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Increase in levels of P450 protein creates EET molecules that lower blood pressure

If you are one of the millions of Americans with high blood pressure, more help is on the way. That's because a new research study published in the October 2010 print issue of The FASEB Journal shows that a protein, called P450, metabolizes arachidonic acid in our blood vessel walls to create a tiny molecule with a big name-epoxyeicosatrienoic acid (EET)-which in mice, turns off genes responsible for vascular inflammation and ultimately relaxes blood vessels to lower blood pressure. This protein and genes are also present in humans.

1 Oct 2010

Intra-Cellular Therapies demonstrates ability of ITI-002 to improve motor and non-motor behaviors in PD

Intra-Cellular Therapies, Inc. today announced results from studies demonstrating the anti-Parkinson and other beneficial effects of ITI-002 (IC200214), the Company's novel and selective phosphodiesterase type I (PDE1) inhibitor.

1 Oct 2010

GSA urges treatment of sepsis as a medical emergency

The Global Sepsis Alliance (GSA) is urging healthcare providers, patients and policymakers worldwide to treat sepsis as a medical emergency. "Tens of millions of people die from sepsis each year, making it the likely leading cause of death worldwide. Sepsis kills regardless of age, ethnicity, location and access to care," said Konrad Reinhart, M.D., Chairman of the GSA and director of the Department of Anesthesiology and Intensive Care Medicine, University Hospital of the Friedrich Schiller, University of Jena, Germany.

1 Oct 2010

Healthy respect for flu this season

Flu season officially begins Friday, Oct. 1, and unlike last year's season when shortages lead to rationing, there will be plenty of vaccine on hand for everyone who wants a flu shot.

1 Oct 2010

FDA grants Emergent Fast Track Designation for AVP-21D9 anthrax monoclonal antibody development program

Emergent BioSolutions Inc. announced today that its anthrax monoclonal antibody development program investigating AVP-21D9 for the treatment of inhalational anthrax has been granted Fast Track Designation by the U.S. Food and Drug Administration (FDA). Emergent recently commenced a Phase I clinical trial for AVP-21D9, which is a fully human monoclonal antibody product candidate being developed as a parenteral post-exposure therapeutic to treat symptoms of inhalational anthrax disease.

1 Oct 2010

CDC awards ACS and GWCI $4.25 million to establish National Cancer Survivorship Resource Center

The American Cancer Society (ACS) and the GW Cancer Institute (GWCI) were recently awarded $4.25 million by the Centers for Disease Control (CDC) to establish a National Cancer Survivorship Resource Center. Work on the project will begin on September 30.

1 Oct 2010

Mylan subsidiary launches Bupropion Hydrochloride Extended-release Tablets

Mylan Inc. today announced that its subsidiary Mylan Pharmaceuticals Inc. has launched Bupropion Hydrochloride Extended-release Tablets USP, (XL), 150 mg and 300 mg (Once-Daily), the generic version of GlaxoSmithKline's antidepressant Wellbutrin XL®.

1 Oct 2010

iMedX acquires FORE Transcriptions USA

iMedX Inc., a leading healthcare software and services company, announced today that it has acquired FORE Transcriptions USA Inc., along with its Indian operations, FORE Transcriptions Pvt. Ltd. With this acquisition, iMedX adds FORE's many clinics and solo practitioners in Southwestern Texas to its customer base and significantly enhances its global transcription production capacity in one of India's prime technology hubs.

1 Oct 2010

New co-branded Medicare Part D prescription drug plan from Humana and Walmart

Today, Humana Inc. announced an innovative Medicare Part D prescription drug plan, co-branded with Wal-Mart Stores, Inc., that can provide significant savings on monthly plan premiums and prescription medicine copayments and cost-shares for Medicare beneficiaries, including seniors and people with disabilities.

1 Oct 2010

DaVita announces $1.45 billion Senior Notes offering

DaVita Inc. announced today that it intends to offer, subject to market and other conditions, $1.45 billion principal amount of senior notes (the "Senior Notes").

1 Oct 2010

First Edition: October 1, 2010

In this morning's headlines -- Medicaid enrollment spikes and the interplay between the federal government and McDonald's gets more attention.

1 Oct 2010

EXFO announces sale of Life Sciences and Industrial Division to The Riverside Company

EXFO Inc. announced today that it has sold its Life Sciences and Industrial Division to The Riverside Company, a global private equity firm, for US$24.3 million in cash. The purchase price is subject to adjustments for minimum working capital requirements.

