Sarcoidosis is a systemic, granulomatous disease with a range of organ involvement, most commonly the lungs. However, there are several challenges associated with sarcoidosis treatment, particularly in terms of diagnostics and monitoring.
This webinar from IBL International GmbH explores the use of serum IL-2 receptor (sIL-2R) testing in routine sarcoidosis care, featuring real-world examples from Antonius Hospital.
Antonius Hospital is a national referral center with a large patient volume. The hospital has adopted an interdisciplinary, networked approach to interstitial lung diseases, leveraging sIL-2R in its daily clinical practice for diagnosis, monitoring, and treatment decisions.
sIL-2R is also combined with other markers to enhance diagnostic confidence, for example, ACE and histotriatidase.
The interpretation of sIL-2R is discussed in the webinar, including its sensitivity and specificity. sIL-2R’s limitations are also explored, for instance, the impact of sIL-2R on renal function and its elevation in other diseases.
This discussion highlights the importance of a clear definition of biomarker use, with the real patient example showing how sIL-2R levels can help guide diagnosis, treatment, and early relapse detection.
sIL-2R’s correlation changes in line with lung function and treatment response. This key characteristic is discussed alongside its role in early relapse detection and enabling steroid-sparing strategies.
The value and limitations of PET scans as imaging biomarkers are also compared with sIL-2R, highlighting the need for more research and further development of appropriate guidelines.
One of the key benefits of this webinar includes learning about the integration of sIL-2R testing into routine sarcoidosis care at the pioneering Antonius Hospital, illustrated by practical, real-world examples of sIL-2R’s use in supporting diagnosis, monitoring, and treatment decisions.
Viewers will receive useful insights into combining sIL-2R with other markers, as well as using it in conjunction with imaging to achieve a more comprehensive clinical picture.
Finally, the detailed patient case demonstrates the value of sIL-2R in personalized care and early relapse detection, and provides practical guidance for implementing sIL-2R testing in a laboratory or clinical workflow.