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Novel fusion protein drug for Alzheimer’s disease circumvents the neurotoxic inflammatory side effects

Although Aduhelm, a monoclonal antibody targeting amyloid beta (Aβ), recently became the first US FDA approved drug for Alzheimer's disease (AD) based on its ability to decrease Aβ plaque burden in AD patients, its effect on cognitive improvement is still controversial.

4 Aug 2022

Exposure to air pollutants released during wildfires has ill effects among children

New research linking air pollution data from federal monitors in the Sacramento area of California, including during significant fires, is showing ill effects of pollution exposure among children, a new University of California, Davis, study suggests.

4 Aug 2022

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

Mitochondria are organelles found within most cells, best known for generating the chemical energy required to power cellular functions.

4 Aug 2022

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience.

4 Aug 2022

KHN’s ‘What the Health?’: Kansas makes a statement

Voters in Kansas told the rest of the country this week that they don't want their state to ban abortion. In a nearly 60%-40% split, voters turned back an effort by anti-abortion activists to amend the state constitution to remove its right to abortion, which would have allowed the legislature to ban the procedure.

4 Aug 2022

What is the severity of SARS-CoV-2 Omicron BA.4 and BA.5 variant infections in relation to BA.2 infections?

Researchers compared clinical outcomes of COVID-19 cases due to SARS-CoV-2 Omicron BA.2 and Omicron BA.4/BA.5 variants based on the Kaiser Permanente Southern California (KPSC) health records between April 29 and July 2, 2022.

4 Aug 2022

What is the viral rebound in untreated COVID-19 infections?

Researchers assessed the coronavirus disease 2019 (COVID-19) rebound in untreated COVID-19 infections.

4 Aug 2022

Polymer-embedded copper-based nanoparticles prevent surface contamination by viruses

In a new study, researchers developed nanocomposite coatings to prevent surface contamination by a human coronavirus (HCoV).

4 Aug 2022

Novel tool measures general and COVID‐19-specific sources of nurses' moral distress

The COVID‐19 pandemic created novel patient care circumstances that may have increased nurses' moral distress, including COVID‐19 transmission risk and end‐of‐life care without family present. Moral distress is a growing concern in healthcare with implications for both provider and patient outcomes.

4 Aug 2022

Johns Hopkins Medicine-led consortium awarded up to $200 million to address the global burden of tuberculosis

To address the global burden of tuberculosis (TB), one of humankind's oldest scourges, an international collaboration led by Johns Hopkins Medicine has today been awarded up to $200 million in research funding over five years by the U.S. Agency for International Development (USAID) Supporting, Mobilizing and Accelerating Research for Tuberculosis Elimination (SMART4TB) project.

4 Aug 2022

National MS Society commits $19 million to launch 40 multi-year research awards to drive progress towards new cures

The National Multiple Sclerosis Society has committed $19 million to launch 40 new multi-year research awards to drive progress toward stopping MS, restoring function, and ending MS forever – the goals of the widely endorsed Pathways to Cures for MS to better align the global MS research community around the most promising areas to cure MS for every single person as fast as possible.

4 Aug 2022

Study highlights the urgency of removing barriers to accessing medications for opioid use disorder

The opioid overdose and death epidemic continues to worsen across the United States, but medications such as methadone, buprenorphine, and extended-release naltrexone are proven to reduce opioid overdoses by more than 50 percent.

4 Aug 2022

HPV vaccine together with surgical treatment for cervical lesions may reduce recurrence of preinvasive disease

Giving women the human papillomavirus (HPV) vaccine around the time they have surgery for precancerous cervical lesions might lead to a reduction in the risk of lesions returning as well as other HPV-related diseases, suggests a study published by The BMJ today.

4 Aug 2022

CHOP helps launch new computational platform to harmonize pediatric cancer data

Children's Hospital of Philadelphia has helped launch a new computational platform that will harmonize pediatric cancer data, allowing researchers, pharmaceutical companies, and advocacy groups to accelerate the pace of drug development for pediatric cancer.

4 Aug 2022

Monoclonal antibody protects U.S. adults from malaria, Phase 1 clinical trial shows

One injection of a candidate monoclonal antibody (mAb) known as L9LS was found to be safe and highly protective in U.S. adults exposed to the malaria parasite, according to results from a National Institutes of Health Phase 1 clinical trial published in The New England Journal of Medicine.

4 Aug 2022

Incubation period, generation time, and reproduction number of initial monkeypox cases in Italy

In a new study, researchers analyzed the first human monkeypox cases in Italy.

4 Aug 2022

What is the impact of COVID-19 on children's media usage?

Researchers assessed the media usage by children during the coronavirus disease 2019 (COVID-19) pandemic.

4 Aug 2022

New easy-to-use test could rapidly diagnose heart attacks and cancers

Imperial researchers have built a new easy-to-use test that could diagnose non-infectious diseases like heart attacks and cancers more quickly.

4 Aug 2022

Higher suPAR levels linked with increased risk of blood clot formation

Blood clots are thought to occur in as many as a third of patients hospitalized with COVID-19. In many cases these clots can be deadly, such as pulmonary embolisms - blood clots that travel to the lungs. In fact, in nearly one third of patients with COVID-19, these clots led to death.

4 Aug 2022

Clinical and demographic inequalities in COVID-19-associated mortality

Researchers quantified the relative and absolute changes in COVID-19-related mortality based on clinical and demographical profiles of 18 million adult patients throughout the pandemic in England.

4 Aug 2022

Medical News

Novel fusion protein drug for Alzheimer’s disease circumvents the neurotoxic inflammatory side effects

Exposure to air pollutants released during wildfires has ill effects among children

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

KHN’s ‘What the Health?’: Kansas makes a statement

What is the severity of SARS-CoV-2 Omicron BA.4 and BA.5 variant infections in relation to BA.2 infections?

What is the viral rebound in untreated COVID-19 infections?

Polymer-embedded copper-based nanoparticles prevent surface contamination by viruses

Novel tool measures general and COVID‐19-specific sources of nurses' moral distress

Johns Hopkins Medicine-led consortium awarded up to $200 million to address the global burden of tuberculosis

National MS Society commits $19 million to launch 40 multi-year research awards to drive progress towards new cures

Study highlights the urgency of removing barriers to accessing medications for opioid use disorder

HPV vaccine together with surgical treatment for cervical lesions may reduce recurrence of preinvasive disease

CHOP helps launch new computational platform to harmonize pediatric cancer data

Monoclonal antibody protects U.S. adults from malaria, Phase 1 clinical trial shows

Incubation period, generation time, and reproduction number of initial monkeypox cases in Italy

What is the impact of COVID-19 on children's media usage?

New easy-to-use test could rapidly diagnose heart attacks and cancers

Higher suPAR levels linked with increased risk of blood clot formation

Clinical and demographic inequalities in COVID-19-associated mortality

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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