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Titin gene mutations affect heart function in healthy individuals, study finds

A multinational study by researchers from the UK, Singapore and Germany has discovered that gene mutations in a protein called titin affect heart function in healthy individuals.

22 Nov 2016

Study highlights potential to develop antiviral therapies, vaccines for treating astroviruses

Human astroviruses infect nearly everyone during childhood, causing diarrhea, vomiting, and fever.

22 Nov 2016

Salk scientists discover key to amplification of ‘invader’ signals

When a receptor on the surface of a T cell -- a sentry of the human immune system -- senses a single particle from a harmful intruder, it immediately kicks the cell into action, launching a larger immune response. But exactly how the signal from a single receptor, among thousands on each T cell, can be amplified to affect a whole cell has puzzled immunologists for decades.

22 Nov 2016

Research shows cellular component may play vital role in how lung cancer spreads

A cellular component known as the Golgi apparatus may play a role in how lung cancer metastasizes, according to researchers at The University of Texas MD Anderson Cancer Center whose findings were reported in the Nov. 21 online issue of the Journal of Clinical Investigation.

21 Nov 2016

Researchers sequence genome of parasitic worm that causes river blindness

Scientists have sequenced the genome of the parasitic worm responsible for causing onchocerciasis--an eye and skin infection more commonly known as river blindness.

21 Nov 2016

Study shows new drug combination effective in treating precancerous skin lesions

A combination of two topical drugs that have been in use for years triggers a robust immune response against precancerous skin lesions, according to a new study. The research, from Washington University School of Medicine in St. Louis and Harvard Medical School, shows that the therapy activates the immune system's T cells, which then attack the abnormal skin cells.

21 Nov 2016

TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

While there have been advances in the treatment of hormone-driven breast cancer, resistance to these therapies remains a significant problem.

21 Nov 2016

Researchers identify protein that plays key role in LDL accumulation in blood vessels

A Yale-led research team identified a protein that plays an important role in the buildup of LDL cholesterol in blood vessels.

21 Nov 2016

Researchers design smart drug to treat patients with most aggressive brain cancers

Physicians and researchers at Houston Methodist Hospital have designed a new drug to treat patients with the most aggressive, incurable brain cancers.

21 Nov 2016

Results of high-impact clinical trials could improve kidney-related medical care

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented at ASN Kidney Week 2016, November 15-20 at McCormick Place in Chicago, IL.

21 Nov 2016

Diabetic patients with three major risk factors experience sharp reduction in healthy renal function

Patients with diabetes and suffering from acute kidney injury (AKI), proteinuria and uncontrolled blood sugar experience a sharp reduction in the number of years they have healthy renal function before being forced onto dialysis, according to researchers at the University of Cincinnati College of Medicine.

21 Nov 2016

New study describes role of protein that is crucial for melanoma cell survival

The main goals of the Melanoma Group at the Spanish National Cancer Research Centre are to identify biomarkers of tumour progression and to validate novel therapeutic targets in melanoma.

21 Nov 2016

Weight loss programs can help breast cancer survivors reduce risk of recurrence

Cancer experts are also discussing studies that show that weight loss programs can change the biological make-up of breast tissue cells - helping survivors reduce their cancer risk.

18 Nov 2016

Scientists uncover novel process by which APOL1 gene contributes to renal disease

A Children's National Health System research team has uncovered a novel process by which the gene APOL1 contributes to renal disease, according to a paper published November 18 in the Journal of the American Society of Nephrology.

18 Nov 2016

Scientists capture DNA intermediates that reveal how cancer evolves

Scientists from Rice University, Baylor College of Medicine and other institutions are using synthetic biology to capture elusive, short-lived snippets of DNA that healthy cells produce on their way to becoming cancerous.

18 Nov 2016

Molecules team up to maintain healthy level of fat in liver, study finds

As obesity rates rise in the United States, so does the incidence of liver diseases.

18 Nov 2016

Researchers discover protein complex that enables 'quality control' of immune T cells

The research into T cell development within an organ called the thymus revealed for the first time that a protein complex called LUBAC enables 'quality control' of the cells before they are released into the bloodstream.

18 Nov 2016

Maintaining healthy weight may be key to prevent MGUS progression to multiple myeloma

New research shows that excess weight increases the risk that a benign blood disorder will progress into multiple myeloma, a cancer of the blood.

18 Nov 2016

Study finds way to detect early signs of AD by looking at retina of patients' eyes

A new study from The University of Texas Medical Branch at Galveston offers important insight into how Alzheimer's disease begins within the brain.

18 Nov 2016

Scientists develop genetically engineered T cells with fusion inhibitor to disrupt HIV's harpoon

When HIV attacks a T cell, it attaches itself to the cell's surface and launches a "harpoon" to create an opening to enter and infect the cells.

18 Nov 2016

G Protein News and Research

Titin gene mutations affect heart function in healthy individuals, study finds

Study highlights potential to develop antiviral therapies, vaccines for treating astroviruses

Salk scientists discover key to amplification of ‘invader’ signals

Research shows cellular component may play vital role in how lung cancer spreads

Researchers sequence genome of parasitic worm that causes river blindness

Study shows new drug combination effective in treating precancerous skin lesions

TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

Researchers identify protein that plays key role in LDL accumulation in blood vessels

Researchers design smart drug to treat patients with most aggressive brain cancers

Results of high-impact clinical trials could improve kidney-related medical care

Diabetic patients with three major risk factors experience sharp reduction in healthy renal function

New study describes role of protein that is crucial for melanoma cell survival

Weight loss programs can help breast cancer survivors reduce risk of recurrence

Scientists uncover novel process by which APOL1 gene contributes to renal disease

Scientists capture DNA intermediates that reveal how cancer evolves

Molecules team up to maintain healthy level of fat in liver, study finds

Researchers discover protein complex that enables 'quality control' of immune T cells

Maintaining healthy weight may be key to prevent MGUS progression to multiple myeloma

Study finds way to detect early signs of AD by looking at retina of patients' eyes

Scientists develop genetically engineered T cells with fusion inhibitor to disrupt HIV's harpoon

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