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Research proves effectiveness of vaccine against leishmaniasis

The disease is considered endemic in the south states of Mexico. A research executed in the Autonomous University of Yucatan (UADY) has successfully proved, in test animals, the effectiveness of a vaccine that immunizes the organism against leishmaniasis, an ailment transmitted through insects very similar to mosquitos and mainly presents symptoms in the skin, liver or spleen.

3 Dec 2013

Researchers find evidence that gout clusters in families

It's historically known as 'the king of diseases and the disease of kings' and was long thought to be caused by an overindulgent lifestyle, but now scientists at The University of Nottingham have confirmed that 'gout' strongly runs in families.

3 Dec 2013

IRCM researcher sheds light on inconsistencies between pharmacogenomic studies

A bioinformatics expert at the IRCM, Benjamin Haibe-Kains, recently published an article stressing the importance of standardizing drug screening studies in the prestigious scientific journal Nature. The study supports the need for further development and standardization to improve the reproducibility of drug screening studies, as they are important in identifying new therapeutic agents and their potential combinations with existing drugs.

3 Dec 2013

New genetics promises to change faulty genes of future generations by using "designer sperm”

Bethesda, MD-Get ready: The "new genetics" promises to change faulty genes of future generations by introducing new, functioning genes using "designer sperm." A new research report appearing online in The FASEB Journal, shows that introducing new genetic material via a viral vector into the sperm of mice leads to the presence and activity of those genes in the resulting embryos.

3 Dec 2013

Researchers create computer algorithm to identify specific genes involved in breast cancer growth

Researchers from the University of Alberta and Alberta Health Services have created a computer algorithm that successfully predicts whether estrogen is sending signals to cancer cells to grow into tumours in the breast. By finding this hormone receptor, known as estrogen receptor positive, physicians can prescribe anti-estrogen drug therapies, improving patient outcomes.

3 Dec 2013

Scientists explain new family of proteins that appear to play key role in cancer

Scientists have described a new family of proteins that appear to play a key role in cancer and might be targets for future cancer drugs.

3 Dec 2013

Multiplicom launches MID kit for Illumina MiSeq and MASTR kits for MODY, ADH and HCM

Multiplicom NV, a specialist in the development, production and commercialization of innovative molecular genetic tests based on massively parallel sequencing, today announces that it is launching a CE/IVD labeled MID kit for Illumina MiSeq together with three new germline mutation detection MASTRTM kits enabling the identification of individuals at risk for maturity onset diabetes of the young, autosomal dominant hypercholesterolemia, and hypertrophic cardiomyopathy.

2 Dec 2013

European Patent Office issues Notice of Grant to 22nd Century Group for NBB and A622 genes

22nd Century Group, Inc. today announced that the European Patent Office issued a Notice of Grant to the company for the NBB and A622 genes. Both genes are responsible for nicotine production in the tobacco plant.

30 Nov 2013

UC San Diego biophysicists discover how antibiotic resistance allows bacteria to multiply

Using quantitative models of bacterial growth, a team of UC San Diego biophysicists has discovered the bizarre way by which antibiotic resistance allows bacteria to multiply in the presence of antibiotics, a growing health problem in hospitals and nursing homes across the United States.

30 Nov 2013

Three Umeå University researchers selected as Wallenberg Academy Fellows

Jonathan Klaminder, Christian Hedberg and Sjoerd Wanrooij have been selected as Wallenberg Academy Fellows at Umeå University. They are awarded grants between SEK 5 and 9 million each spread over five years from the largest single private investment in supporting young researchers in Sweden.

29 Nov 2013

Male roundworms shorten the lifespan of females, say Stanford researchers

Researchers at the Stanford University School of Medicine have discovered that males of the laboratory roundworm secrete signaling molecules that significantly shorten the lifespan of the opposite sex.

29 Nov 2013

Researchers identify gene responsible for malfunctions in fear-related memory system

A study published recently in the Journal of Neuroscience points, for the first time, to the gene trkC as a factor in susceptibility to the disease. The researchers define the specific mechanism for the formation of fear memories which will help in the development of new pharmacological and cognitive treatments.

