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Ocular Therapeutix closes $14 million Series D financing round

Ocular Therapeutix, Inc. announced today that it has closed a $14 million Series D round of financing. The round was led by Ascension Health Ventures of St. Louis, Missouri, with continued participation by existing investors including Polaris Ventures, SV Life Sciences and Versant Ventures.

3 Feb 2011

Automation protocols for TruSeq kits is now available in Sciclone NGS Workstation

Caliper Life Sciences, today announced that it has developed and optimized automation protocols on its Sciclone NGS Workstation for Illumina's TruSeq DNA and TruSeq RNA sample preparation kits.

3 Feb 2011

Republicans advance plans for Senate vote on repealing health overhaul

The vote, which is likely to occur Wednesday, will be symbolic because Senate Democrats are confident they can defeat the GOP amendment in a procedural vote. But momentum continues to build regarding an effort to delete a small, revenue-raising provision of the sweeping law, which could cause its own wrinkles.

3 Feb 2011

Vegetarians, vegans need to increase omega-3 fatty acids and vitamin B12 to reduce heart disease risk

People who follow a vegan lifestyle - strict vegetarians who try to eat no meat or animal products of any kind - may increase their risk of developing blood clots and atherosclerosis or "hardening of the arteries," which are conditions that can lead to heart attacks and stroke. That's the conclusion of a review of dozens of articles published on the biochemistry of vegetarianism during the past 30 years.

3 Feb 2011

NIH awards CMU $1.2 million grant to analyze ethical, policy problems linked with DNA ID practices

Forensic DNA profiling has become a standard tool in the search for missing people in the aftermath of mass violence and disaster, but until now there has been very little effort to identify and analyze the major ethical and policy challenges associated with this new use of genetic technology.

3 Feb 2011

Largazole appears to be an ideal blueprint for developing new drugs against bone diseases

One of Mother Nature's latest gifts to medical science is stirring excitement with the discovery that the substance - obtained from a coral-reef inhabiting cyanobacterium - appears to be an ideal blueprint for developing new drugs for serious fractures, osteoporosis, and other bone diseases.

3 Feb 2011

SAGE Labs, Cofactor Genomics partner to sequence genomes for six widely used rat strains

Sigma Life Science, the innovative biological products and services business of Sigma-Aldrich®, today announced that its SAGE Labs initiative has partnered with Cofactor Genomics in an effort to sequence genomes for six of the most widely used strains of rat.

3 Feb 2011

LSU biochemists develop 5-LOX 3-D model to design effective asthma medication

Chronic inflammation has been directly associated with heart disease and other physical ailments. But LSU graduate student Nathanial Gilbert and Professor of Biological Sciences Marcia Newcomer, together with Associate Professor Sue Bartlett, have developed the first 3-D model of Human 5-Lipoxygenase, or 5-LOX, the molecule responsible for creating inflammatory compounds that provoke asthma.

3 Feb 2011

Study finds contradictory role of RIP1 protein in the liver during sepsis

Researchers from Rhode Island Hospital have identified a protein that plays a dual role in the liver during sepsis. The protein, known as RIP1, acts both as a "death switch" and as a pro-survival mechanism. The ability to identify the triggers for these functions may play a key role in treating sepsis in the future. The study is published online in advance of print in the journal Shock.

3 Feb 2011

Study: Health insurers consolidate market power

Meanwhile, Aetna mailed letters Tuesday to notify customers in Colorado that it will be exiting the individual market there.

3 Feb 2011

Malarial drugs may help treat specific form of frontotemporal dementia

Frontotemporal dementia is caused by a breakdown of nerve cells in the frontal and temporal region of the brain, which leads to, among other symptoms, a change in personality and behavior. The cause of some forms of frontotemporal dementia is a genetically determined reduction of a hormone-like growth factor, progranulin.

3 Feb 2011

Poor adolescents with strong community get protection from risky health behaviors

Children who grow up in poverty have health problems as adults. But a new study finds that poor adolescents who live in communities with more social cohesiveness and control get some measure of protection; they're less likely to smoke and be obese as adolescents.

3 Feb 2011

Agilent introduces first commercial RNA target enrichment system

Agilent Technologies, Inc., today introduced SureSelect RNA Capture Kits, the first commercial RNA target enrichment system enabling geneticists to focus on specific genomic loci or transcripts of research interest. The RNA capture kits make it possible to precisely measure expression levels of genes of interest and detect allelic-specific expression, splicing events and gene fusions.

3 Feb 2011

Four-gene/protein signature more accurately predicts metastatic prostate cancer

Prostate tumors that carry a "signature" of four molecular markers have the potential to become dangerously metastatic if not treated aggressively, researchers at Dana-Farber Cancer Institute report in a study published online today by the journal Nature. The discovery lays the groundwork for the first gene-based test for determining whether a man's prostate cancer is likely to remain dormant within the prostate gland, or spread lethally to other parts of the body.

3 Feb 2011

Older people with metabolic syndrome may face high risk of developing memory loss

Older people with larger waistlines, high blood pressure and other risk factors that make up metabolic syndrome may be at a higher risk for memory loss, according to a study published in the February 2, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

3 Feb 2011

Health law ruling draws different state reactions

State officials are sorting a legal decision issued Monday by a federal court judge in Florida overturning the health law. Their challenge is to determine how and whether to proceed with their implementation responsibilities. Some, like Florida's governor, appear to favor taking steps to stall its progress.

3 Feb 2011

Study uncovers genetic hierarchy in plant sperm formation

Biologists at the University of Leicester have published results of a new study into the intricacies of sex in flowering plants.

3 Feb 2011

Epocrates prices initial public offering at $16.00 per share

Epocrates, Inc. today announced the pricing of the initial public offering of 5,360,000 shares of its common stock at a price to the public of $16.00 per share. The shares are expected to begin trading today on the NASDAQ under the ticker symbol "EPOC." Epocrates is offering 3,574,285 shares and selling stockholders are offering the remaining 1,785,715 shares.

3 Feb 2011

Seattle Genetics prices underwritten public offering of 10,000,000 shares of common stock

Seattle Genetics, today announced the pricing of an underwritten public offering of 10,000,000 shares of its common stock, offered at a price to the public of $15.50 per share.

3 Feb 2011

Blue Shield of California agrees to postpone rate increase

With this announcement, Blue Shield joins other large California insurers — Anthem Blue Cross, Aetna and PacifiCare — in agreeing to the delay.

3 Feb 2011

Medical News

Ocular Therapeutix closes $14 million Series D financing round

Automation protocols for TruSeq kits is now available in Sciclone NGS Workstation

Republicans advance plans for Senate vote on repealing health overhaul

Vegetarians, vegans need to increase omega-3 fatty acids and vitamin B12 to reduce heart disease risk

NIH awards CMU $1.2 million grant to analyze ethical, policy problems linked with DNA ID practices

Largazole appears to be an ideal blueprint for developing new drugs against bone diseases

SAGE Labs, Cofactor Genomics partner to sequence genomes for six widely used rat strains

LSU biochemists develop 5-LOX 3-D model to design effective asthma medication

Study finds contradictory role of RIP1 protein in the liver during sepsis

Study: Health insurers consolidate market power

Malarial drugs may help treat specific form of frontotemporal dementia

Poor adolescents with strong community get protection from risky health behaviors

Agilent introduces first commercial RNA target enrichment system

Four-gene/protein signature more accurately predicts metastatic prostate cancer

Older people with metabolic syndrome may face high risk of developing memory loss

Health law ruling draws different state reactions

Study uncovers genetic hierarchy in plant sperm formation

Epocrates prices initial public offering at $16.00 per share

Seattle Genetics prices underwritten public offering of 10,000,000 shares of common stock

Blue Shield of California agrees to postpone rate increase

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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