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In vivo imaging of α-synuclein aggregates in the brains of living patients with multiple system atrophy

α-synuclein is a neuronal protein involved in functions like vesicle trafficking and neurotransmitter release. It is typically found in abundance in a healthy brain.

30 Aug 2022

Using human tissue models to improve treatment and diagnosis of heart attacks

A heart attack, or myocardial infarction, is one of the leading causes of mortality worldwide, resulting in 18 million deaths per year.

30 Aug 2022

Novel mechanism identified that SARS-CoV-2 uses to suppress antiviral responses to make the cell more permissive to infection

Researchers assessed the impact of SARS-CoV-2 ORF-6 on innate immune signaling.

30 Aug 2022

The effects of amino acid substitutions on the affinity of the SARS-CoV-2 spike RBD to the human receptor hACE2

Researchers performed a structural bioinformatics analysis to evaluate the binding energy of the SARS-CoV-2 Omicron variants of concern spike protein receptor-binding domain to human angiotensin-converting enzyme 2 receptor compared to other VOCs.

30 Aug 2022

Study finds strong evidence for the ability of SARS-CoV-2 to infect human sperm in vitro

Researchers explored the molecular and cellular mechanisms of SARS-CoV-2 infection.

30 Aug 2022

Discovery paves the way for specific therapies for common form of childhood brain and spine tumor

A study conducted by researchers in Brazil, Australia, Austria and the United States has made significant discoveries about a type of pediatric cancer with no approved drugs for treatment and with a low survival rate.

29 Aug 2022

The clinical and virological outcomes associated with molnupiravir or nirmatrelvir–ritonavir use in hospitalized patients with mild-to-moderate COVID-19

Researchers investigated whether early treatment with oral antivirals prevented all-cause mortality in hospitalized patients infected with SARS-CoV-2 new variant of concern Omicron BA.2 subvariant.

29 Aug 2022

The effectiveness of nirmatrelvir in preventing severe COVID-19 outcomes during the Omicron surge

Researchers assessed the clinical efficacy of nirmatrelvir in preventing severe COVID-19 in Israel during the Omicron wave.

29 Aug 2022

A leather-based in vitro model for determining the effect of cosmetics on skin microbes

A recent study discusses the development of a leather-based in vitro model due to its close resemblance to human skin.

28 Aug 2022

School-aged children can successfully self-swab to obtain COVID-19 test specimen, study finds

A new study that could have immediate implications for COVID-19 testing in schools found that with age-appropriate instructions, school-aged children can successfully use a nasal swab to obtain their own COVID-19 test specimen.

26 Aug 2022

The risk of adverse reactions when herbal medications are taken with cancer drugs

A new study discusses phytovigilance initiatives based on the real-world use of herbal drugs in cancer along with conventional chemotherapy.

24 Aug 2022

Tiny sensor can simultaneously measure electrical and mechanical cellular responses in cardiac cells

Using a suspended nanowire, a University of Massachusetts research team has, for the first time, created a tiny sensor that can simultaneously measure electrical and mechanical cellular responses in cardiac tissue, work promising for cardiac disease studies, drug testing and regenerative medicine.

24 Aug 2022

Targeting Na+/K+ ATPase alpha 1 proteins could help identify novel therapies for blood clots, thrombosis

Targeting Na+/K+ ATPase alpha 1 (ATP1A1) subunit proteins could help identify novel therapies for addressing blood clots and thrombosis, according to a new study by Marshall University researchers.

24 Aug 2022

Vertical transfer of humoral immune protection after maternal SARS-CoV-2 vaccination

In a new study, researchers assessed the presence, durability, and neutralization potency of immunoglobulin G and IgA antibodies against SARS-CoV-2 in breastfeeding infant stools, maternal plasma, and breast milk following maternal COVID-19 vaccination.

24 Aug 2022

Biological effects of nanoplastics in paints

A recent study analyzed paint composition and its biological properties, as paints release polymers and particles into the environment.

24 Aug 2022

Wyss Institute's DNA nanotechnology-driven SPEAR protein-detection technology licensed to Spear Bio

Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Spear Bio, Inc.announced that the Institute's DNA nanotechnology-driven ultrasensitive SPEAR protein-detection technology has been licensed to the newly formed Boston-based startup.

23 Aug 2022

in vitro News and Research

In vivo imaging of α-synuclein aggregates in the brains of living patients with multiple system atrophy

Using human tissue models to improve treatment and diagnosis of heart attacks

Novel mechanism identified that SARS-CoV-2 uses to suppress antiviral responses to make the cell more permissive to infection

The effects of amino acid substitutions on the affinity of the SARS-CoV-2 spike RBD to the human receptor hACE2

Study finds strong evidence for the ability of SARS-CoV-2 to infect human sperm in vitro

Discovery paves the way for specific therapies for common form of childhood brain and spine tumor

The clinical and virological outcomes associated with molnupiravir or nirmatrelvir–ritonavir use in hospitalized patients with mild-to-moderate COVID-19

The effectiveness of nirmatrelvir in preventing severe COVID-19 outcomes during the Omicron surge

A leather-based in vitro model for determining the effect of cosmetics on skin microbes

School-aged children can successfully self-swab to obtain COVID-19 test specimen, study finds

The risk of adverse reactions when herbal medications are taken with cancer drugs

Tiny sensor can simultaneously measure electrical and mechanical cellular responses in cardiac cells

Targeting Na+/K+ ATPase alpha 1 proteins could help identify novel therapies for blood clots, thrombosis

Vertical transfer of humoral immune protection after maternal SARS-CoV-2 vaccination

Biological effects of nanoplastics in paints

Wyss Institute's DNA nanotechnology-driven SPEAR protein-detection technology licensed to Spear Bio

Epistasis leads to the reduction in genetic barrier to COVID-19 neutralizing antibody escape

DNA origami as an alternative platform to display the RBD of SARS-CoV-2

What risk factors are associated with post-acute sequelae of SARS-CoV-2?

Association between infant intestinal microbiome and respiratory diseases of childhood

Driving innovation in drug discovery with in vitro biology solutions eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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