Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Meta-analysis confirms complete failure of hydroxychloroquine/chloroquine as a COVID-19 treatment

Researchers investigate the efficacy of hydroxychloroquine and chloroquine in the treatment of patients hospitalized with COVID-19.

17 Jan 2022

Researchers investigate the role of a key component of the circadian clock in heart disease

Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition.

17 Jan 2022

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours - a feat that's nearly unheard of in standard clinical care.

13 Jan 2022

Long-term use of blood pressure medication could be contributing to kidney damage

New kidney research from the University of Virginia School of Medicine is raising concerns that long-term use of drugs commonly prescribed to treat high-blood pressure and heart failure could be contributing to kidney damage.

12 Jan 2022

Psychotropic drugs are commonly used by patients with heart disease, study shows

Antidepressants and other psychiatric medications are associated with an almost doubled risk of premature death in patients with heart conditions, according to research published today in the European Journal of Cardiovascular Nursing, a journal of the European Society of Cardiology (ESC).

11 Jan 2022

Higher olive oil consumption linked with lower risk of cardiovascular disease, cancer mortality

Consuming more than 7 grams (>1/2 tablespoon) of olive oil per day is associated with lower risk of cardiovascular disease mortality, cancer mortality, neurodegenerative disease mortality and respiratory disease mortality, according to a study publishing today in the Journal of the American College of Cardiology.

10 Jan 2022

Fewer than 1 in 5 U.S. adults with Type 2 diabetes meet targets to reduce heart disease risk

Fewer than 1 in 5 adults with Type 2 diabetes in the U.S. are meeting targets to reduce heart disease risk. Fortunately, available therapies can help when combined with new approaches that address social determinants of health and other barriers to care, according to a new American Heart Association scientific statement published today in the Association's flagship journal Circulation.

10 Jan 2022

Comparison of COVID-19 and influenza-associated complications

Researchers compare the number, types, and risk for complications among COVID-19 and influenza patients using claims data.

9 Jan 2022

Association of obstructive sleep apnea with hospitalization due to COVID-19

Researchers report that OSA is an independent risk factor for severe COVID-19.

7 Jan 2022

In vivo generation of engineered CAR T cells can reduce fibrosis and restore cardiac function after heart injury

A novel immunotherapy strategy using in vivo generation of transient engineered chimeric antigen receptor (CAR) T cells, through the delivery of modified mRNA, can reduce fibrosis and restore cardiac function in a mouse model of heart failure, researchers report.

6 Jan 2022

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

An experimental immunotherapy can temporarily reprogram patients' immune cells to attack a specific target via only a single injection of messenger RNA (mRNA), similar to the mRNA-based COVID-19 vaccines, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

6 Jan 2022

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Not too long ago the idea of taking, for instance a skin cell and transforming it into a muscle cell was unthinkable. About 10 years ago, however, revolutionary research showed that it is indeed possible to reprogram differentiated adult cells into other types fully capable of conducting new functions.

6 Jan 2022

LIVE-AIR trial demonstrates efficacy of Lenzilumab for treatment of COVID patients with decreased oxygen saturation

The LIVE-AIR phase 3 clinical trial is associated with early treatment of hyperinflammatory response with the humanized monoclonal antibody lenzilumab in COVID-19 patients with decreased oxygen saturation. The study results are posted to the medRxiv* preprint server.

6 Jan 2022

Erectile dysfunction medication found to intensify abdominal aortic aneurysms in mice

In a laboratory study in mice, sildenafil, a commonly used erectile dysfunction medication, was found to worsen abdominal aortic aneurysms, indicating additional research may be needed to determine if the medication may have the same effect on people, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

5 Jan 2022

Both symptomatic and asymptomatic COVID-19 associated with increased risk of cardiovascular events

Researcers determine the risk of symptomatic and asymptomatic SARS-CoV-2 infection on post-acute cardiovascular events and all-cause mortality.

4 Jan 2022

Genomic variant may help predict which patients will experience chemotherapy-induced cardiotoxicity

A team of investigators have discovered a genomic variant that may help clinicians predict which patients will experience cardiotoxicity from a widely used chemotherapy drug, according to a Northwestern Medicine study published in Circulation.

3 Jan 2022

Researchers discover new function of protein tBID

The protein tBID can trigger programmed cell death (apoptosis) by inducing damage in the energy suppliers of the cells, the mitochondria. Apoptosis is essential for maintaining tissue balance.

21 Dec 2021

Understanding SARS-CoV-2-induced systemic amyloidosis

A new study proposed that inflammation combined with aggregates of amyloidogenic peptides of SARS-CoV-2 S proteins might induce systemic amyloidosis.

21 Dec 2021

Study shows risk of long-term impact of COVID-19 on patients with cardiovascular diseases and diabetes mellitus

British researchers analyze the net effect of COVID-19 on cardiometabolic outcomes over one month, three months, and twelve months.

19 Dec 2021

As hospitals fill up, paramedics spend more time moving patients, less on emergencies

The night after Thanksgiving, a small ambulance service that covers a huge swath of southwestern Colorado got a call that a patient needed an emergency transfer from the hospital in Gunnison to a larger one with an intensive care unit 65 miles away in Montrose.

17 Dec 2021

Heart Failure News and Research

Further Reading

Meta-analysis confirms complete failure of hydroxychloroquine/chloroquine as a COVID-19 treatment

Researchers investigate the role of a key component of the circadian clock in heart disease

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

Long-term use of blood pressure medication could be contributing to kidney damage

Psychotropic drugs are commonly used by patients with heart disease, study shows

Higher olive oil consumption linked with lower risk of cardiovascular disease, cancer mortality

Fewer than 1 in 5 U.S. adults with Type 2 diabetes meet targets to reduce heart disease risk

Comparison of COVID-19 and influenza-associated complications

Association of obstructive sleep apnea with hospitalization due to COVID-19

In vivo generation of engineered CAR T cells can reduce fibrosis and restore cardiac function after heart injury

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

LIVE-AIR trial demonstrates efficacy of Lenzilumab for treatment of COVID patients with decreased oxygen saturation

Erectile dysfunction medication found to intensify abdominal aortic aneurysms in mice

Both symptomatic and asymptomatic COVID-19 associated with increased risk of cardiovascular events

Genomic variant may help predict which patients will experience chemotherapy-induced cardiotoxicity

Researchers discover new function of protein tBID

Understanding SARS-CoV-2-induced systemic amyloidosis

Study shows risk of long-term impact of COVID-19 on patients with cardiovascular diseases and diabetes mellitus

As hospitals fill up, paramedics spend more time moving patients, less on emergencies

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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