1 Oct 2010

New method for detecting spores of non-proteolytic Clostridium botulinum

The Institute of Food Research has collaborated in the development of a new method for detecting spores of non-proteolytic Clostridium botulinum. This bacterium is the major health hazard associated with refrigerated convenience foods, and these developments give the food industry and regulators more quantitative information on which to base the procedures that ensure food safety.

1 Oct 2010

Study examines link between insufficient sleep and blood pressure among pregnant women

A study in the Oct. 1 issue of the journal Sleep found that getting too little or too much sleep in early pregnancy is associated with elevated blood pressure in the third trimester. The study suggests that improving prenatal sleep hygiene may provide important health benefits.

1 Oct 2010

FDA issues Complete Response Letter for Teva's Neutroval BLA

Teva Pharmaceutical Industries Ltd. announced today that the U.S. Food and Drug Administration (FDA) has issued a Complete Response Letter for the Biologic License Application (BLA) for Neutroval™ (granulocyte colony-stimulating factor) for the reduction in the duration of severe neutropenia and the incidence of febrile neutropenia in patients treated with established myelosuppressive chemotherapy for cancer.

1 Oct 2010

First nationwide Safe Medication Disposal Program launched

Walgreens has launched the first ongoing, nationwide Safe Medication Disposal Program, a safe and environmentally responsible way to dispose of unused or expired medications.

1 Oct 2010

Center for Excellence in Sickle Cell Disease established by Vanderbilt and Meharry

A Vanderbilt-Meharry Center for Excellence in Sickle Cell Disease has been established by Vanderbilt University Medical Center and Meharry Medical College. The Center will seek to bring high quality care to people with sickle cell disease (SCD) that is seamless and lifelong.

1 Oct 2010

Study suggests balance between NF-kB and p53 signaling as a promising target for new cancer drugs

A new report published in the October 2010 print issue of The FASEB Journal offers a ray of hope in the search for new cancer drugs. By examining the seemingly conflicting roles of how oncogenes and tumor suppressor genes handle cellular stress, scientists from the Institute for Advanced Studies in New Jersey argue that each of these opposing systems could be potent drug targets in the effort to stop cancer. In addition, their hypothesis provides new insights into what contributes to immunological disorders such as chronic inflammation and autoimmune diseases.

1 Oct 2010

UC San Diego researcher receives 'Era of Hope Scholar Award' for innovation in breast cancer study

Seth Field, MD, PhD, associate professor in the Department of Medicine at UC San Diego, has been awarded a five-year, $3.86 million "Era of Hope Scholar Award" from the Department of Defense Breast Cancer Research Program. The award supports individuals who have high potential for innovation in breast cancer research early in their careers, researchers considered the "best and brightest" in their field through "extraordinary creativity, vision and productivity and potential for leadership in the breast cancer research community.

1 Oct 2010

Lying creates desire to clean the 'dirty' body part: Study

Apparently your mom had it right when she threatened to wash your mouth out with soap if you talked dirty. Lying really does create a desire to clean the "dirty" body part, according to a University of Michigan study.

1 Oct 2010

Medical News

Increase in levels of P450 protein creates EET molecules that lower blood pressure

Intra-Cellular Therapies demonstrates ability of ITI-002 to improve motor and non-motor behaviors in PD

GSA urges treatment of sepsis as a medical emergency

Healthy respect for flu this season

FDA grants Emergent Fast Track Designation for AVP-21D9 anthrax monoclonal antibody development program

CDC awards ACS and GWCI $4.25 million to establish National Cancer Survivorship Resource Center

Mylan subsidiary launches Bupropion Hydrochloride Extended-release Tablets

iMedX acquires FORE Transcriptions USA

New co-branded Medicare Part D prescription drug plan from Humana and Walmart

DaVita announces $1.45 billion Senior Notes offering

First Edition: October 1, 2010

EXFO announces sale of Life Sciences and Industrial Division to The Riverside Company

New method for detecting spores of non-proteolytic Clostridium botulinum

Study examines link between insufficient sleep and blood pressure among pregnant women

FDA issues Complete Response Letter for Teva's Neutroval BLA

First nationwide Safe Medication Disposal Program launched

Center for Excellence in Sickle Cell Disease established by Vanderbilt and Meharry

Study suggests balance between NF-kB and p53 signaling as a promising target for new cancer drugs

UC San Diego researcher receives 'Era of Hope Scholar Award' for innovation in breast cancer study

Lying creates desire to clean the 'dirty' body part: Study

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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