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Targeting the brain should be the focus of ALS therapy, not just spinal cord

The brain is indeed a target for treating ALS (amyotrophic lateral sclerosis), Northwestern Medicine scientists have discovered.

4 Dec 2021

Study reveals source of the brain's resting energy drain

Pound for pound, the brain consumes vastly more energy than other organs, and, puzzlingly, it remains a fuel-guzzler even when its neurons are not firing signals called neurotransmitters to each other.

4 Dec 2021

Elevated heart rate in old age may be an independent risk factor of dementia

Having an elevated resting heart rate in old age may be an independent risk factor of dementia, according to a study at Karolinska Institutet in Sweden published in the journal Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

3 Dec 2021

HyVIS project to develop bionic synapses for retinal prostheses

HyVIS, the European project coordinated by the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology), is about to start.

3 Dec 2021

Study sheds new light on how certain neurons regulate the number of heart muscle cells

Human heart muscle cells cease to multiply after birth, making any heart injury later in life a permanent one, reducing function and leading to heart failure.

2 Dec 2021

Study documents and visualizes hearing loss-associated genes in the inner ear

Researchers from Uppsala University have been able to document and visualise hearing loss-associated genes in the human inner ear, in a unique collaboration study between otosurgeons and geneticists.

2 Dec 2021

NEI researchers identify unique population of B cells that tamps down the immune system

Researchers at the National Eye Institute (NEI) have identified, isolated, and characterized a unique population of B cells that tamps down the immune system, reducing chronic inflammation.

2 Dec 2021

Novel set of immune cells may have the opposite effect in multiple sclerosis, other brain conditions

A group of immune cells that normally protect against inflammation in the gastrointestinal tract may have the opposite effect in multiple sclerosis (MS) and other brain inflammation-related conditions, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian researchers.

1 Dec 2021

Scientists identify new genes associated with familial Meniere's disease

A team of scientists from the University of Granada (UGR) and GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research—led by Pablo Roman-Naranjo and Jose Antonio López-Escámez, researcher in charge of the Biohealth Research Institute in Granada (ibs.GRANADA)—has identified new genes associated with familial Meniere's disease.

1 Dec 2021

Researchers genetically map cell types that make up the mouse iris

Johns Hopkins Medicine researchers report they have genetically mapped the cell types that make up the mouse iris — the thin disc of pigmented tissue that, in humans, gives eyes their distinct colors.

30 Nov 2021

Breakthrough discovery paves the way for brain-like computers

Research has long strived to develop computers to work as energy efficiently as our brains. A study, led by researchers at the University of Gothenburg, has succeeded for the first time in combining a memory function with a calculation function in the same component.

30 Nov 2021

Clinical drug research for the treatment of CNS and neurological disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

29 Nov 2021

Persistent opioid use among 12% of patients after cardiac implantable electronic device procedures

About 12 percent of patients who receive implantable cardiac devices such as a pacemaker or defibrillator and fill an opioid prescription after surgery will consistently use the pain medication in the months afterward, raising the potential for addiction following these common procedures and identifying another pathway that could contribute to the national opioid crisis, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

26 Nov 2021

Minimally invasive ablation procedure offers long-term relief after knee replacement surgery

A minimally invasive ablation procedure offers long-term relief for patients who experience chronic and debilitating pain after knee replacement surgery, according to a study being presented next week at the annual meeting of the Radiological Society of North America.

24 Nov 2021

Adolescent and young adult ASD patients show changes in the brain's white matter microstructure

Researchers at Yale University analyzing specialized MRI exams found significant changes in the microstructure of the brain's white matter in adolescents and young adults with autism spectrum disorder (ASD) compared to a control group, according to research being presented next week at the annual meeting of the Radiological Society of North America.

23 Nov 2021

Study confirms safety of electroconvulsive therapy for treatment of mental conditions

The safety concerns associated with electroconvulsive therapy (ECT) are unwarranted, according to a new study in Frontiers in Psychology.

23 Nov 2021

Semiflexible optoelectrodes for high-resolution neuron readout and stimulation with low damage

The use of electrodes placed inside the brains of laboratory specimens has pushed the field of neuroscience to new findings for decades.

23 Nov 2021

GABA secreted by B-cells blunts the body's cytotoxic T-cell-based response to tumors

A group of scientists led by researchers from the RIKEN Center for Integrative Medical Sciences have discovered that B-cells, a type of immune cell, secrete the neurotransmitter GABA, and also found that the GABA secreted by the B-cells promoted the emergence of anti-inflammatory macrophages, blunting the body's cytotoxic T-cell-based response to tumors.

21 Nov 2021

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic disorder affecting children and adolescents, suggests a study in mice by scientists at the National Institutes of Health.

20 Nov 2021

ALS also causes retinal alterations, study reveals

Amyotrophic lateral sclerosis (ALS), characterized by harm to brain neurons and to the spinal cord, also affects the tissue of the retina, according to a study headed up by Universidad Complutense de Madrid.

16 Nov 2021

Nerve News and Research

Targeting the brain should be the focus of ALS therapy, not just spinal cord

Study reveals source of the brain's resting energy drain

Elevated heart rate in old age may be an independent risk factor of dementia

HyVIS project to develop bionic synapses for retinal prostheses

Study sheds new light on how certain neurons regulate the number of heart muscle cells

Study documents and visualizes hearing loss-associated genes in the inner ear

NEI researchers identify unique population of B cells that tamps down the immune system

Novel set of immune cells may have the opposite effect in multiple sclerosis, other brain conditions

Scientists identify new genes associated with familial Meniere's disease

Researchers genetically map cell types that make up the mouse iris

Breakthrough discovery paves the way for brain-like computers

Clinical drug research for the treatment of CNS and neurological disorders

Persistent opioid use among 12% of patients after cardiac implantable electronic device procedures

Minimally invasive ablation procedure offers long-term relief after knee replacement surgery

Adolescent and young adult ASD patients show changes in the brain's white matter microstructure

Study confirms safety of electroconvulsive therapy for treatment of mental conditions

Semiflexible optoelectrodes for high-resolution neuron readout and stimulation with low damage

GABA secreted by B-cells blunts the body's cytotoxic T-cell-based response to tumors

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

ALS also causes retinal alterations, study reveals

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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