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Inflammatory marker targeted in ear infection

Systemic injection of an antibody against granulocyte/macrophage colony-stimulating factor inhibits middle-ear inflammation induced by lipopolysaccharide in mice, study findings show.

3 Dec 2012

Study to discover exactly how intravenous immune globulin treatments work

Immune globulin replacement began decades ago as a treatment for patients who could not make their own protective antibodies, but has proven to have much broader benefits than originally expected.

22 Nov 2012

University of Liverpool to conduct immunoglobulin clinical study for complex regional pain syndrome

Scientists at the University of Liverpool are leading a -1.5 million project to study `immunoglobulin', a type of drug which has been shown to ease complex regional pain syndrome (CRPS).

22 Nov 2012

Triclosan exposure linked to allergies in children

Norwegian children with high levels of urinary triclosan are more likely to have allergies than children with lower levels, report researchers in Allergy.

15 Nov 2012

Triclosan can contribute to increased risk of allergies in children

Triclosan - an antibacterial chemical found in toothpaste and other products - can contribute to an increased risk of allergy development in children. This comes from the Norwegian Environment and Childhood Asthma Study, in which the Norwegian Institute of Public Health is involved. Similar results are reported in the USA.

15 Nov 2012

Overcleanliness in childhood may increase risk for peanut allergy

An increased incidence of peanut allergy in children from more wealthy families supports the “hygiene hypothesis” that overcleanliness may promote the onset of childhood allergies, say US researchers.

9 Nov 2012

Overweight, smoking add to rheumatoid arthritis risk

Lifestyle changes could reduce the risk for rheumatoid arthritis in patients predisposed to the condition, Dutch researchers suggest.

5 Nov 2012

Autoantibody aids identification of hyperexcitability disorders

Researchers have found that testing for a glycine receptor autoantibody aids the identification of a broad spectrum of autoimmune brainstem/spinal cord hyperexcitability disorders.

29 Oct 2012

Researchers identify how mosquito's immune system attacks specific infections

Researchers at the Johns Hopkins Bloomberg School of Public Health have determined a new mechanism by which the mosquitoes' immune system can respond with specificity to infections with various pathogens, including the parasite that causes malaria in humans, using one single gene.

20 Oct 2012

Early exposure to traffic-related air pollution affects respiratory health in children

Exposure to ambient air pollution from traffic during infancy is associated with lung function deficits in children up to eight years of age, particularly among children sensitized to common allergens, according to a new study.

12 Oct 2012

Pesticide exposure may trigger food allergies

Results from the US National Health and Nutrition Examination Survey suggest that high exposure to dichlorophenols, chemicals found in pesticides and used for chlorinating water, may increase a person’s risk for developing food allergies.

5 Oct 2012

Absence of proteinuria good prognostic sign in IgA nephropathy

The presence of normal renal function and minor urinary abnormalities indicates a good long-term prognosis among Caucasian patients with immunoglobulin A nephropathy, say Spanish researchers.

24 Sep 2012

Researchers identify subgroups of B cells in MYC-positive germinal centers

Germinal centers are sites in the organs of the lymphatic system, formed during the course of an immune response to infection, where B cells intensely proliferate and modify their DNA in order to produce antibodies specific for the pathogen. However, it is known that the vast majority of lymphomas derive from the B cells at the germinal centers.

24 Sep 2012

Cedars-Sinai neurologist to study MS-related depression

Living every day with a life-changing illness is discouraging enough, but Maryam Hosseinzadeh is one of 400,000 people in the United States battling multiple sclerosis, a disorder that by changing the brain's makeup appears capable of generating the secondary ill of depression.

21 Sep 2012

Loss of IGSF1 gene function causes central hypothyroidism

Loss of function in the X-linked immunoglobulin superfamily member 1 (IGSF1) gene causes central hypothyroidism, testicular enlargement, and variable prolactin deficiency, according to data presented at the 82nd Annual Meeting of the American Thyroid Association in Québec City, Québec, Canada.

21 Sep 2012