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Brookside Surgery Center to participate in iUni G2 knee implant trial

Dr. Joseph Burkhardt of Brookside Surgery Center is participating in a ten year follow-up trial of the ConforMIS iUni G2 knee resurfacing device, an FDA cleared implant for patients with osteoarthritic damage in a single compartment of the knee.

27 Apr 2011

Rxi secures SBIR grants to develop novel RNAi therapeutics for ALS

RXi Pharmaceuticals Corporation, a biotechnology company focused on discovering, developing and commercializing innovative therapies addressing major unmet medical needs using RNA-targeted and immunotherapy technologies, today announced that it was awarded two Small Business Innovation Research grants from the National Institutes of Health.

27 Apr 2011

Study links readmissions with nurse overtime

Fewer patients returned to the hospital soon after leaving when hospitals reduced nurse overtime, according to a newly released study. The research, published in the journal Health Services Research, analyzed records for roughly 1,900 patients at four hospitals during the first half of 2008.

27 Apr 2011

Positive results from Sanofi-aventis and Regeneron ZALTRAP Phase III study in mCRC

Sanofi-aventis and Regeneron Pharmaceuticals, Inc. announced that the Phase III VELOUR trial evaluating the investigational agent ZALTRAP, also known as VEGF Trap, in combination with the FOLFIRI chemotherapy regimen versus a regimen of FOLFIRI plus placebo met its primary endpoint of improving overall survival in the second-line treatment of metastatic colorectal cancer.

27 Apr 2011

Heparan sulfate may have a key role in tumor-spurred lymphatic vessel growth

Cancer has a mighty big bag of tricks that it uses to evade the body's natural defense mechanisms and proliferate. Among those tricks is one that allows tumor cells to turn the intricate and extensive system of lymphatic vessels into something of a highway to metastasis. Yet research unveiled this week may aid in the development of therapeutics that will put the brakes on such cancer spread, and the researchers who completed the study say the findings may extend to other lymphatic disorders.

27 Apr 2011

Researchers develop protein-based inhibitor that can treat HPV

Human papillomavirus causes cervical cancer, the second most common cause of cancer death for women, and is a common cause of anogenital and some head and neck cancers.

27 Apr 2011

Bioengineering students invent life-saving heart device

An invention by Rice University bioengineering students in collaboration with the Texas Heart Institute is geared toward giving immediate second chances to arrhythmia victims headed toward cardiac arrest.

27 Apr 2011

ISC-4 topical compound may prevent skin cancer lesion formation

While incidents of melanoma continue to increase despite the use of sunscreen and skin screenings, a topical compound called ISC-4 may prevent melanoma lesion formation, according to Penn State College of Medicine researchers.

27 Apr 2011

Cholesterol-lowering drugs may help clot-busting drugs treat strokes

Cholesterol-lowering drugs known as statins may help clot-busting drugs treat strokes, according to researchers at Washington University School of Medicine in St. Louis.

27 Apr 2011

Azithromycin holds promise for preventing BPD in Ureaplasma-infected preterm infants

A study performed by University of Kentucky researchers shows promise for the use of azithromycin in treating Ureaplasma-colonized or infected premature infants to prevent bronchopulmonary dysplasia (BPD).

27 Apr 2011

State roundup: Single-payer bill advances in Vt. Legislature

A unit of American International Group, the New York-based insurance giant, agreed to pay restitution and a fine totaling $760,000 for selling faulty health insurance products in Massachusetts, under a settlement reached with state Attorney General Martha Coakley.

27 Apr 2011

IQ Therapeutics completes dosing in IQNLF Phase I trial for anthrax

IQ Therapeutics has completed the dosing of antibody IQNLF in a Phase I clinical trial. A total of 36 healthy volunteers participated in the randomized, placebo controlled, double blind, single dose-escalating study, intended to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of IQNLF.

27 Apr 2011

VeraLight's Scout DS Device receives Health Canada License approval

VeraLight Inc., a privately held medical device company, based here, today announced its Scout DS Device was granted a Health Canada Medical Device Licence for non-invasive diabetes screening.

27 Apr 2011

Magnetic 'nanobeads' help detect chemical and biological agents

Researchers at Oregon State University have found a way to use magnetic "nanobeads" to help detect chemical and biological agents, with possible applications in everything from bioterrorism to medical diagnostics, environmental monitoring or even water and food safety.

27 Apr 2011

Tarix begins patient enrollment for TXA127 Phase 1 study in DCBT

Tarix Pharmaceuticals today announced enrollment of the first patient in a Phase 1 clinical study of TXA127, a pharmaceutical grade formulation of a naturally occurring peptide known to stimulate early hematopoietic precursor cells in the bone marrow.

27 Apr 2011

Columbia requests FDA Priority Review for PROCHIEVE progesterone gel NDA

Columbia Laboratories, Inc., and Watson Pharmaceuticals, Inc., today announced that Columbia has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for PROCHIEVE® (progesterone gel) for the reduction of risk of preterm birth in women with short uterine cervical length in the mid-trimester of pregnancy.

27 Apr 2011

Acousticon receives FDA 510K clearance for ACAM-5 integrated hearing loss assessment system

Acousticon Inc., the US subsidiary of Acousticon GmbH announced today that they have received FDA 510K clearance for ACAM-5®, a German-engineered, stand-alone system containing an audiometer integrated with Real Ear Measurement (REM), and Hearing Instrument Test (HIT) modules.

27 Apr 2011

Vitamin D levels may help explain racial disparities in hypertension

Lower vitamin D levels may explain part of the disparity in hypertension that exists between Black and White people in the US. High blood pressure is more common in Blacks than in Whites and persons with darker skin generally produce less vitamin D.

27 Apr 2011

AAN honors BIDMC neurologist with Epilepsy Award

Bernard Chang, MD, a member of the Department of Neurology at Beth Israel Deaconess Medical Center and Assistant Professor of Neurology at Harvard Medical School, received the Dreifuss-Penry Epilepsy Award at the 63rd Annual Meeting of the American Academy of Neurology, held recently in Honolulu, HI.

27 Apr 2011

Motor regulatory protein can block human ovarian tumor growth

A motor regulatory protein can block human ovarian tumor growth, leading to eventual cancer cell death and possible new therapies to treat the disease, according to Penn State College of Medicine researchers.

27 Apr 2011