Genes News and Research

RSS

Scientists establish a goal of creating vaccine gene chip to speed up vaccine testing

Testing the efficacy of vaccines in clinical trials takes years, even decades. Yet challenging infections like HIV, malaria and dengue are striking today. To speed up vaccine testing, scientists at the Emory Vaccine Center have established a goal of creating a "vaccine gene chip."

17 Dec 2013

Research findings point to possible new strategy for treating ALS

Amyotrophic lateral sclerosis, better known as Lou Gehrig's disease, is a devastating illness that gradually robs sufferers of muscle strength and eventually causes a lethal, full-body paralysis. The only drug available to treat the disease extends life spans by a meager three months on average.

17 Dec 2013

PAM50 FDA-cleared breast cancer test to be launched at ARUP Laboratories

The PAM50 breast cancer signature developed at the University of Utah and Huntsman Cancer Institute received FDA approval and will launch at ARUP Laboratories in Salt Lake City. The test utilizes gene expression data from 50 genes weighted together with clinical variables to generate a risk category and numerical score to assess a patient's risk of distant recurrence at ten years in postmenopausal women with node-negative (Stage I or II) or node-positive (Stage II), Hormone Receptor-Positive (HR+) breast cancer.

16 Dec 2013

Study could lead towards a personalised medicine for chemoresistant lymphomata

To date, tests have only been carried out on cells, but a piece of research conducted by the Department of Genetics at the UPV/EHU's Faculty of Medicine in collaboration with MD Anderson and the CNIO is opening up the door for the treatment of lymphoma types that have a lower survival rate. The study of the molecular characteristics of the tumours would enable molecules that are altered in a specific way to be identified and turned into new therapeutic targets that would improve the prognosis of patients with chemoresistant lymphomata.

16 Dec 2013

New discovery could help combat spread of sleeping sickness

A new discovery by scientists could help combat the spread of sleeping sickness.

15 Dec 2013

Daily exercise lessens harmful physiological effects of short-term overeating, inactivity, says study

Daily exercise lessens many of the harmful physiological effects of short-term overeating and inactivity, shows a new study [published 15 December] in The Journal of Physiology, which is well timed with the Christmas holiday approaching.

15 Dec 2013

Eleven researchers receives 2014 DeLill Nasser Award for Professional Development in Genetics

The Genetics Society of America (GSA) is pleased to announce the selection of eleven early career researchers - five graduate students and six postdoctoral researchers - as recipients of a spring 2014 DeLill Nasser Award for Professional Development in Genetics.

15 Dec 2013

Scientists reveal how two genes interact to kill broad range of cancer cells

Scientists from Virginia Commonwealth University Massey Cancer Center have revealed how two genes interact to kill a wide range of cancer cells. Originally discovered by the study's lead investigator Paul B. Fisher, M.Ph., Ph.D., the genes known as mda-7/IL-24 and SARI could potentially be harnessed to treat both primary and metastatic forms of brain, breast, colon, lung, ovary, prostate, skin and other cancers.

14 Dec 2013

Study shows effectiveness of PAM50-based Prosigna Breast Cancer Prognostic Gene Signature Assay

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced new results from a combined analysis of the Austrian Breast & Colorectal Cancer Study Group 8 (ABCSG-8) and Trans-Arimidex, Tamoxifen, Alone or in Combination (TransATAC) studies. These results, which evaluated samples from 2,137 patients, suggest that the PAM50-based Prosignaz Breast Cancer Prognostic Gene Signature Assay may help identify women with late distant recurrence after five years of endocrine treatment.

13 Dec 2013

Deep genome sequencing used to predict clinical outcomes in patients with breast cancer tumors

New research from University Hospitals (UH) Case Medical Center Seidman Cancer Center and Case Comprehensive Cancer Center at Case Western Reserve University examined how changes in the genetic composition of breast cancer tumors after brief exposure to either biologic therapy or chemotherapy can predict future clinical outcomes in patients.

13 Dec 2013

Spaceflights cause cellular-level damage and may lead to long-term vision problems

Those who travel to space are rewarded with a beautiful sight - planet Earth. But the effects of space travel on the human sense of sight aren't so beautiful. More than 30 percent of astronauts who returned from two-week space shuttle missions and 60 percent who spent six months aboard the International Space Station were diagnosed with eye problems. Two recent investigations examined mechanisms that may explain eye changes in spaceflight, help find ways to minimize this health risk to astronauts and eventually prevent and treat eye diseases on Earth.

13 Dec 2013

Genomic tests help in selecting the most effective therapy for breast cancer

Genomic tests that determine the molecular subtype of a woman's breast cancer provide a more precise prognosis and valuable guidance about the best treatment, according to new research led by Massimo Cristofanilli, M.D, Director of the Jefferson Breast Care Center at the Kimmel Cancer Center (KCC) and Thomas Jefferson University and Hospitals.

