Genes News and Research

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Parkinson's Institute, Population Diagnostics discover new genes relevant to Parkinson's disease

The Parkinson's Institute and Clinical Center announced today that they, in partnership with Population Diagnostics, Inc., have discovered a number of new genes relevant to the cause of Parkinson's disease.

20 Nov 2013

Staphylococcus Aureus Bacteria anticipates and turns immune defenses against the host

Around 20 percent of all humans are persistently colonized with Staphylococcus aureus bacteria, a leading cause of skin infections and one of the major sources of hospital-acquired infections, including the antibiotic-resistant strain MRSA.

20 Nov 2013

TSRI researchers solve structure of key protein in deadly, but little known virus

What began as a summer internship project designed for an undergraduate student evolved into a one-year study of one of the deadliest, but little known viruses. Researchers at The Scripps Research Institute (TSRI) have now solved the structure of a key protein in the Nipah virus, which could pave the way for the development of a much-needed antiviral drug.

20 Nov 2013

Rapid DNA biochip tests for screening disease-causing bacteria

Patients affected by a bacterial infection can usually be treated with an antibiotic. But sometimes a resistant bacterial strain is causing the infection. In a hospital setting, doctors ideally want to know if they are dealing with such bacteria and which drugs they should choose. But if the doctor runs a test it can take days to get a result. Now, a European project is paving the way for much more rapid tests using DNA biochips. The aim is to rapidly screen disease-causing bacteria using a microarray to spot which resistant genes are present in bacteria.

20 Nov 2013

NIAID awards $4.4M grant to study unknown gene function in bacteria that cause plague, brucellosis

The National Institute of Allergy and Infectious Diseases has awarded the University of Chicago $4.4 million over five years to study genes of unknown function in bacteria that cause plague and brucellosis.

20 Nov 2013

Gene-based method for selecting doses of warfarin no better than standardized dosing methods

A new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania has determined that a gene-based method for selecting patients' doses of the popular heart medication warfarin is no better than standardized dosing methods. The study was presented today at the 2013 Scientific Sessions of the American Heart Association and published simultaneously in the New England Journal of Medicine.

20 Nov 2013

Loyola University initiates clinical trial of vaccine that trains immune system to fight melanoma

Loyola University Medical Center is enrolling melanoma patients in the first clinical trial in the Midwest of an experimental vaccine that trains a patient's immune system to fight the deadly cancer.

20 Nov 2013

Study shows bacteria can passively integrate damaged DNA in their own genome

From a bacteria's perspective the environment is one big DNA waste yard. Researchers have now shown that bacteria can take up small as well as large pieces of old DNA from this scrapheap and include it in their own genome.

20 Nov 2013

Researchers report long-term benefits of gene therapy in advanced heart failure patients

Researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai reported the long-term benefits of a single dose of their gene therapy AAV1/SERCA2a in advanced heart failure patients on Nov. 19 at the American Heart Association Scientific Sessions 2013.

20 Nov 2013

Penn researchers advance towards new DNA sequencing technique using graphene nanoribbon

The instructions for building all of the body's proteins are contained in a person's DNA, a string of chemicals that, if unwound and strung end to end, would form a sentence 3 billion letters long. Each person's sentence is unique, so learning how to read gene sequences as quickly and inexpensively as possible could pave the way to countless personalized medical applications.

19 Nov 2013

Layers of skin that form first line of defence in body's fight against infection reveal secret

The layers of skin that form the first line of defence in the body's fight against infection have revealed a unanticipated secret.

19 Nov 2013

Manipulating PRH protein can help prevent cancer cells from unnecessary migration

Understanding how and why cancer cells move away from their original location is important to find ways to stop the spread of the disease. New findings, published in the Nature journal Oncogene, reveal how a protein, called 'PRH', is normally able to prevent cells from unnecessary migration. It is likely that this protein is less effective in cancer cells allowing the cells to venture away.

19 Nov 2013

Researchers find that caspase-2 gene plays important role in suppressing blood cell cancer

Adelaide researchers have found that a specific gene plays an important role in suppressing lymphoma, a type of blood cell cancer.

19 Nov 2013

Mutations affecting immune system play important role in breast cancer

Mutations in the genes that defend the body against cancer-related viruses and other infections may play a larger role in breast cancer than previously thought, according to a study at the University of Illinois at Chicago.

19 Nov 2013

Researchers solve structure of key protein in Nipah virus

What began as a summer internship project designed for an undergraduate student evolved into a one-year study of one of the deadliest, but little known viruses.

18 Nov 2013

Habitual dietary intake of monozygotic twins associated with fecal microbiota composition

The establishment of microbial populations in the gastrointestinal-tract is a complex process, involving microbial and host interactions eventually resulting in a dense and stable population.

18 Nov 2013

Researchers identify genes that put children at high risk of serious asthma attacks

An international team spearheaded by researchers from the University of Copenhagen has identified the genes that put some children at particularly high risk of serious asthma attacks, including one not previously suspected of being implicated in the disease.

18 Nov 2013

Close to 100 novel human gene regions that code for proteins may be linked to cancer

By using a new analysis method, researchers at Karolinska Institutet and Science for Life Laboratory (SciLifeLab) in Sweden have found close to one hundred novel human gene regions that code for proteins. A number of these regions are so-called pseudogenes, which may be linked to cancer.

18 Nov 2013

Researchers explore how certain molecular signaling pathways control aging across all species

Fruit flies are notoriously short-lived but scientists interested in the biology of aging in all animals have begun to understand why some fruit flies live longer than others. They have documented a direct association between insulin and life span, for example, and have observed a tradeoff between prolific reproduction and longevity. A new study, which may have broad implications across species, ties those findings more closely together by tracing an insulin signaling cascade through to protein quality control in muscle tissue and shortened life span.

18 Nov 2013

Researchers develop novel system to image worm brain activity

A research team at Worcester Polytechnic Institute and The Rockefeller University in New York has developed a novel system to image brain activity in multiple awake and unconstrained worms. The technology, which makes it possible to study the genetics and neural circuitry associated with animal behavior, can also be used as a high-throughput screening tool for drug development targeting autism, anxiety, depression, schizophrenia, and other brain disorders.

18 Nov 2013

Genes News and Research

Parkinson's Institute, Population Diagnostics discover new genes relevant to Parkinson's disease

Staphylococcus Aureus Bacteria anticipates and turns immune defenses against the host

TSRI researchers solve structure of key protein in deadly, but little known virus

Rapid DNA biochip tests for screening disease-causing bacteria

NIAID awards $4.4M grant to study unknown gene function in bacteria that cause plague, brucellosis

Gene-based method for selecting doses of warfarin no better than standardized dosing methods

Loyola University initiates clinical trial of vaccine that trains immune system to fight melanoma

Study shows bacteria can passively integrate damaged DNA in their own genome

Researchers report long-term benefits of gene therapy in advanced heart failure patients

Penn researchers advance towards new DNA sequencing technique using graphene nanoribbon

Layers of skin that form first line of defence in body's fight against infection reveal secret

Manipulating PRH protein can help prevent cancer cells from unnecessary migration

Researchers find that caspase-2 gene plays important role in suppressing blood cell cancer

Mutations affecting immune system play important role in breast cancer

Researchers solve structure of key protein in Nipah virus

Habitual dietary intake of monozygotic twins associated with fecal microbiota composition

Researchers identify genes that put children at high risk of serious asthma attacks

Close to 100 novel human gene regions that code for proteins may be linked to cancer

Researchers explore how certain molecular signaling pathways control aging across all species

Researchers develop novel system to image worm brain activity

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