Angioplasty News and Research

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In angioplasty procedures, a balloon is fed through a catheter and used to prop open an artery that has become narrowed or blocked. In cases where stenting is appropriate, a stent mounted on a balloon is inserted and inflation of the balloon expands the stent against the blocked artery wall to hold the vessel open. The balloon is then deflated and the catheter is withdrawn. Stent treatment of arteries holds them open and improves blood flow to the heart. In cases where post-dilatation is needed, a high-pressure balloon is inflated inside a stent to help better place the stent against the vessel wall.

Study confirms under-utilization of medication in patients after bypass surgery

Researchers at Thomas Jefferson University discovered that nearly half of coronary artery bypass patients are not taking statins and aspirin together when they are referred for diagnostic cardiac catheterization at least three years after their initial bypass. Their results are currently in press online in the American Journal of Cardiology.

3 May 2016

Investigational drug provides no improved protection to patients with contrast-induced acute kidney injury

Patients treated with CMX-2043--an investigational drug that has previously shown some ability to protect heart muscle from damage during stenting--saw no improved protection in their kidneys compared to placebo, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

5 Apr 2016

Ischemic postconditioning for STEMI patients shows no clinical outcomes

A large randomized controlled trial of ischemic postconditioning in patients who had experienced the deadliest form of heart attack—ST-segment elevation myocardial infarction (STEMI)—failed to show that this procedure significantly reduces death from any cause or hospitalization for heart failure, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Intravenous beta blockers offer no clinical benefit to patients with STEMI

Giving intravenous beta blockers before performing a coronary angioplasty in patients who had experienced the deadliest form of heart attack—ST-segment elevation myocardial infarction (STEMI)—was safe but did not reduce heart attack severity or improve blood flow from the heart's main pumping chamber, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Deferred stent implantation fails to show benefit in STEMI patients

Delayed or deferred stent implantation in patients experiencing the deadliest form of heart attack--ST-segment elevation myocardial infarction (STEMI)—failed to reduce death from any cause, hospitalization for heart failure, subsequent heart attacks or the need for a repeat procedure to restore blood flow to the heart, researchers reported at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Cutting-edge vascular implant technology available at PinnacleHealth for patients with claudication

PinnacleHealth CardioVascular Institute enrolled the first patient in Pennsylvania into the TOBA II clinical on October 19, 2015. This trial is to assess the safety and efficacy of a vascular implant for the treatment of dissections (tearing in the artery wall) that occur following balloon angioplasty (PTA) of the main artery in the leg.

22 Mar 2016

Acute mesenteric ischemia can be treated with balloon angioplasty

Acute mesenteric ischemia (AMI) can be successfully treated with endovascular therapy such as balloon angioplasty, according to research from the University of Eastern Finland. The study also found that AMI is a more common cause of abdominal pain among the elderly than generally thought; however, it is difficult to diagnose before bowel damage develops.

26 Feb 2016

Stenting and surgery equally effective at lowering long-term risk of stroke

Investigators for the Carotid Revascularization Endarterectomy versus Stenting Trial found that stenting and surgery are equally effective at lowering the long-term risk of stroke from a narrowed carotid artery, according to a study published today in The New England Journal of Medicine.

22 Feb 2016

ACC, AHA support implementation of proposed cardiovascular measures, with reservations

Quality measures announced today by the Core Quality Measures Collaborative represent a step forward in reducing paperwork and confusion while also allowing providers to focus on measures that impact patient outcomes, the American College of Cardiology (ACC) and the American Heart Association (AHA) said in support of implementation of the proposed cardiovascular measures. But the groups expressed reservations about blood pressure targets included in the measures.

17 Feb 2016

Heart attack patients experiencing cardiogenic shock at higher risk of death in first 60 days post-discharge

Heart attack patients who experience cardiogenic shock have a higher risk of death or rehospitalization than non-shock patients in the first 60 days post-discharge, but by the end of the first year, the gap between the two groups narrows, according to a study published today in the Journal of the American College of Cardiology.

16 Feb 2016

New methodology could spare kids from unnecessary heart surgery

What better way to celebrate Valentine's Day than help save a child's heart? That's what Vittoria Flamini, an industry assistant professor in Tandon's Department of Mechanical and Aerospace Engineering, has in mind.

