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Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Young people who received doses of tisagenlecleucel, a chimeric antigen receptor T cell (CAR-T) therapy, at the higher end of the FDA-approved dosing range had significantly better survival rates at one year compared with those who received lower doses within this range, according to research published today in Blood Advances.

8 Aug 2022

Inflation problem in the U.S. impacts Black families more than many other Americans

A new NPR/Robert Wood Johnson Foundation/Harvard T.H. Chan School of Public Health poll shows that at a time when households across the U.S. widely report experiencing serious problems from inflation, Black Americans are substantially more likely than whites to report they are currently having serious financial problems in this period (55% to 38%).

8 Aug 2022

Yale researchers discover molecular mechanism behind growth of the nervous system

Our nervous system is composed of billions of neurons that speak to each other through their axons and dendrites.

8 Aug 2022

Study explores the relationship between empathy and cyberbullying among early U.S. adolescents

Bullying has been made easier and sometimes more serious by social media, gaming platforms, and other online communications technologies, affecting so many of our schools, families and communities.

8 Aug 2022

COVID-19 vaccination increases antibodies in breast milk significantly

Anti-SARS-CoV-2 antibodies in breast milk capable of neutralizing both an early pandemic SARS-CoV-2 isolate and Omicron variant.

8 Aug 2022

Sperm not affected nine months after COVID-19 mRNA vaccination

A recent study compared the effects of COVID-19 vaccines on male fertility at a median of nine months after receipt of two mRNA vaccine doses.

8 Aug 2022

CDC identifies bacteria that cause rare melioidosis in domestic environmental samples

The Centers for Disease Control and Prevention (CDC) has identified for the first time in domestic environmental samples the bacteria that causes a rare and serious disease called melioidosis.

8 Aug 2022

First Phase II study of immunotherapy combined with curative radiotherapy for unresectable locally advanced NSCLC

Researchers from Japan today reported that the first phase II study to evaluate the efficacy and safety of durvalumab and concurrent curative radiation therapy for PD-L1-positive unresectable locally advanced non-small cell lung cancer without chemotherapy met its primary endpoint with tolerable adverse reactions.

8 Aug 2022

Consolidation PD-(L)1 inhibition following concurrent chemoradiation for unresectable stage III NSCLC improves survival

Following concurrent chemoradiation for unresectable stage III non-small cell lung cancer, both nivolumab alone and nivolumab and ipilimumab combined demonstrated improved 18- month progression-free survival compared with historical controls despite a shortened interval (6 months) of treatment.

8 Aug 2022

Lung cancer patients in a screening program who participated in stop smoking study achieve more than 30% abstinence rates

Patients with lung cancer who attended a lung cancer screening event and who then participated in a personalized smoking cessation study achieved smoking abstinence rates of more than 30 percent, according to research presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Neoadjuvant chemoimmunotherapy highly effective in patients with resectable stage IIIA NSCLC

In the initial NADIM trial, neoadjuvant chemoimmunotherapy was shown to be highly effective in patients with resectable stage IIIA non-small cell lung cancer.

8 Aug 2022

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Researchers from Spain have identified an immune expression signature in surgical specimens associated with disease progression for non-complete pathological responders patients treated with neo adjuvant chemo-immunotherapy, which could help the follow-up and therapeutic management of these high-risk patients.

8 Aug 2022

Trial evaluates sugemalimab as a consolidation treatment in patients with unresectable stage III NSCLC

The human monoclonal antibody sugemalimab is a safe and effective consolidation therapy for patients with unresectable stage III non-small cell lung cancer without disease progression after either concurrent chemoradiotherapy (cCRT) or sequential chemoradiotherapy (sCRT), according to findings presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

A study presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna disclosed the clinical-relevant intertumoral heterogeneity of non-small cell lung cancer (NSCLC) driven by MET exon 14 skipping.

8 Aug 2022

Study compares the nodule management protocols used in NELSON and National Lung Cancer Screening Trial

The protocol used to screen and detect lung cancer in the NELSON Trial is more sensitive than the protocol used in the National Lung Cancer Screening Trial, particularly for early-stage cancers, according to research reported today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Research highlights the need to increase early detection of lung cancer among younger patients

Younger patients with lung cancer are significantly more likely than older patients to be diagnosed with later stages of disease, illustrating the need to develop strategies to increase the early detection of lung cancer among younger patients who are currently ineligible for lung cancer screening.

8 Aug 2022

Sub lobar surgery found to be non-inferior to lobectomy for patients with small-sized peripheral NSCLC

A large international study of patients with non-small cell lung cancer tumors that are two centimeters or less found that sub lobar surgery was non-inferior to lobectomy, according to results presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Increased use of stereotactic body radiation therapy for NSCLC patients can reduce treatment disparities

The use of Stereotactic Body Radiotherapy (SBRT) for patients with non-small cell lung cancer can reduce treatment disparities between White and Black patients, according to research presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Researchers examine the incidence of second primary lung cancers using National Lung Screening Trial data

Using data from the National Lung Screening Trial, researchers found that the incidence of second primary lung cancer was approximately 4% among the entire cohort of lung cancer patients and was as high as 8% among patients undergoing surgery for stage IA disease.

8 Aug 2022

Researchers unravel the mechanism of teixobactin at the atomic level

Researchers explored the mechanisms underlying the bactericidal action of teixobactin at an atomic level.

8 Aug 2022

Medical News

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Inflation problem in the U.S. impacts Black families more than many other Americans

Yale researchers discover molecular mechanism behind growth of the nervous system

Study explores the relationship between empathy and cyberbullying among early U.S. adolescents

COVID-19 vaccination increases antibodies in breast milk significantly

Sperm not affected nine months after COVID-19 mRNA vaccination

CDC identifies bacteria that cause rare melioidosis in domestic environmental samples

First Phase II study of immunotherapy combined with curative radiotherapy for unresectable locally advanced NSCLC

Consolidation PD-(L)1 inhibition following concurrent chemoradiation for unresectable stage III NSCLC improves survival

Lung cancer patients in a screening program who participated in stop smoking study achieve more than 30% abstinence rates

Neoadjuvant chemoimmunotherapy highly effective in patients with resectable stage IIIA NSCLC

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Trial evaluates sugemalimab as a consolidation treatment in patients with unresectable stage III NSCLC

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

Study compares the nodule management protocols used in NELSON and National Lung Cancer Screening Trial

Research highlights the need to increase early detection of lung cancer among younger patients

Sub lobar surgery found to be non-inferior to lobectomy for patients with small-sized peripheral NSCLC

Increased use of stereotactic body radiation therapy for NSCLC patients can reduce treatment disparities

Researchers examine the incidence of second primary lung cancers using National Lung Screening Trial data

Researchers unravel the mechanism of teixobactin at the atomic level

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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