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Biologists discover how a protein in our body works

It's an old needlework trick, and a protein in our body knows it: Instead of threading yarn into the eye from the end, it can be easier to pass a loop through it.

29 Nov 2021

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Researchers study human single nucleotide variants (SNVs) using machine learning to identify amino acid changes that alter kinase-bound sequence motifs.

29 Nov 2021

Simple change can maximize a single cell's production of extracellular vesicles

A simple change in the way donor cells are processed can maximize a single cell's production of extracellular vesicles, which are small nanoparticles naturally secreted by cells, according to new research from researchers at the University of Illinois Chicago.

29 Nov 2021

Tomosyn protein's key contribution to heterogeneity of neurons revealed

The versatility of the nervous system comes from not only the diversity of ways in which neurons communicate in circuits, but also their "plasticity," or ability to change those connections when new information has to be remembered, when their circuit partners change, or other conditions emerge.

29 Nov 2021

Study uncovers mechanism for insensitivity to key antimalarial drug in new pathogen variant

Malaria is one of the most dangerous infectious diseases. The causative pathogens are microorganisms of the genus Plasmodium.

29 Nov 2021

Researchers shed light on an important stage of early human embryogenesis for the first time

Scientists have shed light on an important stage of early embryonic development that has never been fully mapped out in humans before.

29 Nov 2021

Study reveals a previously unknown mechanism for pancreatic cancer metastasis

Pancreatic cancer is very aggressive and, unfortunately, has a poor prognosis with a 5-year survival of only 5%. Most deaths related to pancreatic cancer are due to metastasis, which occurs when the tumour invades other organs.

29 Nov 2021

Complex RNA structures could have untapped therapeutic potential in the fight against COVID-19

To the untrained eye, the loops, kinks and folds in the single strand of RNA that makes up the coronavirus genome look like a jumble of spaghetti or tangled yarn. But to researchers like Amanda Hargrove, a chemistry professor at Duke University, the complex shapes that RNA takes on as it folds upon itself could have untapped therapeutic potential in the fight against COVID-19.

26 Nov 2021

Genetic ancestry can explain population-level differences in immune response to the flu virus

A new study aimed at explaining differential susceptibility to viral epidemics reveals that ancestry and associated genetic variation can explain population-level differences in the immune response to the flu virus and perhaps also to COVID-19.

26 Nov 2021

Comprehensive genomic study maps the global resurgence of syphilis

The most comprehensive genomic study of syphilis to date has mapped the recent resurgence of the disease around the world.

26 Nov 2021

Immune response to influenza virus influenced by genetic ancestry

New research at the University of Chicago has found differences in immune pathway activation to influenza infection between individuals of European and African genetic ancestry.

25 Nov 2021

Research reveals how disordered protein interaction orchestrates gene expression

A team led by researchers at Baylor College of Medicine and the Czech Academy of Sciences has uncovered a new piece of the puzzle of how gene expression is orchestrated.

25 Nov 2021

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

LMU immunologists have discovered how mutations in Roquin-1 trigger autoimmunity, but can also improve the body's fight against cancer cells.

25 Nov 2021

Method can help identify proteins in the body affected by chemicals

How do pollutants and other chemicals that we are exposed to affect our health? Researchers from Linköping University, Sweden, have applied a method to identify the proteins in the body affected by chemicals.

25 Nov 2021

Mapping cell structure by fusing protein images and interactions

If cells were "countries", the proteins would be their citizens organized into inter-connected towns and villages.

25 Nov 2021

Mtb's exotoxin secretion and trafficking mechanism revealed

Six years ago, Michael Niederweis, Ph.D., described the first known toxin of the deadly pathogen Mycobacterium tuberculosis (Mtb), an exotoxin that had gone undetected for 132 years.

25 Nov 2021

MIT scientists discover how molecular clusters interact with chromosomes in the nucleus

A cell stores all of its genetic material in its nucleus, in the form of chromosomes, but that's not all that's tucked away in there. The nucleus is also home to small bodies called nucleoli - clusters of proteins and RNA that help build ribosomes.

25 Nov 2021

Scientists use the synchrotron to better understand structure of cancer cells

A team of scientists led by the University of Surrey have used a special particle accelerator facility known as a synchrotron to better understand the structure of cancer cells.

25 Nov 2021

Combination of iota-carrageenan and xylitol as a potential nasal spray for COVID

Researchers determine the inhibition capacity of iota-carrageenan and xylitol in three different candidate preservative-free formulations.

24 Nov 2021

Impeding SARS‑CoV‑2 evolution by targeting low-probability stochastic events

Researchers explore the emergence of more fit SARS-CoV-2 variants using a stochastic evolutionary modeling framework during long-term infections.

24 Nov 2021

Life Science News

Biologists discover how a protein in our body works

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Simple change can maximize a single cell's production of extracellular vesicles

Tomosyn protein's key contribution to heterogeneity of neurons revealed

Study uncovers mechanism for insensitivity to key antimalarial drug in new pathogen variant

Researchers shed light on an important stage of early human embryogenesis for the first time

Study reveals a previously unknown mechanism for pancreatic cancer metastasis

Complex RNA structures could have untapped therapeutic potential in the fight against COVID-19

Genetic ancestry can explain population-level differences in immune response to the flu virus

Comprehensive genomic study maps the global resurgence of syphilis

Immune response to influenza virus influenced by genetic ancestry

Research reveals how disordered protein interaction orchestrates gene expression

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

Method can help identify proteins in the body affected by chemicals

Mapping cell structure by fusing protein images and interactions

Mtb's exotoxin secretion and trafficking mechanism revealed

MIT scientists discover how molecular clusters interact with chromosomes in the nucleus

Scientists use the synchrotron to better understand structure of cancer cells

Combination of iota-carrageenan and xylitol as a potential nasal spray for COVID

Impeding SARS‑CoV‑2 evolution by targeting low-probability stochastic events

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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