Laboratory News and Research

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Study shows how cancer cells pursue path toward greater concentrations of oxygen

Cancer cells need oxygen to survive, as do most other life forms, but scientists had never tracked their search for oxygen in their early growth stages until now -- a step toward a deeper understanding of one way cancer spreads that could help treat the disease.

3 Aug 2016

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Cancer immunotherapy drugs that block the inhibitory PD-1 pathway have shown success in clinical trials and are now FDA-approved for melanoma, lung cancer and bladder cancer. Yet many patients' tumors do not respond to these drugs.

3 Aug 2016

New Valley Fever testing technology developed by TGen and NAU receives U.S. patent

Valley Fever, a potentially deadly dust-borne fungal disease, should be easier to diagnose and treat thanks to a testing technology developed by the Translational Genomics Research Institute and Northern Arizona University, and now protected by a patent issued today by the U.S. Patent and Trademark Office.

3 Aug 2016

New study provides projections for Zika outbreaks in the Americas through January 2017

With the report from Florida Gov. Rick Scott on Monday that 14 people in the state have been infected with the Zika virus most likely through mosquito transmission, the concern about outbreaks in the U.S. has intensified.

3 Aug 2016

Penn's ADCC receives $8.8 million grant to continue research on treatment for AD and related dementias

The University of Pennsylvania's Alzheimer's Disease Core Center has been awarded an estimated $8.8 million over five years from the National Institute on Aging to continue its mission of investigating mechanisms, diagnostics, treatments and strategies for Alzheimer's Disease (AD) and related dementias including Parkinson's disease (PD), Parkinson's disease dementia (PDD), Lewy Body dementia (LBD) and frontotemporal lobar degeneration (FTLD).

3 Aug 2016

Advances in head and neck cancer treatments: an interview with Prof. Argiris

Patients with head and neck cancer usually present with locally advanced disease and often require more than one type of treatment, which may include surgery, radiotherapy, and chemotherapy.

3 Aug 2016

Biologists discover male-harming mtDNA mutant that substantiates mother's curse hypothesis

There is new evidence that the "mother's curse" - the possibility that moms may transmit genes to their children that harm their sons but not their daughters - holds true in animals.

3 Aug 2016

New review highlights usefulness of BTMs in monitoring efficacy of osteoporosis treatment

A new review published by a joint scientific working group of the International Federation of Clinical Chemistry and Laboratory Medicine and the International Osteoporosis Foundation finds that current evidence continues to support the potential for bone turnover markers (BTMs) to provide clinically useful information for monitoring osteoporosis treatment.

3 Aug 2016

E. coli bacteria capable of beneficial mutations at more variable rates than previously thought

Scientists studying how microbes evolve have long assumed that nearly all new genetic mutations get passed down at a predictable pace and usually without either helping or hurting the microbe in adapting to its environment.

2 Aug 2016

Research finding opens door to potential clinical approaches that may boost body's ability to battle cancer

The microenvironment that supports a cancerous tumor also starves the immune cells that the body sends in to destroy the cancer, University of Pittsburgh Cancer Institute scientists revealed in a discovery that holds the potential to significantly boost the performance of breakthrough immunotherapy drugs.

2 Aug 2016

Vaccines unsuccessful in protecting obese mice against influenza infections, study finds

A study led by St. Jude Children's Research Hospital found that obese mice are not protected against influenza infections by vaccines that include adjuvants, raising concerns about vaccine effectiveness in obese humans who are known to be at an increased risk for severe flu. The findings appear today in the scientific journal mBio.

2 Aug 2016

Bibby Scientific announces launch of Jenway’s new 7200 visible spectrophotometer for laboratory use

Bibby Scientific Ltd announced today that Jenway, a leading UK manufacturer of analytical laboratory instruments, has launched the new 7200 visible scanning spectrophotometer.

From Cole Parmer Limited 2 Aug 2016

Scientists observe reaction of neurons in real-time after concussive trauma

A team of Brown University researchers has been able to watch in real time what happens to neurons after they experience the kinds of forces involved in a blow to the head.

