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Researchers make first link between menopause, smoking and genetic variations in white women

New research is lighting up yet another reason for women to quit smoking. In a study published online in the journal Menopause, researchers from the Perelman School of Medicine at the University of Pennsylvania report the first evidence showing that smoking causes earlier signs of menopause - in the case of heavy smokers, up to nine years earlier than average - in white women with certain genetic variations.

5 Feb 2014

Study: Sensitivity to pain could be altered by person's lifestyle and environment

Researchers at King's College London have discovered that sensitivity to pain could be altered by a person's lifestyle and environment throughout their lifetime. The study is the first to find that pain sensitivity, previously thought to be relatively inflexible, can change as a result of genes being switched on or off by lifestyle and environmental factors - a process called epigenetics, which chemically alters the expression of genes.

5 Feb 2014

Scientists reveal important degradation pathway of sulpho-glucose

By discovering sulpho-glycolysis, researchers of the University of Konstanz reveal an important degradation pathway.

5 Feb 2014

Professor wins Wiley Prize for discovering how cells sense, respond to low oxygen conditions

The 13th annual Wiley Prize in Biomedical Sciences was awarded to Gregg Semenza, M.D., Ph.D., for his contribution to discovering how cells sense and respond to low oxygen conditions.

5 Feb 2014

Splicing findings offer lung cancer clues

Researchers from Spain have identified several new splicing events regulated by the oncogenic splicing factor SRSF1 in lung cancer, suggesting that their dysregulation is involved in the pathogenesis of the disease.

4 Feb 2014

Biotheranostics launches complete genomic tests for metastatic cancer patients

bioTheranostics, Inc., today introduced the bioT3 Metastatic Cancer Solution, a suite of genomic-based tests that provide personalized diagnostic information and therapeutic guidance for metastatic cancer patients across the continuum of care.

4 Feb 2014

Gene involved in inflammation, blood clotting associated with cerebral palsy, death in very preterm babies

In a study to be presented on Feb. 6 at 2:45 p.m. CST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting-, in New Orleans, researchers will report that a variant in SERPINE1, a gene involved in inflammation and blood clotting, is associated with cerebral palsy and death in very preterm babies.

4 Feb 2014

Research: SSeCKS/AKAP12 gene key inhibitor of prostate cancer metastasis

New evidence reported by researchers at Roswell Park Cancer Institute (RPCI) lends support to the hypothesis that the SSeCKS/AKAP12 gene is a key inhibitor of prostate cancer metastasis.

4 Feb 2014

Chemical "signature" in blood may predict which AML patients would benefit from chemotherapy

Researchers at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center have found a chemical "signature" in blood-forming stem cells that predicts whether patients with acute myeloid leukemia (AML) will respond to chemotherapy.

4 Feb 2014

Researchers discover new signaling pathway that could impact treatment of autoinflammatory diseases

Researchers from Virginia Commonwealth University (VCU) Massey Cancer Center have discovered a new signaling pathway in sterile inflammation that could impact the treatment of diseases such as cancer, multiple sclerosis and rheumatoid arthritis.

4 Feb 2014

Findings may help doctors personalize preterm birth prevention treatments

New research findings may soon help doctors personalize preterm birth prevention treatments by identifying which women at higher risk for preterm birth will be helped by progesterone injections.

4 Feb 2014

Researchers discover genetic function that helps "tumor suppressor" genes to prevent cancer

Researchers at Oregon State University have discovered a genetic function that helps one of the most important "tumor suppressor" genes to do its job and prevent cancer.

4 Feb 2014

Addressing antibiotic resistance: an interview with Professor Otto Cars, Uppsala University, Sweden

Antibiotic resistance is a consequence of antibiotic use. Bacteria adapt to the threat of antibiotics using mechanisms to overcome the drug. These bacteria, which we call resistant bacteria, then survive.

3 Feb 2014

Researchers find liver tumors in mice exposed to BPA during gestation and nursing

In one of the first studies to show a significant association between BPA and cancer development, University of Michigan School of Public Health researchers have found liver tumors in mice exposed to the chemical via their mothers during gestation and nursing.

3 Feb 2014

Vitamin C and E supplements blunt endurance training

Vitamin C and E supplements may blunt the improvement of muscular endurance - by disrupting cellular adaptions in exercised muscles - suggests a new study published today [3 February] in The Journal of Physiology.

3 Feb 2014

Ronald G. Crystal wins Pioneer Award from Human Gene Therapy

In recognition of his seminal work on adenoviral vectors, which accelerated the translation of gene therapy from the research laboratory to the clinic, Ronald G. Crystal, MD (Weill Cornell Medical College, Cornell University, New York City), has received a Pioneer Award from Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

31 Jan 2014

Study describes new tack in treatment of lung adenocarcinomas

The most common genetic subtype of lung cancer, which has long defied treatment with targeted therapies, has had its growth halted by a combination of two already-in-use drugs in laboratory and animal studies, setting the stage for clinical trials of the drugs in patients, researchers at Dana-Farber Cancer Institute and other scientists report in a new study.

31 Jan 2014

Genes News and Research

Researchers make first link between menopause, smoking and genetic variations in white women

Study: Sensitivity to pain could be altered by person's lifestyle and environment

Scientists reveal important degradation pathway of sulpho-glucose

Professor wins Wiley Prize for discovering how cells sense, respond to low oxygen conditions

Splicing findings offer lung cancer clues

Biotheranostics launches complete genomic tests for metastatic cancer patients

Gene involved in inflammation, blood clotting associated with cerebral palsy, death in very preterm babies

Research: SSeCKS/AKAP12 gene key inhibitor of prostate cancer metastasis

Chemical "signature" in blood may predict which AML patients would benefit from chemotherapy

Researchers discover new signaling pathway that could impact treatment of autoinflammatory diseases

Findings may help doctors personalize preterm birth prevention treatments

Researchers discover genetic function that helps "tumor suppressor" genes to prevent cancer

Addressing antibiotic resistance: an interview with Professor Otto Cars, Uppsala University, Sweden

Researchers find liver tumors in mice exposed to BPA during gestation and nursing

Vitamin C and E supplements blunt endurance training

Ronald G. Crystal wins Pioneer Award from Human Gene Therapy

Study describes new tack in treatment of lung adenocarcinomas

Drugs that modify DNA structure may be beneficial for treating Alzheimer's disease

Sub-optimal sleep may activate depressive genes, increase risk for major depression

RNAi-based screening offers MPM treatment hope

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