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Pfizer announces publication of crizotinib data for NSCLC patients in New England Journal of Medicine

Pfizer Inc. announced today the publication of data showing that 57 percent of ALK-positive advanced non-small cell lung cancer (NSCLC) patients treated with crizotinib (PF-02341066), an investigational oral anaplastic lymphoma kinase (ALK) inhibitor, had either a complete (one patient) or partial (46 patients) response to treatment. Data from 82 patients in this Part 2 expansion cohort of the Phase 1 study were published in the October 28 issue of the New England Journal of Medicine.

28 Oct 2010

Researchers develop software tool to study wiring of brains

A team of researchers at the Eindhoven University of Technology has developed a software tool that physicians can use to easily study the wiring of the brains of their patients. The tool converts MRI scans using special techniques to three-dimensional images. This now makes it possible to view a total picture of the winding roads and their contacts without having to operate.

28 Oct 2010

AstraZeneca 2010 third quarter decreases 2% to $7,898 million

Anglo-Swedish pharmaceutical company AstraZeneca announced that revenue for the third quarter declined by 2% at constant exchange rates (CER) to $7,898 million.

28 Oct 2010

Disinfection cap dispensing 70% isopropyl alcohol effectively disinfects IV needleless connectors

A study and review performed by clinicians of PICC Excellence, Inc. found a disinfection cap that dispenses 70% isopropyl alcohol is effective in disinfecting IV needleless connectors after five minutes. The study shows that if a needleless connector is covered and bathed in alcohol by the disinfection cap, no drying time is required to kill nearly all pathogens on the connector.

28 Oct 2010

Scientists suggest FDA to reevaluate safety of plant-based antioxidants

Scientists are calling for more research on the possibility that some supposedly healthful plant-based antioxidants including those renowned for their apparent ability to prevent cancer may actually aggravate or even cause cancer in some individuals.

28 Oct 2010

Study examines children's tendencies toward food and development of obesity

When it comes to understanding where tendencies to overweight and obesity develop, you have to begin with the very young, says John Spence, a behavioural scientist in the Faculty of Physical Education and Recreation at the University of Alberta.

28 Oct 2010

Curemark adds two sites in California for CM-AT Phase III clinical trial program

Curemark, LLC, a drug research and development company focused on the treatment of neurological diseases, announced that it has added two sites in California to its Phase III clinical trial program for CM-AT, the company's autism treatment.

28 Oct 2010

Immune system may play a role in cancer therapies: Study

The immune system may play a critical role in ensuring the success of certain types of cancer therapies, according to a new study by researchers at the Stanford University School of Medicine. The research showed treatments that disable cancer-promoting genes called oncogenes are much more successful in eradicating tumors in the presence of a signaling molecule secreted by kind of immune cell called a T helper cell.

28 Oct 2010

Mirada Medical and Moffitt Cancer Center enter joint development agreement

Mirada Medical Limited, the fast growing international company focused on advanced oncology imaging, announced today that they have signed an agreement with Moffitt Cancer Center, Tampa, FL, one of the USA's top centers for cancer treatment and oncology research.

28 Oct 2010

Systemic amyloidosis patient to receive triple organ transplant

In 2005, then 40-year-old Walt McGuire was playing hockey twice a week, working full-time and chasing his young daughter. Then one day, he noticed after one trip up the stairs to catch her, he couldn't catch his breath. A few days later his legs were swollen. After numerous trips to different doctors, McGuire finally was diagnosed with a rare blood disorder called amyloidosis.

28 Oct 2010

Abbott provides $180,000 to support recent cholera outbreak in central Haiti

Abbott is providing $180,000 in support to help address the recent cholera outbreak in central Haiti. This includes a $25,000 grant from the Abbott Fund to Partners In Health, and $155,000 in donated Abbott rehydration solutions and antibiotics.

28 Oct 2010

Federal Government seizes prescription and OTC drug products from Tri-Med Labs

At the request of the U.S. Food and Drug Administration, U.S. Marshals seized articles of prescription and over-the-counter (OTC) drug products from Tri-Med Laboratories Inc. in Somerset, N.J. earlier this month. The seizure warrant, issued by the U.S. District Court for the District of New Jersey and unsealed this week, shows the drugs are unapproved and adulterated new drugs.

28 Oct 2010

AnaptysBio announces issuance of two new patents for SHM-XEL platform

AnaptysBio, Inc., a privately-held therapeutic antibody platform and product company, announced the issuance of patents in the US and Europe that provide additional coverage for its SHM-XEL platform. These patents extend AnaptysBio's leadership in the use of somatic hypermutation (SHM) for the discovery and optimization of antibodies and other proteins.

28 Oct 2010

The Methodist Hospital Research Institute opens 12-story, 440,000 square foot research facility

The Methodist Hospital Research Institute® (TMHRI) today opened a 12-story, 440,000 square foot research facility dedicated solely to research and equipped with the world's most advanced technology to help research scientists, physicians and engineers cure diseases that afflict today's patients.

28 Oct 2010

New global event focuses on childhood psoriasis

October 29 is World Psoriasis Day. Conceived by patients for patients, World Psoriasis Day is a truly global event focusing on the burden of living with psoriasis. There are more than 125 million people with psoriasis/psoriatic arthritis in the world. Many are children. Psoriasis is a severe chronic inflammatory disease that effects all ages, genders, races and ethnicities.

28 Oct 2010

Mylan's motion for interim injunction denied by Third Circuit Court of Appeals

Mylan Inc. today announced that the Third Circuit Court of Appeals denied its motion for an interim injunction pending an on-going appeal of a recent New Jersey District Court decision.

28 Oct 2010

JMC Professor wins Karl Storz Lifetime Achievement Award in Endourology

Demetrius H. Bagley, M.D., the Nathan Lewis Hatfield Professor of Urology in the Department of Urology at Jefferson Medical College (JMC) of Thomas Jefferson University was recently honored as the 2010 recipient of the Karl Storz Lifetime Achievement Award in Endourology at the World Congress of Endourology. He is also a full Professor of Radiology.

28 Oct 2010

High urine BPA levels associated with decreased sperm quality

Increasing urine BPA (Bisphenol-A) level was significantly associated with decreased sperm concentration, decreased total sperm count, decreased sperm vitality and decreased sperm motility, according to a Kaiser Permanente study appearing in the journal of Fertility and Sterility.

28 Oct 2010

Laureate enters agreement with AVEO to produce AV-203 monoclonal antibody against ErbB3

Laureate Pharma, Inc., a full-service contract development and manufacturing organization, announced today that they have entered into a development and manufacturing agreement to produce AV-203, AVEO Pharmaceutical's (Cambridge, MA) novel monoclonal antibody targeted against ErbB3.

28 Oct 2010

Even most vulnerable infants can transition to breast-feeding: Study

Pediatric researchers at The Children's Hospital of Philadelphia describe a successful program in which nurses helped mothers attain high rates of breast-feeding in very sick babies--newborns with complex birth defects requiring surgery and intensive care.

28 Oct 2010