2 Aug 2016

GW researchers identify new way to regulate chronic toxoplasmosis

New research critical to treatment for chronic toxoplasmosis, one of the most common parasitic diseases worldwide, was published in the Journal of Experimental Medicine.

2 Aug 2016

Iron-containing catalysts can alter amino acids to help develop new drug candidates

For medicinal chemists, making tweaks to peptide structures is key to developing new drug candidates. Now, researchers have demonstrated that two iron-containing small-molecule catalysts can help turn certain types of amino acids -- the building blocks of peptides and proteins -- into an array of potential new forms, even when part of a larger peptide, while preserving a crucial aspect of their chemistry: chirality, or "handedness."

2 Aug 2016

Cell-free DNA test could help identify liver transplant patients with acute rejection

Today, researchers presented findings at the 68th AACC Annual Scientific Meeting that DNA found circulating in the bloodstream—known as cell-free DNA—can be used to identify liver transplant patients with acute rejection with greater accuracy than conventional liver function tests.

1 Aug 2016

WHO supports deployment of mobile lab for fast-tracking diagnosis of yellow fever

“Treating a yellow fever patient is reliant on having the right diagnosis. This is dependent on having the necessary laboratory capacity to quickly identify the disease,” says Dr Pierre Formenty, an expert in haemorrhagic fevers at WHO and Manager of the Emerging Dangerous Pathogens Laboratory Network.

1 Aug 2016

AACC introduces new journal to deliver advancements in translational laboratory medicine research

AACC, a global scientific and medical professional organization dedicated to better health through laboratory medicine, is pleased to announce the launch of its new journal, The Journal of Applied Laboratory Medicine: An AACC Publication.

1 Aug 2016

IFCC enhances quality of diagnosis and therapy to improve clinical outcomes for patients worldwide

The International Federation of Clinical Chemistry and Laboratory Medicine is an organization of 90 Full Members National Societies, 12 Affiliate Members National Societies and 46 Corporate Members serving laboratory professionals worldwide and representing 45,000 laboratory medicine specialists world-wide.

1 Aug 2016

Ortho Clinical Diagnostics to showcase seven posters of vital tests, six products at AACC meeting

Ortho Clinical Diagnostics today announced it will present seven scientific posters on its assays and display six products at its booth at the 2016 American Association for Clinical Chemistry annual meeting.

30 Jul 2016

Laboratory News and Research

Study shows how cancer cells pursue path toward greater concentrations of oxygen

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

New Valley Fever testing technology developed by TGen and NAU receives U.S. patent

New study provides projections for Zika outbreaks in the Americas through January 2017

Penn's ADCC receives $8.8 million grant to continue research on treatment for AD and related dementias

Advances in head and neck cancer treatments: an interview with Prof. Argiris

Biologists discover male-harming mtDNA mutant that substantiates mother's curse hypothesis

New review highlights usefulness of BTMs in monitoring efficacy of osteoporosis treatment

E. coli bacteria capable of beneficial mutations at more variable rates than previously thought

Research finding opens door to potential clinical approaches that may boost body's ability to battle cancer

Vaccines unsuccessful in protecting obese mice against influenza infections, study finds

Bibby Scientific announces launch of Jenway’s new 7200 visible spectrophotometer for laboratory use

Scientists observe reaction of neurons in real-time after concussive trauma

GW researchers identify new way to regulate chronic toxoplasmosis

Iron-containing catalysts can alter amino acids to help develop new drug candidates

Cell-free DNA test could help identify liver transplant patients with acute rejection

WHO supports deployment of mobile lab for fast-tracking diagnosis of yellow fever

AACC introduces new journal to deliver advancements in translational laboratory medicine research

IFCC enhances quality of diagnosis and therapy to improve clinical outcomes for patients worldwide

Ortho Clinical Diagnostics to showcase seven posters of vital tests, six products at AACC meeting

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