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Bayer's radium-223 chloride Phase III trial in CRPC, bone metastases meet primary endpoint

Bayer HealthCare Pharmaceuticals Inc. today announced that the Phase III ALSYMPCA trial evaluating Bayer's investigational compound, radium-223 chloride, which is exclusively licensed from Algeta ASA, in patients with castration-resistant prostate cancer (CRPC) and bone metastases met its primary endpoint by significantly improving overall survival.

6 Jun 2011

Topiramate drug can help people lose weight

The drug topiramate can help people lose weight as long as they can tolerate the side effects, according to authors of a new study that reviewed the medical literature. Brazilian researchers will present the results Saturday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

ImmunoGen's IMGN901 Phase I trial data on multiple myeloma presented at ASCO 2011

ImmunoGen, Inc., a biotechnology company that develops targeted antibody-based anticancer products using its antibody expertise and Targeted Antibody Payload (TAP) technology, today announced positive clinical data with the Company's IMGN901 (lorvotuzumab mertansine) product candidate as featured in an oral presentation at the ASCO 2011 Annual Meeting in Chicago.

6 Jun 2011

Study examines disparities in physical fitness levels between two groups

An Indiana University study examining disparities in physical fitness levels between older adults who are patients of safety net community health centers (CHC) and those who are members of a medically affiliated fitness center is producing stunning results.

6 Jun 2011

Incyte's ruxolitinib Phase III trial data on myelofibrosis presented at ASCO 2011

Incyte Corporation announced today results from the global, pivotal Phase III clinical program of ruxolitinib in patients with myelofibrosis (MF) at the 2011 American Society of Clinical Oncology (ASCO) Annual Meeting.

6 Jun 2011

Women with breast cancer do not benefit from flaxseed

Flaxseed provides no benefit in easing hot flashes among breast cancer patients and postmenopausal women, according to a Mayo Clinic and North Central Cancer Treatment Group study.

6 Jun 2011

Formoterol medication shows promise for improving fat and protein metabolism in men

Formoterol, a new generation asthma medication, shows great promise for improving fat and protein metabolism, say Australian researchers, who have tested this effect in a small sample of men. The researchers presented their results on Saturday 4 June 2011 at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

Bristol-Myers Squibb's second YERVOY Phase 3 trial on metastatic melanoma meets primary endpoint

Bristol-Myers Squibb Company today announced results from a second Phase 3 randomized, double blind study demonstrating that YERVOY (ipilimumab) prolonged the lives of patients with metastatic melanoma.

6 Jun 2011

Women with ovarian cancer do not benefit from CA-125 and transvaginal ultrasound

In a clinical trial that included nearly 80,000 women, those who received ovarian cancer screening did not have a reduced risk of death from ovarian cancer compared to women who received usual care, but did have an increase in invasive medical procedures and associated harms as a result of being screened, according to a study in the June 8 issue of JAMA, a theme issue on cancer.

6 Jun 2011

Ipsen decides to assess development of Irosustat in combination with hormonal therapies

Ipsen today announced its decision to assess the alternative development of Irosustat (BN 83495) in combination with other hormonal therapies. This decision is based on the futility analysis from the proof-of-concept trial phase II clinical study carried out in Europe in monotherapy in endometrial cancer, and on the phase I/II clinical study results obtained in metastatic prostate and breast cancers.

6 Jun 2011

Promising results from Exelixis' cabozantinib phase 2 trial against metastatic ovarian cancer

Exelixis, Inc. reported longer follow-up data from a fully enrolled cohort of patients with advanced epithelial ovarian cancer, primary peritoneal carcinoma, or fallopian tube carcinoma treated with cabozantinib (XL184) in an ongoing phase 2 adaptive randomized discontinuation trial. Cabozantinib shows promising activity in these patients independent of prior response to platinum-based therapies.

6 Jun 2011

ImaginAb, GE Healthcare sign master research deal to develop new PET diagnostic imaging agents

GE Healthcare Ltd. and ImaginAb, Inc. have executed a master research agreement around the development of new PET (Positron Emission Tomography) diagnostic imaging agents based on ImaginAb's antibody fragment technology. The agreement is launched with an initial exclusive collaboration around a novel cardiovascular target.

