microscopy to deliver complementary datasets and correlated measurements, offering novel insights into molecular mechanisms and paving the way for new and exciting research applications.

This eBook is a valuable tool for both seasoned AFM users and those still unfamiliar with the technique but interested in learning more about how it can expand their current research capabilities. Readers can expect to find an overview of BioAFM technology, practical tips on getting the most out of the technique, and other key information.

Key Topics Covered:

  • The working principle of BioAFM, including the latest advanced features and imaging modes
  • How to choose cantilevers for specific biological applications
  • Enhancing analysis capabilities through correlative microscopy and the integration of AFM with advanced optical techniques.

A dive into some case studies demonstrating the application of BioAFM in life science research, including the investigation of DNA origami, cellular and molecular dynamics, and microrheological in living cells, as well as AFM-based single-molecule force spectroscopy

Download the ebook

About Bruker Nano Analytics

Bruker BioAFM, former JPK Instruments AG,  is a lead­ing man­u­fac­tur­er of nano-an­a­lyt­i­cal in­stru­ments - par­tic­u­lar­ly based on atom­ic force mi­cro­scope (AFM) and op­ti­cal tweez­ers sys­tems - for life sci­ences and soft mat­ter ap­pli­ca­tions.

We combine the highest technical skills with visionary applications. Our work applies nanotechnology in ways to provide solutions to challenges facing researchers in life sciences and soft matter today. Driven by inspiration and ambition, it is our conviction that only the best tools are good enough for the research of life. We are listening with the ear of a scientist in detail to the current challenges of our customers and find individual solutions for individual problems. This is how we understand our business.

Sponsored Content Policy: publishes articles and related content that may be derived from sources where we have existing commercial relationships, provided such content adds value to the core editorial ethos of News-Medical.Net which is to educate and inform site visitors interested in medical research, science, medical devices and treatments.

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.