29 Nov 2013

Surgeon performs first-ever retrograde gene therapy on human heart

Ernie Lively moved to a scenic home in the mountains of Wasatch County to escape the hectic pace of Hollywood when he retired. But retirement didn't provide Lively with the active lifestyle he craved because of simple reality: His heart was failing.

28 Nov 2013

Compound extracted from wine-processed Fructus corni protects hippocampal neurons from damage

Studies have shown that Fructus corni has a protective effect on hepatocytes, and has anticancer, antioxidative, anti-inflammatory and antiseptic properties. 5-hydroxymethylfurfural, a compound extracted from wine-processed Fructus corni, has a protective effect on hippocampal neurons damaged by H2O2.

28 Nov 2013

Drugs delivered by nanoparticles hold promise for targeted treatment of many diseases, including cancer

Drugs delivered by nanoparticles hold promise for targeted treatment of many diseases, including cancer. However, the particles have to be injected into patients, which has limited their usefulness so far.

27 Nov 2013

Mutation in alpha-synuclein gene causes increased vulnerability to pesticides, leading to Parkinson's

A team of researchers has brought new clarity to the picture of how gene-environmental interactions can kill nerve cells that make dopamine. Dopamine is the neurotransmitter that sends messages to the part of the brain that controls movement and coordination.

27 Nov 2013

Implantable genetic circuit serves as early warning system for high blood-fat levels

Humankind has a weight problem - and not only in the industrialised nations, either: the growing prosperity in many Asian or Latin American countries goes hand in hand with a way of life that quite literally has hefty consequences.

27 Nov 2013

Study uncovers mechanisms that allow stem cells to keep dividing in perpetuity

The blood stem cells that live in bone marrow are at the top of a complex family tree. Such stem cells split and divide down various pathways that ultimately produce red cells, white cells and platelets. These "daughter" cells must be produced at a rate of about one million per second to constantly replenish the body's blood supply.

27 Nov 2013

Genetics and cardiovascular drugs: an interview with Nancy Lurker, CEO of PDI and Paul Kinnon, CEO of Transgenomic, Inc.

People inherit different versions of any particular gene, and some genes affect how patients process and metabolize medicines. This especially holds true for people with cardiovascular (CV) disease. They may be fast, slow or non-metabolizers and might also react badly (with serious adverse events) to certain drug therapies or not at all.

27 Nov 2013

Inhibition of complement system plays major role in xenograft rejection

Researchers at the Bellvitge Institute of Biomedical Research (IDIBELL) led by Cristina Costa from the New Therapies on Genes and Transplantation group have shown that inhibition of one of the basic components of the complement system protects chondrocytes (cartilage cells) from porcine rejection of xenotransplantation (transplantation between animals of different species).

27 Nov 2013

Genes News and Research

Research proves effectiveness of vaccine against leishmaniasis

Researchers find evidence that gout clusters in families

IRCM researcher sheds light on inconsistencies between pharmacogenomic studies

New genetics promises to change faulty genes of future generations by using "designer sperm”

Researchers create computer algorithm to identify specific genes involved in breast cancer growth

Scientists explain new family of proteins that appear to play key role in cancer

Multiplicom launches MID kit for Illumina MiSeq and MASTR kits for MODY, ADH and HCM

European Patent Office issues Notice of Grant to 22nd Century Group for NBB and A622 genes

UC San Diego biophysicists discover how antibiotic resistance allows bacteria to multiply

Three Umeå University researchers selected as Wallenberg Academy Fellows

Male roundworms shorten the lifespan of females, say Stanford researchers

Researchers identify gene responsible for malfunctions in fear-related memory system

Surgeon performs first-ever retrograde gene therapy on human heart

Compound extracted from wine-processed Fructus corni protects hippocampal neurons from damage

Drugs delivered by nanoparticles hold promise for targeted treatment of many diseases, including cancer

Mutation in alpha-synuclein gene causes increased vulnerability to pesticides, leading to Parkinson's

Implantable genetic circuit serves as early warning system for high blood-fat levels

Study uncovers mechanisms that allow stem cells to keep dividing in perpetuity

Genetics and cardiovascular drugs: an interview with Nancy Lurker, CEO of PDI and Paul Kinnon, CEO of Transgenomic, Inc.

Inhibition of complement system plays major role in xenograft rejection

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