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Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so.

22 Sep 2021

Researchers seek to identify the role of hypoxia on red blood cell aging

Red blood cells are the most abundant cell type in blood, carrying oxygen throughout the human body. In blood circulation, they repetitively encounter various levels of oxygen tension.

22 Sep 2021

Discovery of genes opens the door to new treatments for obesity

Promising news in the effort to develop drugs to treat obesity: University of Virginia scientists have identified 14 genes that can cause and three that can prevent weight gain.

22 Sep 2021

Scientists use statistical mechanics to make sense of DNA folding

At more than 2 meters long, the human DNA molecule uses intricate folding patterns to fit into cells while locally unfolding to express genes. Such phenomena, however, are difficult to measure in experiments, and theoretical frameworks explaining them continue to be at odds with one another.

22 Sep 2021

Rice bioengineer receives $1.9 million NIH grant to improve time-release drugs

Time-released drugs are about to get a geometry lesson, thanks to bioengineers at Rice University.

21 Sep 2021

Including Japanese knotweed extract in processed red meat could reduce cancer risk

Bacon could be back on the menu of health-conscious diners thanks to an unlikely salvation: Japanese knotweed.

21 Sep 2021

Study paves the way for development of novel delivery systems to suppress HIV

In a new study supported by the National Institutes of Health, researchers used exosomes, tiny nanoparticles capable of being taken up by cells, to deliver novel protein into the cells of mice infected with HIV. The protein attached to HIVs' genetic material and prevented it from replicating, resulting in reduced levels of HIV in the bone marrow, spleen, and brain.

21 Sep 2021

Researchers provide structural insights into HCV receptor binding and entry

In a new paper published in Nature, scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, describe the structure of a key protein on the surface of the hepatitis C virus (HCV) and how it interacts with its receptor found on some human cells.

21 Sep 2021

Study shows how SARS-CoV-2 viral proteases can be targeted to stop virus replication

Researchers at the University of Liverpool have shown how SARS-CoV-2 viral proteases attack the host cell, and how this can be targeted to stop virus replication in cell culture using existing drugs.

21 Sep 2021

Careful pipetting reduces the stress on cells in culture

Cell viability, defined as the proportion of live cells in a sample, is a fundamental consideration in all cell culture techniques.

From INTEGRA Biosciences 21 Sep 2021

Researchers uncover a molecular mechanism to inhibit aggravation of colitis

The intestinal microbial ecosystem includes diverse species of bacteria. These bacteria can produce bioactive metabolites that directly affect the host's immune system.

21 Sep 2021

Differences in DNA methylation could accurately predict progression of liver disease

Findings of a national study led by the Translational Genomics Research Institute, an affiliate of City of Hope, identify potential biomarkers that might eventually be used to diagnose progressive stages of liver disease.

20 Sep 2021

New open-source, multi-disciplinary simulation platform to study biological processes

Agent-based simulations (ABS) are powerful computational tools that help scientists understand complex biological systems.

20 Sep 2021

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

In a recent study, researchers study the molecular aspects of SARS-CoV-2 host cell entry and inhibition of host-specific cellular mechanisms.

20 Sep 2021

Researchers develop new method to track the development of cancer cells

Changes in individual cancer cells over time may explain why brain tumours develop so differently, and why some cancer cells are resistant to certain treatments.

20 Sep 2021

Two proteins work in tandem to build lifelines to cancer cells, study finds

In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.

20 Sep 2021

Large scale 'proteogenomics' study could offer hope to patients with deadly pancreatic cancer

A large international collaboration led by researchers from the Johns Hopkins Kimmel Cancer Center has identified promising new targets for pancreatic cancer treatment and early diagnosis after examining various aspects of these tumors' genes and proteins.

20 Sep 2021

Life Science News

Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Researchers seek to identify the role of hypoxia on red blood cell aging

Discovery of genes opens the door to new treatments for obesity

Scientists use statistical mechanics to make sense of DNA folding

Rice bioengineer receives $1.9 million NIH grant to improve time-release drugs

Including Japanese knotweed extract in processed red meat could reduce cancer risk

Study paves the way for development of novel delivery systems to suppress HIV

Researchers provide structural insights into HCV receptor binding and entry

Study shows how SARS-CoV-2 viral proteases can be targeted to stop virus replication

Careful pipetting reduces the stress on cells in culture

Researchers uncover a molecular mechanism to inhibit aggravation of colitis

Differences in DNA methylation could accurately predict progression of liver disease

New open-source, multi-disciplinary simulation platform to study biological processes

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

Researchers develop new method to track the development of cancer cells

Two proteins work in tandem to build lifelines to cancer cells, study finds

Large scale 'proteogenomics' study could offer hope to patients with deadly pancreatic cancer

New discovery reveals how immune 'sentinel' cells are maintained

Study highlights the usefulness of organoids for basic research into coronaviruses

Researchers discover new mechanism used by a simple yeast cell to acquire its shape

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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