News Medical's "Thought Leaders" series is a selection of articles written by national and
international experts and trusted advisers in health and medicine. All the articles are
written by experts who have been invited as recognised leaders in their fields to provide
a "state of the art" contribution.
Rhomboid enzymes live in the cell’s membrane where their job is to cut the anchors of proteins, which releases the target proteins from the membrane.
Malignant mesothelioma is a rare tumor of the pleura which is the lining of the inside of the chest wall. It is highly linked with asbestos exposure.
Early stage breast cancer in older women is a common problem. In the United States nearly half of women diagnosed with breast cancer are aged 65 or older. A sizeable proportion of those patients have early stage breast cancer.
In Australia, people will only be offered a choice when the brands are bioequivalent, meaning they contain the same active ingredient (i.e. the chemical in the medicine that makes it work) and have been proven to work the same in the body.
What most of us think of as heartburn is a symptom of Reflux Disease or GERD (Gastroesophageal Reflux Disease). It’s that burning discomfort an individual experiences when stomach acids and other fluids come back up into their esophagus.
Schizophrenia is the most disabling disease impacting youth today. It impacts 1% of the total population and typically causes withdrawal from society, loss in IQ, disordered thought and speech, hallucinations and delusions.
It is important to say that levels of maternal obesity in sub-Saharan Africa are low by global standards, but obesity is projected to increase over the next two decades.
Medical ethics assists healthcare professionals to make decisions respectful of persons who happen to be their patients.
Anaemia is a condition in which the number of red blood cells in the body is lower than normal or these have lower amounts of haemoglobin, a protein that is involved in the oxygen exchange of the body.
Most donors die in intensive care units, frequently after car accidents. Once it is clear that recovery is out of the question, families will be told that further treatment is futile and the issue of donation can be sensitively raised.
The anti-HIV drugs, also known as anti-retroviral therapy, came about in the mid ‘90’s. These involved using at least 3 different drugs together.
Adverse drug effects are harms caused by the use of a medication. There are many different types of ADEs, including medication errors.
Breast cancer is the most important cancer for women in the developed world. About 20% of all patients diagnosed with breast cancer die of metastatic disease.
'What defines obesity in children' is a very important question, primarily because we need to use one definition in order to be able to compare the prevalence of obesity in different countries. It is also important to have a single definition in order to evaluate whether interventions are successful or not.
Parkinson’s disease is a disorder which usually affects people in their 60’s and older. It is caused by the loss of dopamine neurons in the brain leading to rigidity, slowness of movement, tremor, problems with balance and so forth.
The antioxidants that we mainly looked at were selenium, vitamin C and vitamin E. They are chemicals which inactivate pro-oxidants or free radicals. Smoking and normal metabolism can lead to the production of free radicals.
With the approach of the Olympic Games, a group of researchers throughout the world thought that it would be a good time to draw the attention of the world to the health dangers of being physically inactive.
TB is a leading global killer. It is the second leading infectious disease in the world, behind HIV. TB is spread through the air, so it can affect anyone, but has its worst impact on impoverished communities and those people with HIV.
Sexual intercourse is the major mode of HIV transmission. HIV may also be transmitted through sharing of needles or contaminated blood products (although this is rare).
Since its discovery in 1989, hepatitis C virus (HCV) has been recognized as a major cause of chronic liver disease worldwide. The most recent WHO estimate of the prevalence of HCV infection is 2%, representing . about 150 million people. Every year, 3–4 million new people are infected with the hepatitis C virus, of those, approximately 60–80% develop chronic hepatitis, and 30% of them progress to cirrhosis and to end-stage liver disease.