6 Jun 2011

GP journal focuses on mental health

Australian Family Physician, the flagship journal of The Royal Australian College of General Practitioners (RACGP), features a range of clinical, viewpoint and research articles focusing on key issues in general practice today. The June 2011 edition focuses on mental illness and includes the following feature articles.

6 Jun 2011

Low-cost healthy lifestyle program can prevent excess weight gain in pregnant women

A new study reports that a low-cost healthy lifestyle program, including self-weighing weekly or monthly, by pregnant women with pre-existing overweight can prevent them from gaining too much weight during early pregnancy. The researchers will present the results Sunday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

Older adults with subclinical hyperthyroidism may face higher risk of dying

A common hormone abnormality in older adults—a mild form of overactive thyroid called subclinical hyperthyroidism—is linked to a much higher risk of dying, a new study finds. The results will be presented Sunday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

ImmunoGen's SAR3419 Phase I trial data on B-cell non-Hodgkin's lymphoma presented at ASCO 2011

ImmunoGen, Inc., a biotechnology company that develops targeted antibody-based anticancer products using its antibody expertise and Targeted Antibody Payload (TAP) technology, today announced the presentation of favorable clinical data for SAR3419 in the treatment of B-cell non-Hodgkin's lymphoma (NHL).

6 Jun 2011

NYU Langone Medical Center achieves historic and unprecedented philanthropic milestone

NYU Langone Medical Center announced that it has reached a historic and unprecedented philanthropic milestone, raising $1 billion in less than four years.

6 Jun 2011

Bharat Biotech announces the pricing for ROTAVAC vaccine

Bharat Biotech today announced the price of ROTAVAC India’s first indigenously developed Rotavirus Vaccine. The vaccine will be sold to global public markets, Governments worldwide including UN procurement agencies at a price of US $ 1.0. Bharat Biotech hopes its new vaccine will help prevent part of the ~ 500,000 child deaths each year caused due to rotavirus diarrhea and improve access to better, affordable rotavirus vaccines.

6 Jun 2011

Brown fat can treat obesity and diabetes

A new study suggests that many adults have large amounts of brown fat, the "good" fat that burns calories to keep us warm, and that it may be possible to make even more of this tissue.

6 Jun 2011

Study links exposure to BPA with lowered male fertility

Daily exposure to a chemical that is prevalent in the human environment, bisphenol A (BPA), causes lowered fertility in male mice, according to the results of a new study that will be presented Saturday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

Medical News

Bayer's radium-223 chloride Phase III trial in CRPC, bone metastases meet primary endpoint

Topiramate drug can help people lose weight

ImmunoGen's IMGN901 Phase I trial data on multiple myeloma presented at ASCO 2011

Study examines disparities in physical fitness levels between two groups

Incyte's ruxolitinib Phase III trial data on myelofibrosis presented at ASCO 2011

Women with breast cancer do not benefit from flaxseed

Formoterol medication shows promise for improving fat and protein metabolism in men

Bristol-Myers Squibb's second YERVOY Phase 3 trial on metastatic melanoma meets primary endpoint

Women with ovarian cancer do not benefit from CA-125 and transvaginal ultrasound

Ipsen decides to assess development of Irosustat in combination with hormonal therapies

Promising results from Exelixis' cabozantinib phase 2 trial against metastatic ovarian cancer

ImaginAb, GE Healthcare sign master research deal to develop new PET diagnostic imaging agents

GP journal focuses on mental health

Low-cost healthy lifestyle program can prevent excess weight gain in pregnant women

Older adults with subclinical hyperthyroidism may face higher risk of dying

ImmunoGen's SAR3419 Phase I trial data on B-cell non-Hodgkin's lymphoma presented at ASCO 2011

NYU Langone Medical Center achieves historic and unprecedented philanthropic milestone

Bharat Biotech announces the pricing for ROTAVAC vaccine

Brown fat can treat obesity and diabetes

Study links exposure to BPA with lowered male fertility

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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