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Intestinal hormones hold promise for halting liver scarring

Hormone therapy may be associated with menopause and fertility treatment, but now an SDU-led research team reports that certain intestinal hormones seem to have a beneficial effect on the processes behind the formation of scar tissue in the liver (liver fibrosis).

16 Nov 2023

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

The R136S genetic mutation protected against apolipoprotein E4 (APOE4)-induced late-onset Alzheimer’s disease (LOAD).

16 Nov 2023

Scientists develop an improved method to study Parkinson's disease in the lab

A recent study published in Progress in Neurobiology and led by researchers at the University of Arizona College of Medicine – Tucson has developed an improved method to study Parkinson's disease in the lab.

15 Nov 2023

Electroconvulsive therapy alleviates depression symptoms by increasing aperiodic activity

Electroconvulsive therapy (ECT), formerly known as electroshock therapy, involves inducing a brief seizure in the brain using controlled doses of electricity.

15 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Study sheds new light on key cellular processes involved in Parkinson's disease progression

In a study published in Nature Communications, investigators at Beth Israel Deaconess Medical Center (BIDMC) shed new light on key cellular processes involved in the progression of Parkinson's disease (PD).

15 Nov 2023

Longitudinal study elucidates mechanisms driving progression of neurodegenerative disorders

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 21, entitled, "Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model."

15 Nov 2023

New diagnostic workflow improves detection of 5q-spinal muscular atrophy

5q-spinal muscular atrophy (5q-SMA) is one of the more common types of spinal muscular atrophy (SMA) affecting around one in ten thousand individuals worldwide.

15 Nov 2023

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Whether USP30 inhibition can serve as a disease-modifying therapy for Parkinson's disease (PD).

15 Nov 2023

New research explores the unique effects of ADHD medications on Drosophila brain cells

The effect of two drugs used for the treatment of attention-deficit/hyperactivity disorder.

15 Nov 2023

Microglia found to play crucial role in early human brain development

An international team of scientists has uncovered the vital role of microglia, the immune cells in the brain that acts as its dedicated defense team, in early human brain development.

14 Nov 2023

Brain-inspired computing system achieves high accuracy in handwritten digit recognition

An experimental computing system physically modeled after the biological brain "learned" to identify handwritten numbers with an overall accuracy of 93.4%. The key innovation in the experiment was a new training algorithm that gave the system continuous information about its success at the task in real time while it learned.

13 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

Early life stress circumstances alter more genes in the brain than head injuries

A surprising thing happened when researchers began exploring whether early-life stress compounds the effects of a childhood head injury on health and behavior later in life: In an animal study, stress changed the activation level of many more genes in the brain than were changed by a bump to the head.

13 Nov 2023

UCI researchers discover gene critical for muscle repair

University of California, Irvine researchers have identified a gene expressed during regeneration that is critical for muscle repair.

12 Nov 2023

DZNE neuroscientist receives grant to study link between neurodegenerative diseases and mental health

Neurodegenerative diseases like Alzheimer's and Parkinson's can be associated to depression and anxiety. Dr. Sabine Krabbe, a neuroscientist at DZNE's Bonn site, is receiving 1.2 million US dollars from the Chan Zuckerberg Initiative to understand the mechanisms involved in the onset of these syndromes.

10 Nov 2023

New insights into migraine etiology: the role of hepatocyte growth factor

The causal links between pro-inflammatory cytokine expression and migraine.

10 Nov 2023

Study reveals early role of SYNGAP1 gene in brain development

The gene SYNGAP1, the variants of which are top risk factors for Autism Spectrum Disorder (ASD), has previously unappreciated effects on the developing brain, according to a new study published in Nature Neuroscience.

9 Nov 2023

How do sex hormones and birth control affect brain fear circuits?

Researchers explores how oral contraceptive pill use interacts with the current hormonal status to affect the fear circuit structure within the brain.

9 Nov 2023

Study unravels molecular basis of chronic pain transition

Researchers from the Center for Translational Immunology at University Medical Center Utrecht (the Netherlands) have identified that a transient inflammatory pain causes mitochondrial and redox changes in sensory neurons that persist beyond pain resolution.

8 Nov 2023

Neurons News and Research

Intestinal hormones hold promise for halting liver scarring

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

Scientists develop an improved method to study Parkinson's disease in the lab

Electroconvulsive therapy alleviates depression symptoms by increasing aperiodic activity

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study sheds new light on key cellular processes involved in Parkinson's disease progression

Longitudinal study elucidates mechanisms driving progression of neurodegenerative disorders

New diagnostic workflow improves detection of 5q-spinal muscular atrophy

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

New research explores the unique effects of ADHD medications on Drosophila brain cells

Microglia found to play crucial role in early human brain development

Brain-inspired computing system achieves high accuracy in handwritten digit recognition

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Early life stress circumstances alter more genes in the brain than head injuries

UCI researchers discover gene critical for muscle repair

DZNE neuroscientist receives grant to study link between neurodegenerative diseases and mental health

New insights into migraine etiology: the role of hepatocyte growth factor

Study reveals early role of SYNGAP1 gene in brain development

How do sex hormones and birth control affect brain fear circuits?

Study unravels molecular basis of chronic pain transition

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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