Genes News and Research

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Researchers suggest new targets may provide druggable alternatives to Ewing's Sarcoma

Ewing's Sarcoma is an aggressive pediatric cancer, most commonly caused by the improper fusion of the gene EWS with the gene FLI1. Though the cause has long been known, therapeutic targeting of this fusion has to date proven very difficult.

22 Jan 2014

Genetic counseling delivered over telephone as effective as face-to-face counseling, says study

Genetic counseling delivered over the telephone is as effective as face-to-face counseling, finds the largest randomized study to date comparing the two methods. The multi-center study, led by researchers at Georgetown Lombardi Comprehensive Cancer Center, was reported today in the Journal of Clinical Oncology.

22 Jan 2014

Damon Runyon Cancer Research Foundation awards $2.25M to six innovative young scientists

The Damon Runyon Cancer Research Foundation announced that six scientists with novel approaches to fighting cancer have been named 2014 recipients of the Damon Runyon-Rachleff Innovation Award. The grant of $450,000 over three years is awarded each year to early career scientists whose projects have the potential to significantly impact the prevention, diagnosis and treatment of cancer.

21 Jan 2014

Irregular sleep timing disrupts daily rhythms of our genes

A new study from the University of Surrey, published today in the journal PNAS (Proceedings of the National Academy of Sciences), found that the daily rhythms of our genes are disrupted when sleep times shift.

21 Jan 2014

Vivaldi Biosciences inks agreement with NIAID to evaluate LAIV candidates against influenza A

Vivaldi Biosciences Inc., a clinical-stage biotechnology company developing live attenuated influenza vaccines against seasonal and pandemic influenza, today announced that it has signed a Cooperative Research and Development Agreement with the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to generate and evaluate in preclinical studies LAIV candidates against influenza A(H7N9).

21 Jan 2014

Childhood brain cancer (ETMR/ETANTR): an interview with Dr. Nada Jabado, Department of Pediatrics at McGill University

Embryonal tumours with multilayered rosettes (ETMR) are rare, deadly brain tumours that affect mainly children below the age of 4 years. There are 300 cases reported but probably there are many more as this tumour is often misdiagnosed.

21 Jan 2014

LUMC receives grant for research into influence of 'the family' on child mortality, fertility and life expectancy

Radboud University historians and ageing researchers from Leiden University Medical Center (LUMC) will be receiving a grant of over 800,000 euros for research into the influence of 'the family' on child mortality, fertility and life expectancy over the last two hundred years.

21 Jan 2014

Splicing factor SRSF6 promotes hyperplasia of sensitized skin

Normally, tissue injury triggers a mechanism in cells that tries to repair damaged tissue and restore the skin to a normal, or homeostatic state. Errors in this process can give rise to various problems, such as chronic inflammation, which is a known cause of certain cancers.

21 Jan 2014

Researchers identify molecular mechanism by which cocaine alters brain's reward circuits, causes addiction

Researchers from the Icahn School of Medicine at Mount Sinai have identified a new molecular mechanism by which cocaine alters the brain's reward circuits and causes addiction.

21 Jan 2014

Gene therapy edges closer for Parkinson’s disease

Lentiviral vector-based gene therapy is well tolerated and may improve motor function in patients with Parkinson’s disease, shows an open-label study published in The Lancet.

20 Jan 2014

Going barefoot contributes to hookworm infections

Going barefoot in parts of Africa, Asia and South America contributes to hookworm infections, which afflict an estimated 700 million of the world's poor. The parasitic worm lives in the soil and enters the body through the feet. By feeding on victims' blood, the worms cause anemia and, in children, stunted growth and learning problems.

20 Jan 2014

TSRI scientists use new technique to discover two antibodies that protect human cells from cold virus

Scientists at The Scripps Research Institute (TSRI) have demonstrated the power of a new drug discovery technique, which allows them to find-relatively quickly and cheaply-antibodies that have a desired effect on cells. The TSRI scientists used the technique to discover two antibodies that protect human cells from a cold virus.

