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Early-acting autophagy genes extend lifespan through alternative "garbage disposal" pathway in neurons

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and Rutgers University have uncovered possible novel functions for various autophagy genes, which may control different forms of disposal including misfolded proteins - and ultimately affect aging.

4 Jan 2024

Salk scientists map brain circuit triggering the crippling panic attacks

Overwhelming fear, sweaty palms, shortness of breath, rapid heart rate - these are the symptoms of a panic attack, which people with panic disorder have frequently and unexpectedly.

4 Jan 2024

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Over the past decades, scientists have made substantial progress unveiling the underlying mechanisms behind many psychiatric disorders.

4 Jan 2024

Retinotopic coding bridges perception and memory in the brain, study finds

Study reveals that retinotopic coding in the brain cortex plays a crucial role in processing visual information from the retina, influencing both perception and memory systems.

3 Jan 2024

Brain's immune cells may be a key target for preventing cognitive deficits after radiation exposure

Researchers at the Del Monte Institute for Neuroscience at the University of Rochester find that microglia - the brain's immune cells - can trigger cognitive deficits after radiation exposure and may be a key target for preventing these symptoms.

3 Jan 2024

Mapping tiny corneal nerves to untangle ocular mysteries

Consider the cornea if you will – and most people won't unless they're having a problem. It is the transparent front surface of the eye which allows vision by focusing light as it enters.

3 Jan 2024

Unlocking the appetite-stimulating secrets of cannabis through rodent brain studies

Study reveals that cannabinoid-1 receptor-expressing neurons in the mediobasal hypothalamus play a key role in the appetite-stimulating effects of inhaled cannabis in rodents, offering insights into potential treatments for anorexia.

2 Jan 2024

Calcium channel blockers reverse muscle weakness in animal model of myotonic dystrophy type 1

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these symptoms in animal models of the disease.

2 Jan 2024

Scientists link growth hormone to anxiety and fear memory through specific neuron group

Growth hormone (GH) acts on many tissues throughout the body, helping build bones and muscles, among other functions.

2 Jan 2024

Previously unidentified protein variant shields against Parkinson's disease

A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson's disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis School of Gerontology study.

2 Jan 2024

Study reveals novel neural coding mechanism for transferring perceptual information to memory

Our memories are rich in detail: we can vividly recall the color of our home, the layout of our kitchen, or the front of our favorite café. How the brain encodes this information has long puzzled neuroscientists.

2 Jan 2024

Fox urine compound effectively repels flies through multisensory activation

Crop damage in agriculture and the transmission of vector-borne diseases by insect pests have become worldwide threat nowadays.

25 Dec 2023

Unraveling nuanced roles of JAK inhibitors in inflammation

Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.

21 Dec 2023

Study reveals brain's built-in mechanism for stitching experiences into memories

Scientists at NTNU's Kavli Institute for Systems Neuroscience in Norway have discovered a pattern of activity in the brain that serves as a template for building sequential experiences.

20 Dec 2023

UW-Madison technology unveils autism gene's impact on early brain structure

Technology developed at the University of Wisconsin–Madison to grow "rosettes" of brain and spinal tissue gives scientists new ways to study the growing human brain, including a recent study of how genetic mutations linked to autism affect early stages of human brain development.

20 Dec 2023

Gamma stimulation may improve memory and cognition in people with Alzheimer's disease

A surprising MIT study published in Nature at the end of 2016 helped to spur interest in the possibility that light flickering at the frequency of a particular gamma-band brain rhythm could produce meaningful therapeutic effects for people with Alzheimer's disease.

20 Dec 2023

Study reveals extensive postnatal neuronal migration in human entorhinal cortex

The human brain continues to be built after we are born for far longer than previously recognized, suggests research by Shawn Sorrells, assistant professor of neuroscience in the Kenneth P. Dietrich School of Arts and Sciences.

20 Dec 2023

UVA Alzheimer's study pinpoints how tau protein damages brain cells

University of Virginia Alzheimer's researchers have discovered how harmful tau proteins damage the essential operating instructions for our brain cells, a finding which could lead to new treatments.

20 Dec 2023

Study deciphers how misfolded protein drives dopaminergic neuron loss in Parkinson's

A so-called pathological protein long associated with Parkinson's disease has been found in a new study to trigger cells to increase protein synthesis, an event that eventually kills the subset of brain cells that die off in this neurodegenerative condition.

20 Dec 2023

Breakthrough in Parkinson's research: Scientists identify protein synthesis pathway as culprit

19 Dec 2023

Neurons News and Research

Early-acting autophagy genes extend lifespan through alternative "garbage disposal" pathway in neurons

Salk scientists map brain circuit triggering the crippling panic attacks

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Retinotopic coding bridges perception and memory in the brain, study finds

Brain's immune cells may be a key target for preventing cognitive deficits after radiation exposure

Mapping tiny corneal nerves to untangle ocular mysteries

Unlocking the appetite-stimulating secrets of cannabis through rodent brain studies

Calcium channel blockers reverse muscle weakness in animal model of myotonic dystrophy type 1

Scientists link growth hormone to anxiety and fear memory through specific neuron group

Previously unidentified protein variant shields against Parkinson's disease

Study reveals novel neural coding mechanism for transferring perceptual information to memory

Fox urine compound effectively repels flies through multisensory activation

Unraveling nuanced roles of JAK inhibitors in inflammation

Study reveals brain's built-in mechanism for stitching experiences into memories

UW-Madison technology unveils autism gene's impact on early brain structure

Gamma stimulation may improve memory and cognition in people with Alzheimer's disease

Study reveals extensive postnatal neuronal migration in human entorhinal cortex

UVA Alzheimer's study pinpoints how tau protein damages brain cells

Study deciphers how misfolded protein drives dopaminergic neuron loss in Parkinson's

Breakthrough in Parkinson's research: Scientists identify protein synthesis pathway as culprit

Neuroscience - Third Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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