Genes News and Research

RSS

TGen study reveals genetic origins of breast cancer that spreads to brain

The Translational Genomics Research Institute (TGen) has uncovered possible genetic origins of breast cancer that spreads to the brain, according to a first-of-its-kind study published in the scientific journal PLOS ONE.

11 Feb 2014

Researchers discover biological switch that regulates protein that causes fatty liver disease in mice

Studying a cycle of protein interactions needed to make fat, Johns Hopkins researchers say they have discovered a biological switch that regulates a protein that causes fatty liver disease in mice.

11 Feb 2014

Two oncogenes work together to sustain population of cells in lung squamous cell carcinoma

Patients with a common form of lung cancer — lung squamous cell carcinoma — have very few treatment options. That situation may soon change.

10 Feb 2014

Researchers find biological weakness in the workings of mutated gene involved in human cancers

NYU Langone Medical Center researchers have found a biological weakness in the workings of the most commonly mutated gene involved in human cancers, known as mutant K-Ras, which they say can be exploited by drug chemotherapies to thwart tumor growth.

10 Feb 2014

Findings may help physicians choose precise treatments for women with advanced breast cancer

The first large-scale study testing all the DNA—the entire genome—of tumour cells from more than 400 women with advanced breast cancer has identified individuals with a good chance of benefiting from specific treatments already being tested in clinical trials.

10 Feb 2014

New study co-led by scientists sheds light on role of genes, blood lipid levels in cardiovascular health

New genetic evidence strengthens the case that one well-known type of cholesterol is a likely suspect in causing heart disease, but also casts further doubt on the causal role played by another type.

10 Feb 2014

New study tracks spread of H5N1 variant in Egypt recently identified as major epicenter for virus

Since its first identification in Asia, highly pathogenic avian influenza-H5N1-has caused significant alarm in the scientific community. While the virus' primary target is birds-tens of millions have already died from it-it is capable of infecting mammals, including humans, causing serious illness and a frightening rate of mortality.

10 Feb 2014

Scientists develop new approach to design drugs from genome sequence

In research that could ultimately lead to many new medicines, scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a potentially general approach to design drugs from genome sequence. As a proof of principle, they identified a highly potent compound that causes cancer cells to attack themselves and die.

10 Feb 2014

Optogenetics technique allows scientists to control neurons' electrical activity

Optogenetics is a technique that allows scientists to control neurons' electrical activity with light by engineering them to express light-sensitive proteins. Within the past decade, it has become a very powerful tool for discovering the functions of different types of cells in the brain.

10 Feb 2014

Study identifies seven new genetic regions associated with type 2 diabetes

Seven new genetic regions associated with type 2 diabetes have been identified in the largest study to date of the genetic basis of the disease.

9 Feb 2014

Study points to molecular pathway to treat recurring, deadly malignancies

Analyzing the genomes of twin 3-year-old sisters – one healthy and one with aggressive leukemia – led an international team of researchers to identify a novel molecular target that could become a way to treat recurring and deadly malignancies.

9 Feb 2014

Researchers shed light on role of genes and blood lipid levels in cardiovascular health

New genetic evidence strengthens the case that one well-known type of cholesterol is a likely suspect in causing heart disease, but also casts further doubt on the causal role played by another type. The findings may guide the search for improved treatments for heart disease.

9 Feb 2014

Researchers identify protein that regulates how genetic information transcribed from DNA to mRNA

Molecular biologists from Indiana University are part of a team that has identified a protein that regulates the information present in a large number of messenger ribonucleic acid molecules that are important for carrying genetic information from DNA to protein synthesis.

7 Feb 2014

Researchers examine how toxin triggers motor neuron death

In most cases of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, a toxin released by cells that normally nurture neurons in the brain and spinal cord can trigger loss of the nerve cells affected in the disease, Columbia researchers reported today in the online edition of the journal Neuron.

7 Feb 2014

Findings could open door to development of new therapies for treatment of prostate cancer

SCIENTISTS at the University of York have discovered how the prostate gland develops for the first time, according to research published today (Thursday, February 6) in Stem Cell Reports.

7 Feb 2014

Researchers identify histone proteins that may be key to generate induced totipotent stem cells

One major challenge in stem cell research has been to reprogram differentiated cells to a totipotent state. Researchers from RIKEN in Japan have identified a duo of histone proteins that dramatically enhance the generation of induced pluripotent stem cells (iPS cells) and may be the key to generating induced totipotent stem cells.

7 Feb 2014

Rare and de novo mutations flesh out schizophrenia picture

Two studies in Nature show that rare disruptive and de novo mutations may contribute to the pathophysiology of schizophrenia.

6 Feb 2014

Study explores link between facial attractiveness and physical performance in professional cyclists

In a range of species, females show clear preferences when it comes to the choice of their partner - they decide on the basis of external features like antler size or plumage coloration whether a male will be a good father to her offspring, or whether he will provide them with good genes.

6 Feb 2014

Research examines differences between male and female brain that contributes to violent behavior

Human behaviors such as violence depend on interactions in the brain between genetic and environmental factors. An individual may be more vulnerable to developing violent behaviors if they have predisposing factors and are then exposed to stress, abuse, or other triggers, especially early in life.

6 Feb 2014

Chinese scientists confirm world’s first case of human infection with new avian influenza virus

Scientists from China report in The Lancet on the world’s first confirmed case of human infection with a new avian influenza A H10N8 virus in a 73-year-old woman who died from the infection.

6 Feb 2014

Genes News and Research

TGen study reveals genetic origins of breast cancer that spreads to brain

Researchers discover biological switch that regulates protein that causes fatty liver disease in mice

Two oncogenes work together to sustain population of cells in lung squamous cell carcinoma

Researchers find biological weakness in the workings of mutated gene involved in human cancers

Findings may help physicians choose precise treatments for women with advanced breast cancer

New study co-led by scientists sheds light on role of genes, blood lipid levels in cardiovascular health

New study tracks spread of H5N1 variant in Egypt recently identified as major epicenter for virus

Scientists develop new approach to design drugs from genome sequence

Optogenetics technique allows scientists to control neurons' electrical activity

Study identifies seven new genetic regions associated with type 2 diabetes

Study points to molecular pathway to treat recurring, deadly malignancies

Researchers shed light on role of genes and blood lipid levels in cardiovascular health

Researchers identify protein that regulates how genetic information transcribed from DNA to mRNA

Researchers examine how toxin triggers motor neuron death

Findings could open door to development of new therapies for treatment of prostate cancer

Researchers identify histone proteins that may be key to generate induced totipotent stem cells

Rare and de novo mutations flesh out schizophrenia picture

Study explores link between facial attractiveness and physical performance in professional cyclists

Research examines differences between male and female brain that contributes to violent behavior

Chinese scientists confirm world’s first case of human infection with new avian influenza virus

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics