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Tribe embraces recreational marijuana sales on reservation where alcohol is banned

In a growing number of U.S. states, people can both drink alcohol and legally smoke recreational marijuana. In others, they can use alcohol but not pot. But on the Pine Ridge Indian Reservation in South Dakota, the opposite is true: Marijuana is legal, but booze is banned.

8 Aug 2022

Assessing immunization capacity of vaccine platforms with DNA origami harboring SARS-CoV-2 receptor binding domain

Researchers demonstrated that vaccine frameworks containing deoxyribonucleic acid (DNA) origami possessing SARS-CoV-2 receptor-binding domain induce strong protective immunity.

8 Aug 2022

Patients and doctors trapped in a gray zone when abortion laws and emergency care mandate conflict

Each week, Dr. Kim Puterbaugh sees several pregnant patients at a Cleveland hospital who are experiencing complications involving bleeding or infection.

8 Aug 2022

Researchers create a physical wiring diagram of the human immune system

In a new study, researchers systematically mapped the surface proteins on human leukocytes to examine interactions between their cell-surface proteomes and develop a physical wiring diagram encapsulating the diversity of surface protein architectures found across all major subsets of leukocytes.

8 Aug 2022

How can we map the human genetic architecture of COVID-19 across all ancestry groups?

In a new study, researchers formed the COVID-19 host genetics initiative to compile a genome-wide association meta-analysis of 60 studies from 25 countries.

8 Aug 2022

Boosting vitamin D in individuals with deficiencies likely to reduce chronic inflammation

Inflammation is an essential part of the body's healing process. But when it persists, it can contribute to a wide range of complex diseases including type 2 diabetes, heart disease, and autoimmune diseases.

8 Aug 2022

Implantable mechanotherapeutic drug delivery platform helps overcome host immune response

Implantable devices that release insulin into the body hold promise as an alternative way to treat diabetes without insulin injections or cannula insertions. However, one obstacle that has prevented their use so far is that the immune system attacks them after implantation, forming a thick layer of scar tissue that blocks insulin release.

8 Aug 2022

Modern humans did not experience an evolutionary decrease in brain size, UNLV research says

Did the 12th century B.C.E. - a time when humans were forging great empires and developing new forms of written text - coincide with an evolutionary reduction in brain size? Think again, says a UNLV-led team of researchers who refute a hypothesis that's growing increasingly popular among the science community.

8 Aug 2022

Terminally exhausted T cells may remain competent for transcription, researchers say

During a battle with cancer, T cells can become exhausted and are no longer able to function properly. The early phase of exhaustion can sometimes be reversed with immunotherapy drugs, but once T cells become too exhausted, it had been thought that this state was irreversible. However, new insights from University of Pittsburgh and UPMC researchers suggest that even the most fatigued T cells can be revived.

8 Aug 2022

BCG vaccine produces a "trained immunity response" which lasts more than a year

The immune boosting benefits of a tuberculosis vaccine can be seen in infants more than one year after vaccination, according to a new study.

8 Aug 2022

Researcher creates a portable, wearable device for rapid gas analysis

A University of Texas at Arlington electrical engineering researcher is creating a portable, wearable device for rapid gas analysis that could detect illness immediately.

8 Aug 2022

Wrist-wearable devices more cost-effective than electrocardiograms and pulse palpation for atrial fibrillation screening

Screening individuals for atrial fibrillation (AF) using wearable devices is more cost-effective than screening using conventional methods such as 12-lead electrocardiogram (ECG) and pulse palpation, or than no screening at all, researchers from Massachusetts General Hospital (MGH) have found.

8 Aug 2022

Varenicline and cytisine not more efficacious than nicotine to treat risky drinking and smoking, study says

A clinical trial to test whether three proven smoking cessation treatments could also reduce alcohol intake found no differences between the medications, but the rates of behavior change for alcohol consumption and smoking were high in all treatment groups. Results suggest these medications could play an important role to reduce alcohol use and smoking at the same time. Unexpectedly, nicotine replacement therapy performed as well as the prescription drugs varenicline and cytisine.

8 Aug 2022

Nivolumab approved for combination with fluoropyrimidine- and platinum-based combination chemotherapy

Nivolumab has recently been approved both in combination with fluoropyrimidine- and platinum-based combination chemotherapy and in combination with ipilimumab for the first-line treatment of adults with unresectable advanced, recurrent or metastatic esophageal squamous cell carcinoma with PD-L1 expression of at least one percent. The German Institute for Quality and Efficiency in Health Care (IQWiG) now examined in two early benefit assessments whether these two combinations have an added benefit for patients in comparison with chemotherapy alone.

8 Aug 2022

Optically controlled local heat-pulse method manipulates temperature in cells

A team of researchers led by Osaka University finds that mutant variants of the calcium channel protein RyR1 are hypersensitive to heat, which creates a positive feedback loop of calcium release and leads to malignant hyperthermia

8 Aug 2022

How do female sex hormones affect sleep, and memory?

Scientists describe the relationship between biological sex, memory, sleep, and hormones in relation to the risk of Alzheimer's disease and related dimentias.

7 Aug 2022

Study finds COVID associated with abnormal placental pathologies in nearly 50% of cohort

Researchers describe the impact of placental morphological changes in COVID-19 on pregnancy outcomes.

7 Aug 2022

French study on cardiovascular disease incidence during COVID pandemic and vaccination campaign

Researchers describe failures of the French healthcare system as reflected by increased hospitalizations due to certain acute cardiovascular diseases in 2021.

7 Aug 2022

New recommendations on how to determine eligibility criteria for lung cancer clinical trials

A clinical trial is only as powerful as its participants. For years, researchers have struggled to fill clinical trials and enroll sufficiently diverse groups of patients for results to reflect the broader population, in part because of stringent guidelines on who can participate.

5 Aug 2022

UC San Diego and Rady Children’s Hospital join new study to better understand long-term impact of COVID-19

Researchers at University of California San Diego School of Medicine and Rady Children's Hospital-San Diego have joined a nationwide study to better understand the long-term impact of COVID-19 on patients in the United States across all demographic groups.

5 Aug 2022

Medical News

Tribe embraces recreational marijuana sales on reservation where alcohol is banned

Assessing immunization capacity of vaccine platforms with DNA origami harboring SARS-CoV-2 receptor binding domain

Patients and doctors trapped in a gray zone when abortion laws and emergency care mandate conflict

Researchers create a physical wiring diagram of the human immune system

How can we map the human genetic architecture of COVID-19 across all ancestry groups?

Boosting vitamin D in individuals with deficiencies likely to reduce chronic inflammation

Implantable mechanotherapeutic drug delivery platform helps overcome host immune response

Modern humans did not experience an evolutionary decrease in brain size, UNLV research says

Terminally exhausted T cells may remain competent for transcription, researchers say

BCG vaccine produces a "trained immunity response" which lasts more than a year

Researcher creates a portable, wearable device for rapid gas analysis

Wrist-wearable devices more cost-effective than electrocardiograms and pulse palpation for atrial fibrillation screening

Varenicline and cytisine not more efficacious than nicotine to treat risky drinking and smoking, study says

Nivolumab approved for combination with fluoropyrimidine- and platinum-based combination chemotherapy

Optically controlled local heat-pulse method manipulates temperature in cells

How do female sex hormones affect sleep, and memory?

Study finds COVID associated with abnormal placental pathologies in nearly 50% of cohort

French study on cardiovascular disease incidence during COVID pandemic and vaccination campaign

New recommendations on how to determine eligibility criteria for lung cancer clinical trials

UC San Diego and Rady Children’s Hospital join new study to better understand long-term impact of COVID-19

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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