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Mount Sinai School of Medicine, Alnylam collaborate to develop microRNA-based attenuated influenza viruses

Mount Sinai School of Medicine has completed an exclusive option agreement with Alnylam Pharmaceuticals, Inc. a leading RNAi therapeutics company, for intellectual property related to RNAi applications in vaccine development. These new applications of RNAi technology define opportunities for the advancement of novel vaccines in infectious disease.

18 Jun 2010

Maternal, infant ART drives down mother-to-child HIV transmission through breast-feeding, studies show

According to two new studies, "giving pregnant and nursing women triple antiretroviral drug therapy, or treating breast-fed infants with an antiretroviral medication, can dramatically cut transmission rates, enabling moms to both breast-feed and to protect nearly all children from infection," HealthDay News/Bloomberg Businessweek reports (Goodwin, 6/16).

18 Jun 2010

Baylor University researchers awarded grant to research and test new compounds for cancer

The National Institutes of Health has awarded two Baylor University researchers a $1.46 million grant to research and test new compounds that could help fight cancerous tumors.

18 Jun 2010

Drug makers face tightened regulations by FDA and less clout at medical meetings

The Washington Post: "The Food and Drug Administration this week began posting online the results of safety evaluations of recently approved drugs and vaccines. The action follows a law enacted in 2007 that requires the agency to provide more safety information to consumers and health professionals. The evaluations must be conducted 18 months after a new drug comes on the market.

18 Jun 2010

Elderly people in sub-Saharan Africa remain neglected as a result of AIDS epidemic: Researchers

The rise in AIDS death rates in sub-Saharan Africa has led to a burgeoning new category of neglected individuals - nearly a million orphaned elderly, or older adults living alone without the benefit of any caregivers, Stanford University School of Medicine researchers have found.

18 Jun 2010

Paternal involvement in pregnancy reduces infant deaths

Studies have shown fathers who are active in their children's upbringing can significantly benefit their children's early development, academic achievement and well being. Now, a new study by University of South Florida researchers suggests that a father's involvement before his child is born may play an important role in preventing death during the first year of life - particularly if the infant is black.

18 Jun 2010

Loss of Manhattan hospital crowds other ERs; Utah discourages Medicaid patients from unnecessary ER visits

"Emergency rooms in downtown Manhattan have become more crowded since St. Vincent's Hospital closed in April, but ambulances are getting patients into the remaining ERs faster than they did when the 161-year-old Greenwich Village hospital was open." Bellevue Hospital Center, Beth Israel Medical Center, New York Downtown Hospital and New York University Langone Medical Center are the "four downtown ERs left to pick up the slack" and have experienced increases in patient visits in May compared with 2008 levels.

18 Jun 2010

Possible mechanism identified for how lithium treats bipolar disorder

Lithium has been established for more than 50 years as one of the most effective treatments for manic depression, clinically termed bipolar disorder. However, scientists have never been entirely sure exactly why it is beneficial.

18 Jun 2010

Obama thanks nurses for health law support, nurse practitioners push role

President Obama Wednesday thanked the American Nurses Association for supporting the health reform effort, The Associated Press reports. "Obama said nurses are the 'beating heart' of the health care system. … The Obama administration on Wednesday also announced new funding (Today's Daily Report includes summaries of coverage related to this announcement.) to help educate and train full-time nurses" (Simmons, 6/17).

18 Jun 2010

Neonatal diarrhea may lead to life threatening dehydration and malnutrition: Research

Diarrhea represents a major condition responsible for pediatric mortality worldwide. The onset of neonatal diarrhea may rapidly lead to life threatening dehydration and malnutrition. Clinical and epidemiologic studies defining severity and etiology are needed in order to improve diagnostic and therapeutic approaches for the management of neonatal diarrhea.

18 Jun 2010

Experts discuss G8 aid commitments

Economist Jeffrey Sachs said Wednesday that the G8 could endanger its credibility if leaders fail to fulfill several "broken multi-billion-dollar pledges" aimed at helping the developing world, Canwest News Service/Vancouver Sun reports.

18 Jun 2010

Republicans, Obama administration spar over health overhaul

A Heritage Foundation-affiliated conservative advocacy group, Heritage Action, will begin targeting lawmakers "at home in their districts" who fail to support the GOP-led efforts to repeal the overhaul with political ads and other tactics, according to The Hill, which quoted Michael Needham, the just-launched Action group's CEO "The effects of Obamacare are being felt more and more every day.

