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Illumina announces next generation of iSelect custom genotyping products

Illumina, Inc. today announced its next generation of iSelect custom genotyping products that allow researchers to design custom arrays containing from 3,000 up to 1,000,000 markers, with the flexibility to add supplemental content to their array designs.

From Illumina, Inc. 10 Jan 2011

FDA grants Exelixis XL184 orphan drug designation for treatment of medullary thyroid cancer

Exelixis, Inc. today announced that the U.S. Food & Drug Administration (FDA) has granted orphan drug designation to XL184 for treatment of follicular, medullary, and anaplastic thyroid carcinoma, and metastatic or locally advanced papillary thyroid cancer. A pivotal phase 3 trial of XL184 is ongoing in patients with medullary thyroid cancer (MTC) and the company expects to release top-line phase 3 results in the first-half of 2011 and potentially file a New Drug Application (NDA) for the compound in the second-half of 2011.

10 Jan 2011

First Edition: January 10, 2011

Health policy headlines include reports about the decision to delay the scheduled House vote on repealing the health law.

10 Jan 2011

KYTHERA and Intendis initiate ATX-101 European Phase III studies for reduction of submental fat

KYTHERA Biopharmaceuticals, Inc. and Intendis, Bayer HealthCare's dermatology business, today announced the initiation of two European Phase III studies evaluating ATX-101, a first-in-class injectable adipolytic agent, for the reduction of localized fat under the chin (submental fat).

10 Jan 2011

LabCorp to market On-Q-ity's circulating tumor cell platform

On-Q-ity, a next-generation oncology diagnostics company developing personalized and predictive tests to improve cancer therapy effectiveness, today announced a strategic alliance with Laboratory Corporation of America Holdings® (LabCorp). LabCorp will market On-Q-ity's novel and proprietary circulating tumor cell (CTC) platform to the biopharma industry to greatly accelerate and improve the cancer drug discovery and development process.

10 Jan 2011

Researchers describe crucial initial steps taken by measles virus attachment proteins with receptors

Mayo Clinic researchers have shown that proteins on the surface of a cell twist a viral protein into position, allowing the virus to start infection and cause disease, all in a movement as graceful as a ballroom dance. The findings appear in the current online issue of Nature Structural & Molecular Biology.

10 Jan 2011

New study finds extending term of exclusive access can lead to higher drug costs in short term

A new study in the January 2011 issue of Health Affairs is the first to calculate the financial and social costs of limiting access to trial data — and finds that extending the term of exclusive access will lead to higher drug costs in the short term but also to more than 200 extra drug approvals and to greater life expectancy in the next several decades.

10 Jan 2011

Food price rise will affect 'millions,' FAO economist says

Abdolreza Abbassian, an economist with the U.N. Food and Agriculture Organization (FAO), on Friday "warned of a 'worrying rise' in food prices which will affect millions of people following unexpected shortfalls in major cereals owing to bad weather in 2010," Agence France-Presse reports.

10 Jan 2011

Slowing engines of mitochondria could extend life

In making your pro-longevity resolutions, like drinking more red wine and maintaining a vibrant social network, here's one you likely forgot: dialing down your mitochondria. It turns out that slowing the engines of these tiny cellular factories could extend your life-an observation relevant not only to aging research but to our understanding of how cells communicate with each another.

10 Jan 2011

Hospice of Michigan offers toolkit to help people on end-of-life decision making and planning

Hospice of Michigan offers a complete toolkit to empower individuals and families to take control of end-of-life decision making and planning. The free resource is the www.haveyouhadthetalk.org website from which a toolkit can be downloaded and printed for free.

10 Jan 2011

Colorectal cancer screening disparities in certain regions

Individuals from certain areas of the United States are more likely to get screened for colorectal cancer than those from other areas, particularly when comparing non-whites living in different parts of the country. That is the conclusion of a new study published early online in Cancer, a peer-reviewed journal of the American Cancer Society. Additional research is needed to better understand how colorectal cancer screening disparities develop in some regions and not in others.

10 Jan 2011

Positive preclinical results from Inovio's novel DNA vaccine targeting HIV Clade C virus

Inovio Pharmaceuticals, a leader in the development of therapeutic and preventive vaccines against cancers and infectious diseases, announced today the publication of a scientific paper highlighting positive preclinical results from Inovio's novel DNA vaccine targeting HIV Clade C viruses in the journal Vaccine.

