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Insight into how cancer cells acquire selective survival advantage

Research led by David Litchfield of The University of Western Ontario has identified how biochemical pathways can be "rewired" in cancer cells to allow these cells to ignore signals that should normally trigger their death. It's one way that cancer cells may become resistant to therapy.

9 Jun 2011

Poplar bud extracts can serve as good source of antioxidants for skin creams

Antioxidants are popular anti-aging ingredients in skin creams, and now scientists are reporting a new source of these healthful substances - leaf buds of poplar trees. Their study appears in the ACS' Journal of Agricultural and Food Chemistry.

9 Jun 2011

Decline of citrate concentration may contribute to bone brittleness

Bone is one of nature's surprising "building materials." Pound-for-pound it's stronger than steel, tough yet resilient. Scientists at the U.S. Department of Energy's Ames Laboratory have identified the composition that gives bone its outstanding properties and the important role citrate plays, work that may help science better understand and treat or prevent bone diseases such as osteoporosis.

9 Jun 2011

Adjuvant combination generates memory CD8 T cells which could kill infected cells

Researchers at National Jewish Health have discovered how to prime a second arm of the immune system to potentially boost influenza vaccine effectiveness. A combination of two adjuvants, chemicals used to boost the effectiveness of some vaccines, induced CD8, or killer, T cells to join antibodies in response to influenza infection.

9 Jun 2011

Neurologix reports new results from NLX-P101 Phase 2 trial against Parkinson's disease

Neurologix, Inc. announced today several new results from the Company's successful Phase 2 clinical trial for its novel, investigational gene therapy NLX-P101 for the treatment of Parkinson's disease (PD) as part of a comprehensive presentation of study findings to the National Institutes of Health (NIH) Recombinant DNA Advisory Committee.

9 Jun 2011

GHI releases country strategies guidance

The GHI recently released its Guidance for Global Health Initiative Country Strategies.

9 Jun 2011

Eliminating ABCB5-expressing cells crucial for successful colorectal cancer treatment

Researchers at Children's Hospital Boston have found a marker called ABCB5 that both tags a small proportion of cells within colorectal cancers and fuels resistance in those cells to standard treatments. The results indicate that eliminating ABCB5-expressing cells is crucial for successful colorectal cancer treatment, while adding to the growing body of evidence for a theory of cancer growth called the cancer stem cell hypothesis.

9 Jun 2011

Medical management preferred over surgery for pediatric orbital cellulitis

Researchers from Hasbro Children's Hospital in Providence, R.I., report that medical management may be preferred over surgery for children with orbital cellulitis, an acute infection of the tissues surrounding the eye. They have determined the criteria for surgical intervention should be dependent upon the size of a subperiosteal abscess (SPA).

9 Jun 2011

Tips for preventing heat-related illnesses

With record-breaking temperatures expected in the Northeast and hot and humid conditions in the South, heat-related illnesses are to be expected. UAB emergency medicine doctors have tips to stay safe.

9 Jun 2011

Study: Many employers will cut back on health plans when overhaul kicks in

A report by McKinsey & Co. concluded that at least 30 percent of employers will stop offering health insurance in 2014. The projection is based on a survey of more than 1,300 businesses of various sizes and industries.

9 Jun 2011

Key molecule of vascular system directs axons during neural circuit formation

Dr. Fr-d-ric Charron, researcher at the Institut de recherches cliniques de Montr-al (IRCM), and his team have shown for the first time that a key molecule of the vascular system directs axons during the formation of neural circuits.

9 Jun 2011

Early parental emotional abuse linked to higher number of sleep complaints in old age

Suffering from parental abuse as a child increases a person's chances of having poor sleep quality in old age, according to a research article in the current issue of the Journals of Gerontology Series B: Psychological and Social Sciences.

9 Jun 2011

Emphysema gene linked to lung cancer

A gene linked to emphysema also can be a factor for developing lung cancer unrelated to cigarette smoking, UT Southwestern Medical Center research indicates. Smoking was the only known risk factor previously associated with both diseases.

9 Jun 2011

High-fat diet may cause brain nerve cell injury

Obesity among people who eat a high-fat diet may involve injury to neurons, or nerve cells, in a key part of the brain that controls body weight, according to the authors of a new animal study. The results will be presented Tuesday at The Endocrine Society's 93rd Annual Meeting in Boston.

9 Jun 2011

State roundup: N.J. plan would cut Medicaid by $500 million

States and territories are eligible for up to $40 million to strengthen and coordinate efforts to prevent chronic disease, the Health and Human Services Department announced Tuesday. The initiative is funded by the healthcare reform law and targets the nation's five leading chronic diseases: heart disease, cancer, stroke, diabetes and arthritis.

9 Jun 2011

Eli Lilly receives favorable U.S. District Court ruling in Amylin litigation

Eli Lilly and Company today announced that the U.S. District Court for the Southern District of California ruled in Lilly's favor, vacating a temporary restraining order and denying a request by Amylin Pharmaceuticals for a preliminary injunction that sought to impose restrictions on the Lilly Diabetes sales force and other relief.

9 Jun 2011

Yikes! 5,085 kilojoules and 80.5 grams of fat in one burger

After the naming of a Hungry Jack's burger as the unhealthiest in the nation, all state governments are planning to introduce legislation requiring fast food outlets to list the energy content on their menus.

9 Jun 2011

Rockefeller, Scripps Research develop first genetically humanized mouse model for hepatitis C

Scientists at Rockefeller University and The Scripps Research Institute have developed the first genetically humanized mouse model for hepatitis C, an achievement that will enable researchers to test molecules that block entry of the hepatitis C virus into cells as well as potential vaccine candidates. The finding is reported in the June 9 issue of the journal Nature.

9 Jun 2011

Longer surgery waiting lists in NSW: report

According to a new state health report, people in NSW are waiting longer for elective surgery than two years ago. For the report the Bureau of Health Information analyzed 46,500 elective surgeries carried out in NSW public hospitals between January and March this year.

9 Jun 2011

Drug that makes the failing heart heal itself

Researchers have found that a drug can heal heart muscles in mice. Earlier it was considered that this damage to the heart is permanent but this new findings refutes earlier beliefs.

9 Jun 2011