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UCMR researchers discover compounds that can attenuate virulence of Listeria monocytogenes

Scientists at Umea Centre for Microbial Research have discovered chemical compounds which are able to attenuate the virulence of the bacterial human pathogen Listeria monocytogenes. Their findings are published today in the high impact journal Cell Chemical Biology.

19 Mar 2016

Manipulation of NAD could lead to potential therapy for acute kidney injury

Approximately one out of five hospitalized adults and one out of three hospitalized children worldwide experience acute kidney injury, the sudden loss of kidney function. Many different factors, including surgery, chemotherapy or shock, can lead to acute kidney injury, but exactly why the kidneys are so vulnerable to these and other stressors has not been well understood.

19 Mar 2016

Aesculap plans to develop neurostimulators for lowering high blood pressure

The Tuttlingen medical technology company Aesculap AG has founded the Freiburg startup neuroloop GmbH in cooperation with the University of Freiburg and the Freiburg University Medical Center. Building on research work from a team led by Prof. Dr. Thomas Stieglitz at the university's Department of Microsystems Engineering (IMTEK) and a research group at the university medical center, the company plans to develop neurostimulators that will be capable among other things of lowering high blood pressure.

18 Mar 2016

Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

In a report on the so-called REMEMBER (Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment) study -- a 10-nation, randomized clinical trial of adult outpatients -- investigators concluded that there was no added benefit of using four drugs for TB over just using one drug, isoniazid, to save lives in people with advanced HIV/AIDS.

18 Mar 2016

Treatment guidelines need to be changed for rare, genetic form of diabetes, study suggests

Patients with a rare, genetic form of diabetes often are misdiagnosed as having type 2 diabetes because the two share symptoms.

18 Mar 2016

BioAgilytix announces acquisition of IPM Biotech

BioAgilytix, a leading provider of contract bioanalytical testing services specializing in large molecule bioanalysis, has announced the acquisition of IPM Biotech, a German-based bioanalytical contract research laboratory renowned for its expertise in large molecule bioanalysis, particularly in the area of immunogenicity.

18 Mar 2016

UNIGE researchers identify new recessive disease

The objective of genetic medicine is to analyze all the genes that make up the human genome, in order to identify as many genetic diseases as possible. Indeed, each gene variation has the potential to trigger specific defects. Among all genetic conditions, diseases known as "recessive" occur only when both the father and the mother are healthy carriers of the same defective gene which can be passed down to their children.

18 Mar 2016

USF receives $9 million NIH grant to study unique treatment for age-related hearing loss

Researchers in the University of South Florida's Global Center for Hearing and Speech Research, recognized as the world's top research center for age-related hearing loss, have received a five-year, $9 million grant from the National Institutes of Health to study two unique ways to treat age-related hearing loss (ARHL).

17 Mar 2016

Molecular basis for tongue cancer progression: an interview with Dr Simona Principe

Head and neck cancers (HNC) are the sixth most common cancers worldwide, with approximately 600,000 new cases diagnosed every year.

From Beckman Coulter Life Sciences - Centrifugation 17 Mar 2016

Automated techniques could dramatically accelerate antimicrobial discovery

The antimicrobial arsenal that we count on to save millions of lives each year is alarmingly thin--and these microbes are rapidly evolving resistance to our weapons. But help may be on the way: In a study posted in the AMB Express, researchers from the National Institute of Standards and Technology show that automated techniques commonly used to screen new drugs for mammalian cell toxicity could also dramatically speed up the challenging task of antimicrobial discovery.

17 Mar 2016

Panasonic introduces new MCO-170M multi gas incubators to optimise cell culture efficiency and productivity

Panasonic’s new MCO-170M multi gas incubators provide outstanding quality and performance alongside advanced O2 and CO2 control to maximise cell culture efficiency and optimise results and reproducibility.

From PHC Europe B.V. 17 Mar 2016

Johns Hopkins scientists develop antibody to curb lung tumor cell growth, breast cancer metastasis

Johns Hopkins scientists report they have developed an antibody against a specific cellular gateway that suppresses lung tumor cell growth and breast cancer metastasis in transplanted tumor experiments in mice, according to a new study published in the February issue of Nature Communications.

