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CU Anschutz study details the mechanisms behind the link between shingles and strokes

Scientists investigating why people who have had shingles are at a higher risk of stroke, now believe the answer lies within lipid vesicles called exosomes that shuttle proteins and genetic information between cells, according to new research from the University of Colorado Anschutz Medical Campus.

28 Oct 2022

Large listeriosis outbreak in Spain caused by contaminated stuffed pork

Listeria bacteria are ubiquitous in the environment and consumption of food contaminated with Listeria monocytogenes is one of the main routes for food-borne outbreaks.

28 Oct 2022

The impact of seasonal coronavirus immunity on susceptibility to SARS-CoV-2 infection and COVID-19 vaccination

Researchers investigated whether immunity against seasonal human coronavirus spike proteins of HKU1, OC43, NL63, or 229E could protect against SARS-CoV-2 in vitro.

28 Oct 2022

Booster vaccination offered additional protection to residents and staff of California state prisons against SARS-CoV-2 Omicron

Researchers evaluated to what extent prior infection and vaccination protected the residents and staff of the United States California state prison system from breakthrough infection by SARS-CoV-2 Omicron sub-variant B.1.1.529.

28 Oct 2022

Study refutes the nicotinic hypothesis of SARS-CoV-2 infection mechanism

A new study confirmed that the SARS-CoV-2 spike protein does not bind to human AChR’s orthosteric sites, nor does it compete with ACh, choline, or nicotine.

28 Oct 2022

What are the contemporary hazards of cigarette smoking and benefits of quitting smoking by race, ethnicity, and sex among US adults?

Researchers quantified the association between cigarette smoking and all-cause and cause-specific deaths by sex, ethnicity, and race.

28 Oct 2022

E-cigarette use alters respiration but does not impair lung function, according to new findings

A new study indicated that although vaping increases airway resistance, it does not impact lung function.

28 Oct 2022

The epigenetic alterations of monocytes in severe COVID-19

Researchers performed DNA methylation analysis on monocytes in the peripheral blood samples obtained from severe COVID-19 patients.

28 Oct 2022

When monkeypox reaches rural communities, it collides with strained public health systems

When a case of monkeypox was reported in Nevada's Humboldt County in August, it was the state's first detected occurrence of the virus in a rural area. Soon, cases were found in other rural counties — Nye, Lyon, and Elko — posing another hurdle for public health systems that have been worn thin by the covid-19 pandemic.

28 Oct 2022

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

Researchers evaluated the concurrent colonization of fungi in the nasopharynx of severe COVID-19 patients.

28 Oct 2022

The dynamics of COVID-19 conspiracist ideation

Researchers studied the dynamics of COVID-19 conspiracist ideation—a general tendency to believe in conspiracy theories.

28 Oct 2022

Overall cancer death rates continue to decline in the United States, says Annual Report to the Nation

Overall cancer death rates continued to decline among men, women, children, and adolescents and young adults in every major racial and ethnic group in the United States from 2015 to 2019, according to the latest Annual Report to the Nation on the Status of Cancer. From 2014 to 2018, overall cancer incidence, or new cases of cancer, remained stable for men and children but increased for women and adolescents and young adults.

28 Oct 2022

AI models improve the accuracy of diagnosing coronary artery disease

Several recent discoveries show that the accuracy of diagnosing coronary artery disease and predicting patient risk is improved with the help of artificial intelligence (AI) models developed by scientists in the Division of Artificial Intelligence in Medicine at Cedars-Sinai.

28 Oct 2022

Research reveals a differential clinical response to pembrolizumab in uterine cancer patients

New research from Yale Cancer Center reveals for the first time ever a differential clinical response to pembrolizumab in Lynch-like (mutated) vs methylated microsatellite instability-high (MSI-H) uterine cancer patients, increasing our understanding about the proportion of patients that derive benefit from immune checkpoint blockade.

28 Oct 2022

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Genetic mutations kick start cancers. Some mutations shuffle the genetic code, others come from the deletion of key genes.

28 Oct 2022

ADOS testing not required for ASD diagnosis by developmental-behavioral pediatricians

Trained developmental-behavioral pediatricians can generally diagnose autism spectrum disorder (ASD) in young children without the need for additional Autism Diagnostic Observation Schedule (ADOS) testing, finds a prospective multicenter study.

28 Oct 2022

Low-density granulocytes are phenotypically altered in people with long-COVID

In a recent study posted to the bioRxiv* preprint server, researchers characterized low-density granulocyte (LDG) neutrophil (NP) proportion among individuals up to 14 months post-SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection.

28 Oct 2022

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

A team of researchers from the United States computationally modified the COV2-2130 monoclonal antibody to restore its neutralizing ability against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants, while retaining efficacy against the Delta and wild-type strains.

27 Oct 2022

Commensal gut microbes from IBD patients produce genotoxic metabolites

Functional screening of human gut microbiota reveals a family of small molecule genotoxins called indolimines in patients with inflammatory bowel disease (IBD), according to a new study.

27 Oct 2022

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, an international team of researchers leveraged the human light chain apoferritin protomer-derived MULTI-specific, multi-Affinity antibody (Multabody, MB) platform for the generation of broad and potent SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)-neutralizing antibodies (Abs).

27 Oct 2022

Medical News

CU Anschutz study details the mechanisms behind the link between shingles and strokes

Large listeriosis outbreak in Spain caused by contaminated stuffed pork

The impact of seasonal coronavirus immunity on susceptibility to SARS-CoV-2 infection and COVID-19 vaccination

Booster vaccination offered additional protection to residents and staff of California state prisons against SARS-CoV-2 Omicron

Study refutes the nicotinic hypothesis of SARS-CoV-2 infection mechanism

What are the contemporary hazards of cigarette smoking and benefits of quitting smoking by race, ethnicity, and sex among US adults?

E-cigarette use alters respiration but does not impair lung function, according to new findings

The epigenetic alterations of monocytes in severe COVID-19

When monkeypox reaches rural communities, it collides with strained public health systems

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

The dynamics of COVID-19 conspiracist ideation

Overall cancer death rates continue to decline in the United States, says Annual Report to the Nation

AI models improve the accuracy of diagnosing coronary artery disease

Research reveals a differential clinical response to pembrolizumab in uterine cancer patients

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

ADOS testing not required for ASD diagnosis by developmental-behavioral pediatricians

Low-density granulocytes are phenotypically altered in people with long-COVID

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

Commensal gut microbes from IBD patients produce genotoxic metabolites

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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