20 Jan 2014

Breakthrough technology could provide new approach for treatment of chronic wounds

A team of researchers led by an NIBIB grantee at Vanderbilt University has created a biodegradable scaffold that enables sustained, local delivery of gene-silencing factors called siRNA to promote tissue regeneration. The team recently used the scaffold to successfully deliver siRNA to mice in order to locally silence a gene normally responsible for inhibiting blood vessel formation.

20 Jan 2014

Axxam, Cellectis bioresearch partner to offer cell-based assays to Life Science industry

Axxam (Milan), a leading provider of discovery services including assay development for high-throughput screening, and Cellectis bioresearch (Paris), the cell engineering expert, have started a collaboration to offer to the Life Science industry an extensive range of integrated discovery services based on genomic engineering technologies.

19 Jan 2014

BioTime subsidiary releases version 1.5 of LifeMap Discovery

LifeMap Sciences, Inc., a subsidiary of BioTime, Inc., announced today the release of LifeMap Discovery version 1.5. LifeMap Discovery is a state-of-the-art roadmap of embryonic development and stem cell biology.

18 Jan 2014

Gene therapies correct three forms of retinal degenerative diseases

Gene therapies developed by University of Pennsylvania School of Veterinary Medicine researchers have worked to correct different forms of blindness. While effective, the downside to these approaches to vision rescue is that each disease requires its own form of gene therapy to correct the particular genetic mutation involved, a time consuming and complex process.

17 Jan 2014

IRCM researchers show importance of DNA architecture in controlling activity of genes

A study conducted by Marie Kmita's team at the IRCM, in collaboration with Jos-e Dostie at McGill University, shows the importance of the chromatin architecture in controlling the activity of genes, especially those required for proper embryonic development.

17 Jan 2014

Research shows biological link between paternal diet and health of offspring

Research involving rats suggests that there is a biological link between paternal diet, bodyweight and health at the time of conception and the health of his offspring. In a new research report published online in The FASEB Journal, scientists show that if male rats ate a high fat diet, had diabetes and were obese, their offspring had altered gene expression in two important metabolic tissues--pancreas and fat (even though they were not yet obese).

16 Jan 2014

Study explores the role of DNA in predisposing individuals to diseases

A group of international researchers, led by a research fellow in the Harvard Medical School-affiliated Institute for Aging Research at Hebrew SeniorLife, published a paper today in Cell describing a study aimed at better understanding how inherited genetic differences, or variants, predispose certain individuals to develop diseases such as type 2 diabetes.

16 Jan 2014

RNA sequencing unlocks bipolar secrets

An RNA sequencing study of patients with bipolar disorder has shown altered expression of genes and transcripts, including those involved in neuroplasticity and circadian rhythms.

16 Jan 2014

Genes News and Research

Researchers suggest new targets may provide druggable alternatives to Ewing's Sarcoma

Genetic counseling delivered over telephone as effective as face-to-face counseling, says study

Damon Runyon Cancer Research Foundation awards $2.25M to six innovative young scientists

Irregular sleep timing disrupts daily rhythms of our genes

Vivaldi Biosciences inks agreement with NIAID to evaluate LAIV candidates against influenza A

Childhood brain cancer (ETMR/ETANTR): an interview with Dr. Nada Jabado, Department of Pediatrics at McGill University

LUMC receives grant for research into influence of 'the family' on child mortality, fertility and life expectancy

Splicing factor SRSF6 promotes hyperplasia of sensitized skin

Researchers identify molecular mechanism by which cocaine alters brain's reward circuits, causes addiction

Gene therapy edges closer for Parkinson’s disease

Going barefoot contributes to hookworm infections

TSRI scientists use new technique to discover two antibodies that protect human cells from cold virus

Breakthrough technology could provide new approach for treatment of chronic wounds

Axxam, Cellectis bioresearch partner to offer cell-based assays to Life Science industry

BioTime subsidiary releases version 1.5 of LifeMap Discovery

Gene therapies correct three forms of retinal degenerative diseases

IRCM researchers show importance of DNA architecture in controlling activity of genes

Research shows biological link between paternal diet and health of offspring

Study explores the role of DNA in predisposing individuals to diseases

RNA sequencing unlocks bipolar secrets

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