15 Feb 2016

Ultrasound-activated microbubbles help preserve healthy heart tissue

Researchers funded by the National Institute of Biomedical Imaging and Bioengineering used ultrasound-activated microbubbles to improve preservation of heart muscle and function in a pig heart attack model.

12 Feb 2016

QT Vascular reports initial results from first-in-human study of Chocolate Heart drug-coated balloon

QT Vascular Ltd., together with its subsidiaries (the "Company" or "QT Vascular", and together with its subsidiaries, the "Group"), a global company engaged in the design, assembly and distribution of advanced therapeutic solutions for the minimally invasive treatment of vascular disease, announce today the release of the initial results from the first-in-human study of its unique drug-coated balloon, Chocolate Heart.

7 Jan 2016

Heart attack patients with bypass history more likely to have delayed treatment

Heart attack patients who had previously undergone cardiac bypass surgery are about twice as likely to have a delay in receiving angioplasty, or another form of revascularization, compared to heart attack patients who had no history of bypass surgery or previous angioplasty.

31 Dec 2015

Restoring blood flow quickly after heart attack symptoms appear may help reduce heart damage

While hospitals have made strides in reducing the time it takes to treat heart attack patients once they arrive at the hospital, patient delays recognizing symptoms and seeking treatment are associated with increased damage to the heart, according to a study published online today in JACC: Cardiovascular Interventions.

29 Dec 2015

New MRI-based technology could help identify patients at risk of recurrent stroke

Patients who have had a stroke in the back of the brain are at greater risk of having another within two years if blood flow to the region is diminished, according to results of a multicenter study led by researchers at the University of Illinois at Chicago.

22 Dec 2015

Treatment with antiplatelet therapy does not reduce pain crises in children with sickle cell disease

Treatment with the antiplatelet agent prasugrel does not significantly reduce the rate of pain crises or severe lung complications in children with sickle cell disease, according to a report published in the New England Journal of Medicine describing one of the largest and most geographically diverse international clinical trials on sickle cell disease to date.

9 Dec 2015

‘More is better’ for medical management of acute stroke

The outcomes of stroke patients assigned to receive medical therapy in the SAMMPRIS trial were significantly influenced by the experience of the centre in which they were treated, research shows.

20 Nov 2015

New treatment may help patients with chronic renovascular disease

A new treatment may help patients with a chronic kidney condition that can also lead to heart problems and premature death, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

6 Nov 2015

North Shore-LIJ researcher compares safety benefits two blood-thinning medications

A large, ambitious contrast of blood-thinning medications used during cardiac stent placement suggests that a very expensive drug offers no clear safety benefits over a much more affordable option, according to a prominent North Shore-LIJ researcher and cardiologist.

1 Sep 2015

Angioplasty News and Research

Study confirms under-utilization of medication in patients after bypass surgery

Investigational drug provides no improved protection to patients with contrast-induced acute kidney injury

Ischemic postconditioning for STEMI patients shows no clinical outcomes

Intravenous beta blockers offer no clinical benefit to patients with STEMI

Deferred stent implantation fails to show benefit in STEMI patients

Cutting-edge vascular implant technology available at PinnacleHealth for patients with claudication

Acute mesenteric ischemia can be treated with balloon angioplasty

Stenting and surgery equally effective at lowering long-term risk of stroke

ACC, AHA support implementation of proposed cardiovascular measures, with reservations

Heart attack patients experiencing cardiogenic shock at higher risk of death in first 60 days post-discharge

New methodology could spare kids from unnecessary heart surgery

Ultrasound-activated microbubbles help preserve healthy heart tissue

QT Vascular reports initial results from first-in-human study of Chocolate Heart drug-coated balloon

Heart attack patients with bypass history more likely to have delayed treatment

Restoring blood flow quickly after heart attack symptoms appear may help reduce heart damage

New MRI-based technology could help identify patients at risk of recurrent stroke

Treatment with antiplatelet therapy does not reduce pain crises in children with sickle cell disease

‘More is better’ for medical management of acute stroke

New treatment may help patients with chronic renovascular disease

North Shore-LIJ researcher compares safety benefits two blood-thinning medications

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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