Myocardial Infarction News and Research

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Studies use three genes to reprogram fibroblasts into myocytes

The latest research developments to reprogram scar tissue resulting from myocardial infarction (MI) into viable heart muscle cells, were presented at the Frontiers in CardioVascular Biology (FCVB) 2012 meeting, held 30 March to 1 April at the South Kensington Campus of Imperial College in London.

2 Apr 2012

Out-of-hospital use of GIK as therapy for ACS patients needs to be assessed

Patients experiencing symptoms such as chest pain who received from paramedics an intravenous solution consisting of glucose-insulin-potassium (GIK) had no reduction in the rate of progression to heart attack and no improvement in 30-day survival, although GIK was associated with a lower rate of the composite outcome of cardiac arrest or in-hospital death, according to a study appearing in JAMA.

28 Mar 2012

CRF initiates Harmonizing Outcomes with Revascularization and Stents in AMI II trial

The Cardiovascular Research Foundation (CRF) today announced the initiation of the HORIZONS-AMI II randomized trial, evaluating Promus Element platinum-chromium everolimus-eluting stents versus Omega bare-metal stents in patients with heart attack undergoing primary angioplasty with bivalirudin anticoagulation.

28 Mar 2012

Study shows safe and effective protocol for chest pain patients

Rhode Island Hospital physicians report that managing chest pain patients within an emergency department chest pain unit by both emergency medicine staff and cardiologists is safe and effective and may lower the use of stress testing.

27 Mar 2012

UAB cardiac rehab program reduces mortality among people with heart attack

After two heart attacks and 10 stents, Rick Vinson had a decision to make — do nothing and likely die from heart disease like his father or take a chance at having a long life. Vinson chose the latter. After receiving his last stent in October 2010, he entered a cardiac rehab program at the University of Alabama at Birmingham. Since then he has dropped 20 pounds, his cholesterol has dropped to 141 from 315 and his triglycerides are down to 149 from 465.

27 Mar 2012

Bolus intracoronary abciximab reduces infarct size in high-risk patients with STEMI

Administration of a bolus dose of the anticoagulant drug abciximab into the coronary artery involved in causing a certain type of heart attack among patients who were undergoing a percutaneous coronary intervention and also receiving another anticoagulant resulted in reduction in the size of damage to the heart muscle at 30 days, while a procedure that involved use of a catheter to remove the blood clot blocking that coronary artery did not produce these results, according to a study appearing in JAMA.

27 Mar 2012

Study finds imbalance between growth of PCI centers and the U.S. population

There is an imbalance between the rapid growth of cardiac catheterization laboratories, which provide percutaneous coronary intervention (PCI) procedures, relative to the growth in the overall U.S. population, as well as patients who experience an acute heart attack, or ST-elevation myocardial infarction (STEMI), according to a study presented March 25 at the 61st annual American College of Cardiology (ACC) scientific session.

27 Mar 2012

PCI may be an excellent option for STEMI patients 90 years and older

Selected patients 90 years and older who experience an acute heart attack, or ST-elevation myocardial infarction (STEMI), have reasonable outcomes with coronary stenting, and should be considered for reperfusion therapy, based on a scientific poster being presented at the 61st annual American College of Cardiology (ACC) scientific session.

26 Mar 2012

Results from Merck's vorapaxar study on cardiovascular events

Researchers today presented and published results from the TRA-2P (Thrombin-Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events) TIMI 50 study of vorapaxar, Merck's investigational anti-thrombotic medicine, in patients with a prior history of cardiovascular events or disease.

26 Mar 2012

Real-time, non-invasive test to detect heart attack

What if your doctor could tell you in real-time, with a non-invasive test as to whether or not you might be having an acute myocardial infarction (AMI) or in simpler terms, a heart attack?

23 Mar 2012

Study uses Veridex CellSearch technology to capture CECs in MI patients

Veridex, LLC today announced the publication of a new, investigational study published this week in Science Translational Medicine that lays the foundation for research that may potentially result in a blood test to determine imminent risk of heart attack within high-risk populations.

22 Mar 2012

EMS responders can play a significant role in reducing MCTB time for STEMI patients

Health care practitioners have long understood the importance of "door to balloon" time for heart attack patients-the faster they can get the patient from the door of the hospital to a catheterization lab to open a clogged artery, the better the patient will do.

22 Mar 2012

Depression increases risk of death in PCI patients

Depression increases the risk of death in patients who have a coronary stent implanted. After seven years of follow up, depressed patients were 1.5 times more likely to have died than non-depressed patients. The findings were independent of age, gender, clinical characteristics, anxiety and the distressed (Type D) personality.

16 Mar 2012

Light-to-moderate drinking may reduce risk of stroke in women

Light-to-moderate alcohol consumption has been consistently associated with lower risk of heart disease, but data for stroke are less certain, especially among women.

16 Mar 2012

Higher spending on effective procedures and services leads to better patient outcomes

Among hospitals in Ontario, Canada, those with higher levels of spending, which included higher intensity nursing and greater use of specialists and procedures, had an associated lower rate of deaths, hospital readmissions, and better quality of care for severely ill hospitalized patients, according to a study in the March 14 issue of JAMA.

14 Mar 2012

Cenderitide may preserve cardiac function after heart attack

The National Heart, Lung and Blood Institute (NHLBI), a division of the National Institutes of Health (NIH), has awarded a $2.5 million grant to Mayo Clinic's Cardiorenal Research Laboratory to conduct a highly innovative research project, "Cardiovascular Peptides and Myocardial Infarction."

6 Mar 2012

Polymer-based medical implants can produce harmful free radicals

A polymer is a mesh of chains, which slowly break over time due to the pressure from ordinary wear and tear. When a polymer is squeezed, the pressure breaks chemical bonds and produces free radicals: ions with unpaired electrons, full of untapped energy. These molecules are responsible for aging, DNA damage and cancer in the human body.

3 Mar 2012

Initial stent implantation does not appear to improve outcomes for patients with stable CAD

A meta-analysis of eight previously published clinical trials suggests that initial stent implantation for patients with stable coronary artery disease is not associated with improved outcomes compared with initial medical therapy for prevention of death, nonfatal heart attacks, unplanned revascularization or angina, according to a study published in the Feb. 27 Archives of Internal Medicine, one of the JAMA/Archives journals.

28 Feb 2012

Research roundup: Hospital medication errors; Key Medicaid issues in 2014

Use Of Preventive Services Could Be Better Aligned With Clinical Recommendations -- This report looks at Medicare patients' use of eight specific preventive services, which have "the potential to improve health outcomes and lower health care expenditures," according to the authors. Use of cardiovascular and cervical cancer screenings "generally aligned with clinical recommendations, ... but use of other cancer screenings" did not.

24 Feb 2012

FDA approves Boston Scientific's ION and TAXUS Liberte paclitaxel-eluting stents

Boston Scientific Corporation's ION Paclitaxel-Eluting Platinum Chromium Coronary Stent System and TAXUS Liberte Paclitaxel-Eluting Coronary Stent System have received U.S. Food and Drug Administration (FDA) approval for use in patients experiencing an acute myocardial infarction (AMI), or heart attack.

23 Feb 2012