10 Jan 2011

U.N. announces members of independent panel to investigate source of Haiti's cholera epidemic

U.N. Secretary-General Ban Ki-moon announced the names of four experts to be part of an independent panel that will "investigate the source of Haiti's cholera epidemic, which some Haitians blame on U.N. peacekeepers," Reuters reports (Worsnip, 1/6). "The members of the panel have been selected based on their global stature, expertise and extensive experience working with cholera in all its aspects," according to a statement from Ban's spokesperson, U.N. News Centre reports (1/6).

10 Jan 2011

AMT enters agreement with Consortium for clinical development of novel gene therapy to treat Sanfilippo B

Amsterdam Molecular Therapeutics, a leader in human gene therapy, announced today that it has entered into an agreement with Institut Pasteur, Paris, France, and a group of French research institutes (together the "Consortium") to support clinical development of a novel gene therapy to treat Sanfilippo B.

10 Jan 2011

Endo Pharmaceuticals receives FDA complete response letter for OPANA ER

Endo Pharmaceuticals today announced that it received a complete response letter from the U.S. Food and Drug Administration regarding the New Drug Application for its new formulation of OPANA® ER designed to be crush resistant.

10 Jan 2011

Quality of life measures most useful for clinical decision-making in trials with QOL as primary outcome

Quality of life measures tend to be most useful for clinical decision-making in trials in which quality of life is the primary outcome, according to a recent study published online January 7 in The Journal of the National Cancer Institute.

10 Jan 2011

Miracor’s PICSO System may help advance heart failure treatment

Miracor Medical Systems GmbH announced today that its PICSO® (Pressure-controlled Intermittent Coronary Sinus Occlusion) System, designed to improve outcomes for acute coronary syndrome (ACS) and heart failure patients, has been cited as a technology that "may advance heart failure (HF) treatment significantly".

10 Jan 2011

HHS grants $10 million fund for HCPG opportunity

HHS Secretary Kathleen Sebelius today announced up to $10 million in funding for a Health Center Planning Grant opportunity for organizations across the country that would like to become a Community Health Center.

10 Jan 2011

Resveratrol stimulates expression of adiponectin hormone: Study

Resveratrol, a compound in grapes, displays antioxidant and other positive properties. In a study published this week, researchers at the UT Health Science Center San Antonio describe a novel way in which resveratrol exerts these beneficial health effects.

10 Jan 2011

New mechanisms of resistance to chemotherapy among leukemia patients

The interplay between a major tumor-suppressing gene, a truncated chromosome and two sets of microRNAs provides a molecular basis for explaining the less aggressive form of chronic lymphocytic leukemia, an international team of researchers reports today in the Jan. 4 edition of the Journal of the American Medical Association.

10 Jan 2011

Medical News

Illumina announces next generation of iSelect custom genotyping products

FDA grants Exelixis XL184 orphan drug designation for treatment of medullary thyroid cancer

First Edition: January 10, 2011

KYTHERA and Intendis initiate ATX-101 European Phase III studies for reduction of submental fat

LabCorp to market On-Q-ity's circulating tumor cell platform

Researchers describe crucial initial steps taken by measles virus attachment proteins with receptors

New study finds extending term of exclusive access can lead to higher drug costs in short term

Food price rise will affect 'millions,' FAO economist says

Slowing engines of mitochondria could extend life

Hospice of Michigan offers toolkit to help people on end-of-life decision making and planning

Colorectal cancer screening disparities in certain regions

Positive preclinical results from Inovio's novel DNA vaccine targeting HIV Clade C virus

U.N. announces members of independent panel to investigate source of Haiti's cholera epidemic

AMT enters agreement with Consortium for clinical development of novel gene therapy to treat Sanfilippo B

Endo Pharmaceuticals receives FDA complete response letter for OPANA ER

Quality of life measures most useful for clinical decision-making in trials with QOL as primary outcome

Miracor’s PICSO System may help advance heart failure treatment

HHS grants $10 million fund for HCPG opportunity

Resveratrol stimulates expression of adiponectin hormone: Study

New mechanisms of resistance to chemotherapy among leukemia patients

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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