18 Jun 2010

Postmenopausal women who have low calcium intake show higher risk of developing osteoporosis, hypertension

Italian postmenopausal women who have a low calcium intake show a higher risk of developing both osteoporosis and hypertension (a chronic medical condition in which arterial blood pressure is elevated) than those who consume higher levels of calcium according to research presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy.

18 Jun 2010

First patient dosed in AR-42 Phase I/IIa clinical study at OSUCCC-James in adult patients with blood cancer

Arno Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on developing oncology therapeutics, today announced the dosing of the first patient in an investigator sponsored Phase I/IIa clinical study of AR-42 (formerly OSU-HDAC42) at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James) in adult patients with relapsed or refractory multiple myeloma (MM), chronic lymphocytic leukemia (CLL) or lymphoma.

18 Jun 2010

Justice Department asks court to throw out states' lawsuit challenging health overhaul

The Associated Press reports that the Justice Department filed a motion in Florida late Wednesday asking a "federal judge to dismiss a lawsuit by 20 states challenging President Barack Obama's health care overhaul." The states are arguing that the federal government cannot require individuals to buy health insurance, a key provision of the new health law.

18 Jun 2010

HHS announces $250 million in federal funding to boost primary care providers

The Washington Post: "In an attempt to address a national shortage of health-care workers, Health and Human Services Secretary Kathleen Sebelius said Wednesday that the federal government will spend $250 million in programs to increase the number of doctors, nurses and other care providers. The money ... includes $168 million to train 500 new primary-care physicians over the next five years, $30 million to encourage 600 nursing students to attend school full-time and complete their education, and $32 million to create 600 new physician assistants."

18 Jun 2010

Huntington online bill payment created to support Pelotonia bike tour for cancer research

In another bankwide effort to support the Pelotonia bike tour for cancer research, Huntington has created a way for consumers to donate to the cure for cancer through Huntington online bill payment.

18 Jun 2010

FDA approves new indication for Tasigna in treatment of rare blood cancer

The U.S. Food and Drug Administration today approved a new indication for Tasigna (nilotinib) for the treatment of a rare blood cancer when it is first diagnosed. The cancer, called Philadelphia chromosome positive chronic phase chronic myeloid leukemia (Ph+ CP-CML), is a slowly progressing blood and bone marrow disease linked to a genetic abnormality.

18 Jun 2010

GOP extenders proposal fails; Dems still seek to lower cost on their bill

Senate Republicans failed Thursday to replace a broad Democratic jobless benefits bill, which includes a provision to stop a pending 21 percent cut in Medicare reimbursements to doctors. The Republican option failed in a 57-41 vote, The Wall Street Journal reports.

18 Jun 2010

Health IT implementation plan: 'Bold incrementalism'

Farzad Mostashari, a senior official in the government's health IT office, said in a speech Tuesday that the strategy for implementing federal ehealth efforts is one of "bold incrementalism," Modern Healthcare reports. Mostashari listed as an example the Office of the National Coordinator for Health IT's "approach to the health information exchange.

18 Jun 2010

Research News and Research

Mount Sinai School of Medicine, Alnylam collaborate to develop microRNA-based attenuated influenza viruses

Maternal, infant ART drives down mother-to-child HIV transmission through breast-feeding, studies show

Baylor University researchers awarded grant to research and test new compounds for cancer

Drug makers face tightened regulations by FDA and less clout at medical meetings

Elderly people in sub-Saharan Africa remain neglected as a result of AIDS epidemic: Researchers

Paternal involvement in pregnancy reduces infant deaths

Loss of Manhattan hospital crowds other ERs; Utah discourages Medicaid patients from unnecessary ER visits

Possible mechanism identified for how lithium treats bipolar disorder

Obama thanks nurses for health law support, nurse practitioners push role

Neonatal diarrhea may lead to life threatening dehydration and malnutrition: Research

Experts discuss G8 aid commitments

Republicans, Obama administration spar over health overhaul

Postmenopausal women who have low calcium intake show higher risk of developing osteoporosis, hypertension

First patient dosed in AR-42 Phase I/IIa clinical study at OSUCCC-James in adult patients with blood cancer

Justice Department asks court to throw out states' lawsuit challenging health overhaul

HHS announces $250 million in federal funding to boost primary care providers

Huntington online bill payment created to support Pelotonia bike tour for cancer research

FDA approves new indication for Tasigna in treatment of rare blood cancer

GOP extenders proposal fails; Dems still seek to lower cost on their bill

Health IT implementation plan: 'Bold incrementalism'

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