17 Mar 2016

Homeostasis may have allowed first living cells to maintain internal environment

A Massachusetts General Hospital research team investigating how the earliest stages of life might have developed has discovered a way the first living cells could have met a key challenge -- maintaining a constant internal environment, a process called homeostasis, even when external conditions change.

17 Mar 2016

Scientists find evidence that amyloid fibrils adopt several distinct architectures in human, animal tissues

Formation of amyloid fibrils is a characteristic feature of neurogenerative diseases like Alzheimer's. As published in the journal Angewandte Chemie, German and American scientists have found evidence that these fibrils adopt several distinct three-dimensional architectures in real patient and animal tissues.

16 Mar 2016

Research confirms potential use of iron oxide nanoparticles in biomedical applications

Iron oxides are widespread in nature and can be readily synthesized in the laboratory. Among them, hematite, magnetite and maghemite nanoparticles have particularly promising properties for biomedical applications.

16 Mar 2016

Porvair Sciences to demonstrate sample preparation products for Lab Automation facilities at ELRIG Symposium

Porvair Sciences has announced it has chosen the ELRIG Symposium in Rennes, France (3-4th May 2016) to demonstrate its latest products that enable Lab Automation facilities to optimise sample preparation and improve productivity.

From Porvair Sciences Limited 16 Mar 2016

New Postnova Analytics office opens in UK

Postnova Analytics, the leading international supplier of Field-Flow Fractionation (FFF) systems, has opened a dedicated office to enhance local support for its growing base of UK customers.

From Postnova Analytics 16 Mar 2016

Caloric restriction leads to fatale weakening of the immune system

It's already well known that a diet may have a life-extending effect. Researchers from Leibniz Institute on Aging - Fritz Lipmann Institute in Jena, Germany, now showed that besides improving the functionality of stem cells in mice, a caloric restriction also leads to a fatale weakening of their immune system - counteracting the life-lengthening effect of a diet.

16 Mar 2016

Many kidney transplant patients may benefit from lower-than-standard dose of CNIs

The kidney is the most commonly transplanted organ in the United States, with more than 17,000 transplants performed each year. Following kidney transplant, patients are routinely placed on a regimen of immunosuppressant medications to prevent organ rejection, which often includes calcineurin inhibitors (CNIs) as the backbone medication of this regimen.

16 Mar 2016

Researchers explore problem of obesity from the inside out

In the last 40 years, obesity has more than doubled around the world. In the United States, the average American is more than 24 pounds heavier today than in 1960. Researchers at Baylor College of Medicine, Technion-Israel Institute of Technology and the University of Washington are studying the problem of obesity from the inside out.

16 Mar 2016

Laboratory News and Research

UCMR researchers discover compounds that can attenuate virulence of Listeria monocytogenes

Manipulation of NAD could lead to potential therapy for acute kidney injury

Aesculap plans to develop neurostimulators for lowering high blood pressure

Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

Treatment guidelines need to be changed for rare, genetic form of diabetes, study suggests

BioAgilytix announces acquisition of IPM Biotech

UNIGE researchers identify new recessive disease

USF receives $9 million NIH grant to study unique treatment for age-related hearing loss

Molecular basis for tongue cancer progression: an interview with Dr Simona Principe

Automated techniques could dramatically accelerate antimicrobial discovery

Panasonic introduces new MCO-170M multi gas incubators to optimise cell culture efficiency and productivity

Johns Hopkins scientists develop antibody to curb lung tumor cell growth, breast cancer metastasis

Homeostasis may have allowed first living cells to maintain internal environment

Scientists find evidence that amyloid fibrils adopt several distinct architectures in human, animal tissues

Research confirms potential use of iron oxide nanoparticles in biomedical applications

Porvair Sciences to demonstrate sample preparation products for Lab Automation facilities at ELRIG Symposium

New Postnova Analytics office opens in UK

Caloric restriction leads to fatale weakening of the immune system

Many kidney transplant patients may benefit from lower-than-standard dose of CNIs

Researchers explore problem of obesity from the inside out

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