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Caltech researchers map out pathways of neurons responsible for Parkinson's motor impairments

Because billions of neurons are packed into our brain, the neuronal circuits that are responsible for controlling our behaviors are by necessity highly intermingled. This tangled web makes it complicated for scientists to determine exactly which circuits do what. Now, using two laboratory techniques pioneered in part at Caltech, Caltech researchers have mapped out the pathways of a set of neurons responsible for the kinds of motor impairments--such as difficulty walking--found in patients with Parkinson's disease.

21 Apr 2016

Hot packs or hot-water immersion may be effective in treating jellyfish stings

A recent study by researchers at the University of Hawaiʻi at Mānoa, published this month in the journal Toxins, may finally put to rest the ongoing debate about whether to use cold or heat to treat jellyfish stings. Their systematic and critical review provides overwhelming evidence that clinical outcomes from all kinds of jellyfish stings are improved following treatment with hot packs or hot-water immersion.

21 Apr 2016

Using Proteomics to Understand Alzheimer’s: An Interview with Dr Renã Robinson

In our bioanalytical mass spectrometry lab we use proteomics techniques to try to understand more about Alzheimer's disease. The primary thrust of our research is that we're interested in understanding the changes that take place outside of the brain and how those correlate with what's taking place inside the brain

From Pittcon 21 Apr 2016

New diagnostic approach may help physicians more efficiently screen for dementia

A tiered diagnostic approach that incorporates clinical, imaging and laboratory data may help physicians more efficiently screen for neurodegenerative disorders such as dementia, according to the consensus of a multi-disciplinary panel of experts.

From Quest Diagnostics 21 Apr 2016

Angola' health officials extend vaccination campaign for yellow fever to Huambo and Benguela provinces

As Angola grapples with its worst yellow fever outbreak in decades, the Ministry of Health, with the support of the World Health Organization and partners have extended the vaccination campaign beyond the capital Luanda into Huambo and Benguela – 2 of the other 5 provinces reporting local transmission.

21 Apr 2016

LAP defects may lead to lupus-like autoimmune disorder

A casual observation about size differences in mice has led to the discovery that defects in a process for digesting dead cells called LC3-associated phagocytosis (LAP) may lead to a lupus-like autoimmune disorder. St. Jude Children's Research Hospital scientists led the research, which appears as an advance online publication today in the scientific journal Nature.

21 Apr 2016

New mouse model to aid in development of antiviral compounds, vaccines against Zika virus

Researchers at the University of Wisconsin-Madison School of Veterinary Medicine have developed one of the first mouse models for the study of Zika virus. The model will allow researchers to better understand how the virus causes disease and aid in the development of antiviral compounds and vaccines.

20 Apr 2016

Endurance running training increases bone density

Spanish researchers have analysed the effect of endurance running training on the stiffness index, a variable that is directly related to bone quality. The results confirm that the greater the race distance that is trained, the better; this can be used, therefore, to prevent the progressive decline in bone mineral density that occurs with age.

20 Apr 2016

New study suggests re-evaluation of long-held method to predict effectiveness of seasonal influenza vaccine

The long-held approach to predicting seasonal influenza vaccine effectiveness may need to be revisited, new research suggests. Currently, seasonal flu vaccines are designed to induce high levels of protective antibodies against hemagglutinin (HA), a protein found on the surface of the influenza virus that enables the virus to enter a human cell and initiate infection.

20 Apr 2016

Daily dark chocolate consumption could help improve athletic performance

Dark chocolate has already been hailed for its positive effects on cardiovascular health - and now a study undertaken at London's Kingston University has found the tasty treat could help give sports enthusiasts an extra edge in their fitness training.

20 Apr 2016

$New refractive index detector with a very wide dynamic range from KNAUER$

New refractive index detector with a very wide dynamic range from KNAUER

At Analytica 2016, the trade show for the laboratory field taking place in Munich from May 10th to 13th, KNAUER will be introducing a newly developed refractive index (RI) detector with most up-to-date features.

From KNAUER Wissenschaftliche Geräte GmbH 20 Apr 2016

Drexel study provides new insight into future treatment of breathing disorders

Bringing a steady supply of fresh air to the lungs can seem like a simple task, but breathing is a careful orchestration of brain and body.

20 Apr 2016

NObreath®: the essential tool for World Asthma Day

Asthma UK found 120,000 asthma sufferers at risk from wrongly prescribed medication, while NICE found 30% of people with asthma suspected to be misdiagnosed.

From Bedfont® Scientific Ltd 20 Apr 2016

Scientists identify underlying cause of immune suppression in people with high level spinal cord injuries

Scientists report in Nature Neuroscience they have identified an underlying cause of dangerous immune suppression in people with high level spinal cord injuries and they propose a possible treatment.

19 Apr 2016

Tecnalia's transparent bioadjesive gel could treat diabetic foot ulcers

Tecnalia's Pharmaceutical Development laboratory conducts the selection of the candidate polymers and topical antiseptics necessary to obtain a stable, safe and effective formula in the form of a transparent bioadjesive gel specific for the treatment of diabetic foot ulcers.

19 Apr 2016

New therapy strategy for liver disease shows initial measureable success with norUrso

The new therapy strategy for primary sclerosing cholangitis, a liver disease that at present still cannot be cured with medication, shows initial measureable success with the nor-ursodeoxycholic acid (norUrso).

19 Apr 2016

Newly discovered player in epigenetic regulation closely linked to known cancer promoters

If genes form the body's blueprint, then the layer of epigenetics decides which parts of the plan get built. Unfortunately, many cancers hijack epigenetics to modulate the expression of genes, thus promoting cancer growth and survival.

19 Apr 2016

Researchers identify biological pathway that explains why current asthma therapies fail in many cases

Asthma is an enormous public health problem that continues to grow larger, in part because scientists don't fully understand how it is caused. Existing therapies don't cure the disease and often don't even significantly alleviate the symptoms. Now, scientists from the Perelman School of Medicine at the University of Pennsylvania and Rutgers University have identified a biological pathway that potentially explains why current asthma therapies don't work well in many cases—and might be targeted to help those patients.

19 Apr 2016

Penn researchers report results of CAR therapy trial in brain cancer patients

Immune cells engineered to seek out and attack a type of deadly brain cancer known as glioblastoma (GBM) were found to have an acceptable safety profile and successfully migrate to and infiltrate tumors, researchers from Penn Medicine and Harvard University reported at the AACR Annual Meeting 2016.

19 Apr 2016

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Cancer cells often devise ways to survive even in the presence of toxic chemotherapy. Now, a research team led by investigators at Beth Israel Deaconess Medical Center has found a way to attack a process that tumor cells use to escape the effects of standard cancer drugs. The discovery is published online today in the journal Nature Cell Biology.

19 Apr 2016

Laboratory News and Research

Caltech researchers map out pathways of neurons responsible for Parkinson's motor impairments

Hot packs or hot-water immersion may be effective in treating jellyfish stings

Using Proteomics to Understand Alzheimer’s: An Interview with Dr Renã Robinson

New diagnostic approach may help physicians more efficiently screen for dementia

Angola' health officials extend vaccination campaign for yellow fever to Huambo and Benguela provinces

LAP defects may lead to lupus-like autoimmune disorder

New mouse model to aid in development of antiviral compounds, vaccines against Zika virus

Endurance running training increases bone density

New study suggests re-evaluation of long-held method to predict effectiveness of seasonal influenza vaccine

Daily dark chocolate consumption could help improve athletic performance

New refractive index detector with a very wide dynamic range from KNAUER

Drexel study provides new insight into future treatment of breathing disorders

NObreath®: the essential tool for World Asthma Day

Scientists identify underlying cause of immune suppression in people with high level spinal cord injuries

Tecnalia's transparent bioadjesive gel could treat diabetic foot ulcers

New therapy strategy for liver disease shows initial measureable success with norUrso

Newly discovered player in epigenetic regulation closely linked to known cancer promoters

Researchers identify biological pathway that explains why current asthma therapies fail in many cases

Penn researchers report results of CAR therapy trial in brain cancer patients

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

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