13 Dec 2013

Researchers uncover second rare genetic mutation linked to higher risk of Alzheimer's disease

A research team from The University of Nottingham has helped uncover a second rare genetic mutation which strongly increases the risk of Alzheimer's disease in later life.

13 Dec 2013

Names of 2014 Breakthrough Prize winners in Fundamental Physics and Life Sciences unveiled

The names of the 2014 Breakthrough Prize winners in Fundamental Physics and Life Sciences were unveiled at an exclusive ceremony at the NASA Ames Research Center, Mountain View, CA. At a total awarded amount of $21 million, sponsored by Sergey Brin & Anne Wojcicki, Jack Ma & Cathy Zhang, Yuri & Julia Milner and Mark Zuckerberg & Priscilla Chan, the prizes aim to celebrate scientists and generate excitement about the pursuit of science as a career.

13 Dec 2013

New treatment options for diabetic wound healing in cornea and skin

Diabetes Mellitus (DM), a metabolic disorder that affects nearly 170 million people worldwide, is characterized by chronic hyperglycemia that disrupts carbohydrate fat and protein metabolism resulting from defects in insulin secretion, insulin action or both. DM can cause long-term damage, dysfunction and even failure of various organs.

13 Dec 2013

Gene Expression Barcode 3.0 tool proves to be a vital resource for cancer research

A newly improved internet research tool is helping cancer researchers and physicians make sense out of a deluge of genetic data from nearly 100,000 patients and more than 50,000 mice.

13 Dec 2013

UCLA stem cell researchers track early development of human articular cartilage

Stem cell researchers from UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have published the first study to identify the origin cells and track the early development of human articular cartilage, providing what could be a new cell source and biological roadmap for therapies to repair cartilage defects and osteoarthritis. These revolutionary therapies could reach clinical trials within three years.

13 Dec 2013

More outreach needed for family members who carry genetic risks of cancer

A study done by researchers at Fox Chase Cancer Center shows that many relatives of patients who undergo testing for a gene linked to breast and ovarian cancers misinterpret the results, and less than half of those who could benefit from genetic testing say they plan to get tested themselves-despite the fact that knowing your genetic status may help catch the disease in its earliest stages.

13 Dec 2013

University of Colorado medical school professor uncovers variant of NKH

People from around the country and the world turn to Johan Van Hove, MD, PhD, for advice on a rare metabolic disease known as NKH, which can disrupt the body in devastating and even deadly ways. Now, Van Hove, a University of Colorado medical school professor, has identified a new disease related to NKH, a finding that resolves previously baffling cases including the death of a Colorado girl.

13 Dec 2013

Boys who grow up in two-parent homes less likely to have high blood pressure as adults

In a study of African-American men, researchers from the National Institutes of Health found that boys who grew up in two-parent homes were less likely to have high blood pressure as adults compared to those raised by a single parent. Reported in the Dec. 12, 2013, issue of the journal Hypertension, this is the first study of an African-American population to document an association between childhood family living arrangements and blood pressure.

13 Dec 2013

Genes News and Research

Scientists establish a goal of creating vaccine gene chip to speed up vaccine testing

Research findings point to possible new strategy for treating ALS

PAM50 FDA-cleared breast cancer test to be launched at ARUP Laboratories

Study could lead towards a personalised medicine for chemoresistant lymphomata

New discovery could help combat spread of sleeping sickness

Daily exercise lessens harmful physiological effects of short-term overeating, inactivity, says study

Eleven researchers receives 2014 DeLill Nasser Award for Professional Development in Genetics

Scientists reveal how two genes interact to kill broad range of cancer cells

Study shows effectiveness of PAM50-based Prosigna Breast Cancer Prognostic Gene Signature Assay

Deep genome sequencing used to predict clinical outcomes in patients with breast cancer tumors

Spaceflights cause cellular-level damage and may lead to long-term vision problems

Genomic tests help in selecting the most effective therapy for breast cancer

Researchers uncover second rare genetic mutation linked to higher risk of Alzheimer's disease

Names of 2014 Breakthrough Prize winners in Fundamental Physics and Life Sciences unveiled

New treatment options for diabetic wound healing in cornea and skin

Gene Expression Barcode 3.0 tool proves to be a vital resource for cancer research

UCLA stem cell researchers track early development of human articular cartilage

More outreach needed for family members who carry genetic risks of cancer

University of Colorado medical school professor uncovers variant of NKH

Boys who grow up in two-parent homes less likely to have high blood pressure as adults

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics