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Almac's main research projects on ovarian, breast cancer to be presented at ASCO 2011

Two of Almac's main research projects have been selected for presentation at the 2011 ASCO meeting. Both of these studies are based on Almac's approach of profiling large clinical datasets and analysing the data for molecular subgroups that can aid in improved diagnosis of cancer by identifying molecular subtypes and by identifying molecular subgroups which are of clinical and therapeutic relevance.

31 May 2011

Scientists develop carbohydrate-based vaccine against C. difficile infection

There is now a promising vaccine candidate for combating the pathogen which causes one of the most common and dangerous hospital infections. An international team of scientists from the Max Planck Institute of Colloids and Interfaces in Potsdam has developed a vaccine based on a carbohydrate against the Clostridium difficile bacterium, which is known to cause serious gastrointestinal diseases mainly in hospitals.

31 May 2011

Heptares, AstraZeneca partner to discover and develop new GPCR drug targets

AstraZeneca and Heptares Therapeutics today announced they have entered a four-year collaboration focused on the potential discovery and development of new medicines targeting G-protein coupled receptors.

31 May 2011

Scientists study key malaria protein structure to demonstrate how cells grow and move

Researchers from the Walter and Eliza Hall Institute have overturned conventional wisdom on how cell movement across all species is controlled, solving the structure of a protein that cuts power to the cell 'motor'. The protein could be a potential drug target for future malaria and anti-cancer treatments.

31 May 2011

Annual meeting of Society for Prevention Research to be held in Washington, DC

The mass shooting in Tucson that left six people dead and many more injured, including Congresswoman Gabrielle Giffords, brought significant attention to availability, accessibility and quality of treatment services for serious mental, emotional and behavioral disorders and substance abuse.

31 May 2011

Study finds novel site within MS4A gene cluster, confirms presence of SNP linked with Alzheimer's

Recently the number of genes known to be associated with Alzheimer's disease has increased from four to eight, including the MS4A gene cluster on chromosome 11.

31 May 2011

Cancer drug helps prevent hypertensive heart disease

A promising cancer treatment drug can restore function of a heart en route to failure from high blood pressure, researchers at UT Southwestern Medical Center have found.

31 May 2011

EpiCept completes $10.6 million 11.5% senior secured term loan facility with MidCap Financial

EpiCept Corporation today announced that it has completed a $10.6 million 11.5% senior secured term loan facility with MidCap Financial LLC.

31 May 2011

Functional MRI acquired during speech stimulation predicts children with autism

Functional magnetic resonance imaging may provide an early and objective indicator of autism, according to researchers at Columbia University in New York City, who used the technique to document language impairment in autistic children.

31 May 2011

CMAJ report outlines challenges, approaches to manage and identify NDM-1 antibiotic resistant enzyme

An enzyme associated with extensive antibiotic resistance called New Delhi metallo---lactamase-1 (NDM-1), endemic in India and Pakistan and spreading worldwide, has been found in two people in the Toronto area, one of whom acquired it in Canada, states a case report in CMAJ.

31 May 2011

Small noncoding RNA spurs Alzheimer's development

Researchers pinpoint a small RNA that spurs cells to manufacture a particular splice variant of a key neuronal protein, potentially promoting Alzheimer's disease or other types of neurodegeneration.

31 May 2011

Koreans show positive attitude towards end-of-life care for cancer patients: Study

Attitudes toward end-of-life care for cancer patients vary, but most patients, family members, oncologists and members of the public are receptive to withdrawing futile life-sustaining treatments in people who are dying, found a Korean study in CMAJ.

31 May 2011

Study: E-waste linked to adverse effects on human health

In addition to its damaging effect on the environment and its illegal smuggling into developing countries, researchers have now linked e-waste to adverse effects on human health, such as inflammation and oxidative stress - precursors to cardiovascular disease, DNA damage and possibly cancer.

31 May 2011

Stress does not appear to increase risk of developing multiple sclerosis

Contrary to earlier reports, a new study finds that stress does not appear to increase a person's risk of developing multiple sclerosis. The research is published in the May 31, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology.

31 May 2011

Some Veterans' health jeopardized due to poor infection control

Herman Williams came home safely after fighting in the jungles of Vietnam as a Marine. He was shocked to learn four decades later that his military service had again placed him in jeopardy — this time, because he got a tooth pulled. Williams is among 13,000 U.S. veterans who have been warned in the last two years that their blood should be tested for potentially fatal infections after possible exposures by improper hygiene practices at five VA hospitals in Ohio, Florida, Georgia, Missouri and Tennessee.

31 May 2011

Mouse Phylogeny Viewer

Laboratory research has always been limited in terms of what conclusions scientists can safely extrapolate from animal experiments to the human population as a whole. Many promising findings in mice have not held up under further experimentation, in part because laboratory animals, bred from a limited genetic foundation, don't provide a good representation of how genetic diversity manifests in the broader human population.

30 May 2011

Improvements to Medicare prescription drug program benefit MS patients in the 'donut hole'

As the average cost of MS in the United States is nearly $70,000 a year, with the overall annual economic cost of MS being an estimated $28 billion, people living with MS face high out-of-pocket costs even when covered by health insurance.

30 May 2011

Positive results from DavosLife Natural e3 phase I clinical trial in resectable pancreatic cancer

Davos Life Science has today announced preliminary results of a phase I clinical trial of its Natural e3 delta-tocotrienol (Natural e3) in patients with resectable pancreatic cancer. Tocotrienols are highly potent members of the Vitamin E family that have been found by researchers to inhibit the growth and survival of various types of cancer cells.

30 May 2011

Canadian women more aware of ovarian cancer now, but misconceptions remain

Canadian women know more about ovarian cancer than they did six years ago, but misconceptions remain that could lead to late diagnosis of the country's most fatal gynecologic cancer - a disease that claims the lives of 70% of those diagnosed.

30 May 2011

Complementary technologies for rapid EHEC identification and detection

With the recent outbreak in Europe of Enterohaemorrhagic Escherichia coli (EHEC), Roche Applied Science and TIB Molbiol are providing scientists with complementary technologies that can be used for the rapid identification and detection of EHEC.

30 May 2011

Medical News

Almac's main research projects on ovarian, breast cancer to be presented at ASCO 2011

Scientists develop carbohydrate-based vaccine against C. difficile infection

Heptares, AstraZeneca partner to discover and develop new GPCR drug targets

Scientists study key malaria protein structure to demonstrate how cells grow and move

Annual meeting of Society for Prevention Research to be held in Washington, DC

Study finds novel site within MS4A gene cluster, confirms presence of SNP linked with Alzheimer's

Cancer drug helps prevent hypertensive heart disease

EpiCept completes $10.6 million 11.5% senior secured term loan facility with MidCap Financial

Functional MRI acquired during speech stimulation predicts children with autism

CMAJ report outlines challenges, approaches to manage and identify NDM-1 antibiotic resistant enzyme

Small noncoding RNA spurs Alzheimer's development

Koreans show positive attitude towards end-of-life care for cancer patients: Study

Study: E-waste linked to adverse effects on human health

Stress does not appear to increase risk of developing multiple sclerosis

Some Veterans' health jeopardized due to poor infection control

Mouse Phylogeny Viewer

Improvements to Medicare prescription drug program benefit MS patients in the 'donut hole'

Positive results from DavosLife Natural e3 phase I clinical trial in resectable pancreatic cancer

Canadian women more aware of ovarian cancer now, but misconceptions remain

Complementary technologies for rapid EHEC identification and detection

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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