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Peto's paradox offers new insights into cancer risk across mammals

The cells in the body can be thought of as tiny archery targets, each vulnerable to the deadly arrow of cancer.

23 Dec 2021

Flexibility may maximize the potency of peptides used to treat Type 2 diabetes

A little wiggle room might be just what the doctor ordered. New research suggests that the peptides - short chunks of protein - used to treat Type 2 diabetes may be more effective if they're able to flexibly move back and forth between different shapes.

23 Dec 2021

Recently evolved region of the ‘dark genome’ provides clues to treatment of schizophrenia, bipolar disorder

Scientists investigating the DNA outside our genes - the 'dark genome' - have discovered recently evolved regions that code for proteins associated with schizophrenia and bipolar disorder.

23 Dec 2021

X-ray imaging of cardiac tissue reveals the impact of Covid-19 on the heart

An interdisciplinary research team from the University of Göttingen and Hannover Medical School (MHH) has detected significant changes in the heart muscle tissue of people who died from Covid-19.

23 Dec 2021

Cryo-EM of Omicron variant reveals antibody evasion by spike-ACE2 complex

Researchers compare the obtained binding affinities to wild-type and Delta spike proteins to determine the impact of Omicron mutations.

23 Dec 2021

Researchers identify a key influenza epitope that can targeted for developing universal vaccines

A team led by scientists at Weill Cornell Medicine, Scripps Research and the University of Chicago has identified an important site of vulnerability on influenza viruses—a site that future influenza vaccines and antibody therapies should be able to target to prevent or treat infections by a broad set of influenza strains.

23 Dec 2021

New insights into how red meat-rich diet increases cardiovascular disease risk

A Cleveland Clinic-led study has revealed new insights into how a diet rich in red meat increases risk for cardiovascular disease. The findings were published in Nature Microbiology and build on more than a decade of research by lead author Stanley Hazen, MD, PhD.

23 Dec 2021

Researchers reveal an unrecognized pathway promoting long-term survival of T cells

They are at the forefront in the fight against viruses, bacteria, and malignant cells: the T cells of our immune system. But the older we get, the fewer of them our body produces.

23 Dec 2021

New study shines light on how brain cells die in prion diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP.

22 Dec 2021

Eating sugar is healthy for some Greenlanders with a genetic variation

A genetic variation among some Greenlanders makes sugar healthy – significantly more than for most people.

22 Dec 2021

Researchers receive NIH grants to develop new treatments for neglected tropical diseases

Researchers at Washington University School of Medicine in St. Louis have received two grants from the National Institutes of Health totaling more than $5.5 million to develop new treatments for two types of devastating parasitic infections common in sub-Saharan Africa and Central and South America: river blindness and intestinal worm infections.

22 Dec 2021

Study suggests nitazoxanide fails to reduce the severity of SARS-CoV-2

A new study shows that the optimization of nitazoxanide formulations may allow the review of the potential use of the drug for the treatment of SARS-CoV-2 infection.

22 Dec 2021

Researchers identify new mechanism that impairs cancer cell proliferation and induces death

UAB and Vall d'Hebron researchers identified the mechanism by which inhibitors of the ERK5 protein kinase impair the proliferation of cancer cells and induce their death. The results, obtained using human cancer cell lines, demonstrate that ERK5 inhibition activates cytotoxic autophagy, a process that triggers cancer cell death, without affecting healthy cells. A combination of ERK5 inhibitors and chemotherapy could improve cancer treatment.

22 Dec 2021

Researchers identify new mechanism for DNA invasion of adenoviral COVID-19 vaccines

Adenoviruses have a linchpin protein that stabilizes their DNA until it reaches the infected cell's nucleus. The protein then detaches from the viral genome, and the virus uncoats. Only then are the genes released into the nucleus, which is necessary for the production of new viruses.

22 Dec 2021

Life Science News

Peto's paradox offers new insights into cancer risk across mammals

Flexibility may maximize the potency of peptides used to treat Type 2 diabetes

Recently evolved region of the ‘dark genome’ provides clues to treatment of schizophrenia, bipolar disorder

X-ray imaging of cardiac tissue reveals the impact of Covid-19 on the heart

Cryo-EM of Omicron variant reveals antibody evasion by spike-ACE2 complex

Researchers identify a key influenza epitope that can targeted for developing universal vaccines

New insights into how red meat-rich diet increases cardiovascular disease risk

Researchers reveal an unrecognized pathway promoting long-term survival of T cells

New study shines light on how brain cells die in prion diseases

Eating sugar is healthy for some Greenlanders with a genetic variation

Researchers receive NIH grants to develop new treatments for neglected tropical diseases

Study suggests nitazoxanide fails to reduce the severity of SARS-CoV-2

Researchers identify new mechanism that impairs cancer cell proliferation and induces death

Researchers identify new mechanism for DNA invasion of adenoviral COVID-19 vaccines

Researchers use network modeling to hone in on cancer gene interactions critical to malignancy

Polyrotaxane-based biomaterials enhance the connection between epithelial cells

Researchers discover new function of protein tBID

Star-shaped cells in the brain regulate cognitive flexibility

Deletion of autism-linked gene diminishes myelin in mice

How the SARS-CoV-2 Omicron variant spike protein is changing

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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