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On January 2, 2020, the Berlin-based laboratory instrument manufacturer KNAUER Wissenschaftliche Geräte GmbH was awarded the "CrefoZert" credit rating certificate for the first time by the business information service CreditReform.

From KNAUER Wissenschaftliche Geräte GmbH 9 Jan 2020

Missing a key protein in the brain can cause autism-like behaviors

Scientists at Rutgers University-Newark have discovered that when a key protein needed to generate new brain cells during prenatal and early childhood development is missing, part of the brain goes haywire - causing an imbalance in its circuitry that can lead to long-term cognitive and movement behaviors characteristic of autism spectrum disorder.

9 Jan 2020

First-ever genomic analysis of puberty yields insights into critical areas of human health

In the first-ever genome-scale analysis of the puberty process in humans, researchers at Huntsman Cancer Institute at the University of Utah outline distinct and critical changes to stem cells in males during adolescence.

9 Jan 2020

Common genetic defect in prostate cancer associated with worse prognosis

Like security screening to make sure nothing harmful makes its way into a crowded area, cells in the human body use checkpoints to control their growth and prevent harmful mutations from making their way into new cell populations and causing trouble.

9 Jan 2020

Scientists find way to combine two main coding languages into single 'bilingual' molecule

The nucleic acids of DNA encode genetic information, while the amino acids of proteins contain the code to turn that information into structures and functions. Together, they provide the two fundamental codes underlying all of life.

9 Jan 2020

Insect leaf-wounding produces healthier organic fruit

Texas A&M AgriLife Research scientists found benefits of insect leaf-wounding in fruit and vegetable production. Stress responses created in the fruits and vegetables initiated an increase in antioxidant compounds prior to harvest, making them healthier for human consumption.

9 Jan 2020

Scientists discover how bacterial evolution of antibiotic arsenals is providing new drug blueprints

Scientists from Trinity College Dublin have discovered that two very different species of bacteria have evolved distinct, powerful antibiotic arsenals for use in the war against their bacterial neighbors.

9 Jan 2020

Research reveals cardiac thin filament structure and function

Researchers at Osaka University used electron cryomicroscopy to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution.

9 Jan 2020

Researchers identify synergistic cellular pathways that considerably amplify lifespan

Scientists at the MDI Biological Laboratory, in collaboration with scientists from the Buck Institute for Research on Aging in Novato, Calif., and Nanjing University in China, have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research.

9 Jan 2020

ERS Genomics and New England Biolabs sign agreement to commercialize CRISPR/Cas9 tools, reagents

ERS Genomics Limited, which was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property co-owned by Dr. Emmanuelle Charpentier, today announced it has signed an agreement with New England Biolabs, a global leader in the discovery and production of enzymes for molecular biology applications, granting NEB rights to sell CRISPR/Cas9 tools and reagents.

From New England Biolabs 9 Jan 2020

Avacta and Daewoong Pharmaceutical announce joint venture to develop novel cell and gene therapies

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, and Daewoong Pharmaceutical Co. Ltd., a leading Korean pharmaceutical company, are pleased to announce that they have agreed to establish a joint venture in South Korea, and to enter a collaboration and license agreement for the joint venture to develop the next generation of cell and gene therapies incorporating Affimer proteins to enhance the immune-modulatory effects.

From Avacta Life Sciences Ltd. 9 Jan 2020

New screening platform helped scientists to discover drug-like compounds

A sophisticated new screening platform developed by scientists at Scripps Research has enabled them to discover a set of drug-like compounds, including an ingredient found in sore throat lozenges, that may powerfully protect brain cells from dangerous stresses found in Alzheimer's and other neurodegenerative diseases.

9 Jan 2020

Researchers report first structural model for key enzyme associated with inherited eye diseases

Researchers at the University of New Hampshire have reported the first structural model for a key enzyme, and its activating protein, that can play a role in some genetically inherited eye diseases like retinitis pigmentosa and night blindness.

8 Jan 2020

Researchers use single cell genome sequencing to study malaria transmission

New technology employing single cell genome sequencing of the parasite that causes malaria has yielded some surprising results and helps pave the way for possible new intervention strategies for this deadly infectious disease, according to Texas Biomedical Research Institute Assistant Professor Ian Cheeseman, Ph.D. Dr. Cheeseman was Principal Investigator of a three-year study published in the January 2020 edition of Cell Host & Microbe, a high-impact peer-reviewed publication.

8 Jan 2020

Scientists discover how dying cells prevent dangerous immune reactions

Dying cells in the body can keep the immune system in check, thus preventing unwanted immune responses against the body's own tissues.

8 Jan 2020

Persistent TB infection of macrophages puts the brakes on immune engines, study shows

Scientists from Trinity College Dublin have discovered both how TB puts the brakes on our immune engines and how we can kick-start those engines back into gear - providing hope that improved treatment options could soon be on the horizon.

8 Jan 2020

Research adds definitive evidence about how the body's earliest immune cells are formed

One day the advance could lead to a patient's own skin cells being used to produce new cells for cancer immunotherapy or to test autoimmune disease interventions.

8 Jan 2020

New ACMG Points to Consider document on use of fetal exome sequencing in prenatal care

A new Points to Consider document from the ACMG aims to assist referring physicians, laboratory geneticists, genetic counselors and other medical professionals in understanding the complexity and implications of exome sequencing in prenatal care.

8 Jan 2020

Palmetto GBA now covers Genomic Testing Cooperative’s solid tumor molecular profile

Genomic Testing Cooperative, LCA announced that the Medicare Administrative Contractor Palmetto GBA (MolDx) has established coverage for its solid tumor molecular profile.

7 Jan 2020

Hobbyist DNA services may be vulnerable to genetic hacking

Online services that allow users to upload their genetic information, research genealogy and find lost relatives may be vulnerable to a sort of genetic hacking, according to two geneticists at the University of California, Davis. A paper describing the work is published Jan. 7 in the journal eLife.

7 Jan 2020

Life Science News

So test therefore, who join …

Missing a key protein in the brain can cause autism-like behaviors

First-ever genomic analysis of puberty yields insights into critical areas of human health

Common genetic defect in prostate cancer associated with worse prognosis

Scientists find way to combine two main coding languages into single 'bilingual' molecule

Insect leaf-wounding produces healthier organic fruit

Scientists discover how bacterial evolution of antibiotic arsenals is providing new drug blueprints

Research reveals cardiac thin filament structure and function

Researchers identify synergistic cellular pathways that considerably amplify lifespan

ERS Genomics and New England Biolabs sign agreement to commercialize CRISPR/Cas9 tools, reagents

Avacta and Daewoong Pharmaceutical announce joint venture to develop novel cell and gene therapies

New screening platform helped scientists to discover drug-like compounds

Researchers report first structural model for key enzyme associated with inherited eye diseases

Researchers use single cell genome sequencing to study malaria transmission

Scientists discover how dying cells prevent dangerous immune reactions

Persistent TB infection of macrophages puts the brakes on immune engines, study shows

Research adds definitive evidence about how the body's earliest immune cells are formed

New ACMG Points to Consider document on use of fetal exome sequencing in prenatal care

Palmetto GBA now covers Genomic Testing Cooperative’s solid tumor molecular profile

Hobbyist DNA services may be vulnerable to genetic hacking

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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