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New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

When the coronavirus causing COVID-19 infects human cells, the cell's protein-processing machinery makes modifications to the spike protein that render it more flexible and mobile, which could increase its ability to infect other cells and to evade antibodies, a new study from the University of Illinois Urbana-Champaign found.

6 Jul 2022

Research highlights importance of designing effective COVID vaccine allocation strategies

In a recent study posted to the medRxiv* pre-print server, researchers at the University of Melbourne used a modified Susceptible, Exposed, Infectious, and Recovered (SEIR) mathematical model to examine the impact of different vaccine mechanisms and disease characteristics on a population comprised of individuals at high and low risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

6 Jul 2022

Bone marrow transplants may be an effective treatment for ALS, research suggests

Along with the central nervous system, the immune system may play a fundamental role in Amyotrophic Lateral Sclerosis (ALS), suggesting that bone marrow transplants may be an effective novel treatment for the neurodegenerative disease.

6 Jul 2022

Implementing a variety of nonpharmaceutical COVID-19 interventions in Brazil

When the first cases of COVID-19 appeared in Brazil in late February 2020, the twenty-seven Brazilian states responded by implementing a variety of nonpharmaceutical interventions: restrictions on public events, schools, and nonessential commerce, and somewhat later, masking ordinances.

6 Jul 2022

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

In a recent study published in the bioRxiv* preprint server, researchers at the Medical University of Innsbruck assessed the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CLpro mutations responsible for Paxlovid resistance. The 3-chymotrypsin-like protease (3CLPro), or main protease (Mpro), is the main protease found in coronaviruses.

6 Jul 2022

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

In a recent study posted to the medRxiv* pre-print server, researchers developed a mechanistic mathematical model to predict the course of vaccine-induced immunity in healthy and immunosuppressed patients for the long term, exceeding the time frames for which clinical data is currently available.

5 Jul 2022

What role does human microbiota play in COVID-19 severity?

In a recent study published in the journal Advanced Science, researchers explored the dynamic changes in the respiratory tract and gut microbiota in coronavirus disease 2019 (COVID-19) patients. They observed and analyzed these changes during different disease progression stages among patients with differential disease severities.

5 Jul 2022

Novel inhalable COVID-19 vaccine

A recent study published in the Nature Biomedical Engineering journal illustrated a novel inhalable SARS-CoV-2 vaccine candidate centered on exosomes (Exos) coupled with recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD).

5 Jul 2022

Scientists uncover HIV’s sweet spot

HIV researchers have long been trying to identify the specific cells that the virus prefers to infect and hide in. They know that HIV favors a special type of immune cells called memory CD4 T cells.

5 Jul 2022

Culturally-sensitive interventions could be effective in preventing alcohol-related problems in Latino students

Negative consequences from excessive drinking are well-documented, but little is known about how to tailor interventions to prevent problem drinking by Latino college students, the fastest-growing ethnic minority group on U.S. college campuses.

5 Jul 2022

Latest omicron subvariants are better at eluding vaccines and antibody treatments

The latest omicron subvariants - including the BA.4 and BA.5 forms causing new surges in infections in the United States - are even better at eluding vaccines and most antibody treatments than previous variants, finds a study by researchers at Columbia University Vagelos College of Physicians and Surgeons.

5 Jul 2022

Tobacco-cessation program must be expanded and extended to curb smoking among prisoners

More than half of all people incarcerated in the U.S. smoke cigarettes, a hidden health crisis that has long been under-researched and under-resourced.

5 Jul 2022

'Phantom' networks undermine access to mental health care for patients most in need, study says

Amid a surge in demand for mental health care, a new report from researchers at Oregon Health & Science University finds almost six out of 10 in-network providers listed under Oregon Medicaid provider directories are not actually available to see patients.

5 Jul 2022

What causes insomnia and how to treat it?

A new study evaluates the symptoms of insomnia and its treatment as reported by patients in primary care settings.

5 Jul 2022

Has the COVID pandemic affected breastfeeding intention?

A new study discusses the impact of the pandemic on breastfeeding practices.

5 Jul 2022

How is the microbiome of an infant influenced by mother's bacteria?

A recent study explores the sources and functional importance of certain key species in the mother-infant transmission of the microbiota.

5 Jul 2022

New policy brief evaluates Washtenaw County’s American Rescue Plan Act allocations

A new policy brief from the University of Michigan’s Poverty Solutions initiative offers recommendations for ways to target funding to key programs and priorities, focus on program implementation, and consider long-term impacts as Washtenaw County leaders decide how to allocate the rest of its American Rescue Plan Act money.

5 Jul 2022

Trial: Convalescent plasma does not improve survival or recovery in hospitalized COVID-19 patients

Convalescent plasma, widely given to severely ill patients hospitalized with COVID-19 during the pandemic, does not improve their ability to survive or recover, according to a national clinical trial led by Vanderbilt University Medical Center and published in the journal CHEST.

5 Jul 2022

Intensive nurse home visiting program did not improve birth outcomes for low-income mothers, finds study

A paper in the Journal of the American Medical Association found that Nurse-Family Partnership (NFP), a prenatal and early child home visiting program, did not improve birth outcomes for low-income mothers in South Carolina.

5 Jul 2022

Scientists unravel the neuronal metabolism in learning and memory

Exploring the predictive properties of neuronal metabolism can contribute to our understanding of how humans learn and remember.

5 Jul 2022

Medical News

New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

Research highlights importance of designing effective COVID vaccine allocation strategies

Bone marrow transplants may be an effective treatment for ALS, research suggests

Implementing a variety of nonpharmaceutical COVID-19 interventions in Brazil

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

What role does human microbiota play in COVID-19 severity?

Novel inhalable COVID-19 vaccine

Scientists uncover HIV’s sweet spot

Culturally-sensitive interventions could be effective in preventing alcohol-related problems in Latino students

Latest omicron subvariants are better at eluding vaccines and antibody treatments

Tobacco-cessation program must be expanded and extended to curb smoking among prisoners

'Phantom' networks undermine access to mental health care for patients most in need, study says

What causes insomnia and how to treat it?

Has the COVID pandemic affected breastfeeding intention?

How is the microbiome of an infant influenced by mother's bacteria?

New policy brief evaluates Washtenaw County’s American Rescue Plan Act allocations

Trial: Convalescent plasma does not improve survival or recovery in hospitalized COVID-19 patients

Intensive nurse home visiting program did not improve birth outcomes for low-income mothers, finds study

Scientists unravel the neuronal metabolism in learning and memory

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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