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Angina drug nifedipine safe for long-term use

Calcium antagonists such as nifedipine are used to relieve the symptoms of angina, but there have been doubts about their long-term safety. However, ACTION--A Coronary disease Trial Investigating Outcome with Nifedipine GITS--provides new information on the drug's long-term use. GITS (gastrointestinal therapeutic system) modifies the release of the drug to provide stable long-term concentrations of nifedipine in blood.

30 Aug 2004

Researchers explain dual effects of ginseng

In work that emphasizes the need for stronger regulations of herbal drugs, an international team of MIT scientists and colleagues has unraveled the yin and the yang of ginseng, or why the popular alternative medicine can have two entirely different, opposing effects on the body.

30 Aug 2004

Patent issued for novel method to chill body tissues and organs without forming ice crystals

Body tissues such as blood vessels, cartilage and skin - even whole organs such as kidneys, livers and hearts - could become more widely available for transplants as a result of a patent issued recently to Organ Recovery Systems of Chicago for a method to chill body tissues and organs well below freezing without forming ice crystals.

30 Aug 2004

Flaw in DNA helps explain cancers and aging

Their finding explains how oxidative DNA damage - a process long believed to underlie cancers and aging - can create permanent genetic damage.

30 Aug 2004

Condition causing obstruction of arteries important in high blood pressure diagnosis and treatment

An under-recognized and usually asymptomatic condition called subclavian artery stenosis – an obstruction of arteries located under the clavicle, or collarbone – is important in the diagnosis and treatment of high blood pressure

30 Aug 2004

Kiwis reverse heart disease in diabetics

New Zealand biopharmaceutical company Protemix Corporation has announced the discovery of a treatment which appears to reverse heart disease in people suffering from diabetes and may lead to a more effective intervention in a major cause of death worldwide.

30 Aug 2004

Circadian rhythm research may lead to greater understanding of jet lag and human diseases

Our biological clock, or circadian rhythm, is upset by travelling across time zones, but very soon the body adjusts to the new day/night cycle.

30 Aug 2004

Surgery for angina in the elderly provides long-term mortality

Elderly people who undergo surgery or angioplasty to treat chest pain fare just as well long-term as those treated with medication, researchers report in Circulation: Journal of the American Heart Association.

30 Aug 2004

Gene - beta1-integrin, could be key to breast cancer therapies

Canadian researchers at the Research Institute of the McGill University Health Centre and McMaster University have identified a new player in breast cancer. This gene, beta1-integrin, has been shown to be critical in the initiation of tumour growth and development in a mouse model of cancer.

30 Aug 2004

African-Americans and Asians more pessimistic about the health systems ability to cope with a bioterrorist event

While nearly three-quarters of Americans believe that the public health system would respond fairly in a bioterrorist event, African-Americans and Asians adhere to this view in smaller proportions, perhaps because of past discriminatory policies put in place by health officials, according to a new UCLA study.

30 Aug 2004

Diabetes mellitus in acute coronary syndromes – worse for women

Diabetes is associated with worse prognosis in patients with myocardial infarction, but if there is a difference between men and women in this respect is less well known.

30 Aug 2004

Summary of The Euro Heart Survey on the diabetic state of patients with coronary artery disease

The survey engaged 110 centres in 25 countries recruiting 4,196 patients referred to a cardiology department or outpatient clinic due to CAD. A total of 2 107 of these patients were admitted on acute basis while 2,854 had an elective consultation. Patient data were collected via a web-based case record form.

30 Aug 2004

Common enzyme acts as a natural brake to prevent potentially deadly runaway inflammation

An enzyme found in nearly all animal and human cells acts as a natural brake to prevent potentially deadly runaway inflammation, UCSF scientists have discovered.

30 Aug 2004

Study suggests intramyocardial injection of cells from bone marrow might be an alternative for heart transplantation

Cardiovascular disease remains the leading cause of morbidity and mortality around the world and patients with end-stage ischemic heart failure carry the highest morbid-mortality rate.

30 Aug 2004

Converting cells into heart muscle

This plasticity concept – the ability of bone marrow cell to transdifferentiate into heart muscle cell – is supported by experimental and clinical data. Another possibility is to replace the missing function by causing transdifferentiation of existing cells. Transdifferentiation means converting one sort of cell, e.g. fibroblast, into another, e.g. muscle cell.

30 Aug 2004

Cinical trial to evaluate breakthrough breast cancer treatment

Virginia Commonwealth University’s Massey Cancer Center will host 20 medical experts from around the United States on Sept. 9 to prepare for a 3,000-patient phase III clinical trial that will evaluate a breakthrough breast cancer treatment.

30 Aug 2004

Early use of aggressive statin therapy may offer some benefit for coronary patients

Statins initiated early after a patient experiences an acute coronary syndrome (ACS) event at dosages above the typical starting dose may help reduce subsequent cardiovascular events, but the high dose regimen used may increase the risk for muscle-related complications, according to the results from the Phase Z portion of the A to Z Trial released on the JAMA website today.

30 Aug 2004

Medical News

Angina drug nifedipine safe for long-term use

Researchers explain dual effects of ginseng

Patent issued for novel method to chill body tissues and organs without forming ice crystals

Flaw in DNA helps explain cancers and aging

Condition causing obstruction of arteries important in high blood pressure diagnosis and treatment

Kiwis reverse heart disease in diabetics

Circadian rhythm research may lead to greater understanding of jet lag and human diseases

Surgery for angina in the elderly provides long-term mortality

Gene - beta1-integrin, could be key to breast cancer therapies

African-Americans and Asians more pessimistic about the health systems ability to cope with a bioterrorist event

Diabetes mellitus in acute coronary syndromes – worse for women

Summary of The Euro Heart Survey on the diabetic state of patients with coronary artery disease

Common enzyme acts as a natural brake to prevent potentially deadly runaway inflammation

Study suggests intramyocardial injection of cells from bone marrow might be an alternative for heart transplantation

Converting cells into heart muscle

Cinical trial to evaluate breakthrough breast cancer treatment

Early use of aggressive statin therapy may offer some benefit for coronary patients

Students are more likely to drink, smoke cigarettes and smoke marijuana when they receive drivers’ licenses

The Australian Government response to Senate inquiry into hepatitis C and blood supply

High blood pressure combined with elevated LDL cholesterol more than triples risk of heart attack

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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