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Long COVID in children: A closer look reveals lasting impacts

A comprehensive review in Pediatrics highlights the significant impact of post-acute sequelae of SARS-CoV-2 (PASC) in children, revealing a wide range of long-term symptoms and the need for further research on its prevalence, risk factors, and mechanisms.

11 Feb 2024

Drug repurposing study finds lonafarnib effective against RSV

A study in Nature Communications identifies lonafarnib from the ReFRAME drug-repurposing library as a potent inhibitor of the RSV fusion protein, showing promise in reducing RSV infection in vitro and in vivo.

11 Feb 2024

Understanding the virological properties of SARS-CoV-2 variant JN.1

Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed a worldwide threat.

9 Feb 2024

COVID-19 linked to higher dementia risk in older adults, study finds

Research indicates a potential link between COVID-19 and an increased risk of new-onset dementia in adults over 60, with the risk being similar to that from other respiratory infections.

9 Feb 2024

AI's ability to detect COVID-19 from coughs faces real-world challenges

A Nature Machine Intelligence study reveals that while AI classifiers can predict COVID-19 from audio recordings, their effectiveness diminishes when accounting for confounding factors, highlighting the challenges in applying AI diagnostics in real-world settings.

8 Feb 2024

Never-before-documented genetic disorder causes rare lung disease

The macrophage is one of the body's most important inhabitants. Meaning "big eater" in Greek, this immune cell consumes and digests problematic elements from microbes and cancer cells to dust and debris.

8 Feb 2024

Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance."

8 Feb 2024

Study tracks health and quality of life in chronically critically ill COVID-19 patients months after hospital discharge

Researchers investigated chronic critical illness in COVID-19 survivors who sought ICU admission and were on mechanical ventilation due to severe infection by SARS-CoV-2.

8 Feb 2024

Study explores traditional Atlantic diets as a potential solution for diet-related diseases and environmental sustainability

Researchers from Spain investigated the effect of a traditional Atlantic diet on health and the environment.

8 Feb 2024

Study tracks long COVID's shifting course in general population

Long COVID trajectories in a general population cohort show variable recovery patterns, with a portion of patients experiencing improvement, deterioration, or stable symptoms over time.

7 Feb 2024

Cirrhosis patients face mixed infection outcomes amid pandemic healthcare shifts

The COVID-19 pandemic's influence on healthcare systems led to mixed outcomes for patients with cirrhosis, showing stable infection rates but a rise in multi-drug resistant organism (MDRO) infections.

7 Feb 2024

Hunters key to early detection of zoonotic diseases, study finds

Experimental games reveal hunters' vital role in zoonotic disease surveillance through community-based reporting, underscoring the need for increased participation and understanding of reporting incentives.

7 Feb 2024

Snacking on pistachios may combat metabolic syndrome risk without weight gain

More than half of Americans do not currently meet the daily recommendation of 5–7 ounce equivalents of nuts and seeds per week.

7 Feb 2024

New review: 1.6% of women and girls have debilitating Premenstrual Dysphoric Disorder

Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Disorder (PMDD), according to a new review of global studies.

7 Feb 2024

Prior Zika infection ups risk of severe dengue, study finds

A study led by Brazilian researchers shows that people who have had zika run a higher risk of subsequently having severe dengue and being hospitalized.

7 Feb 2024

Study reveals high insomnia rates in non-hospitalized COVID-19 survivors

Researchers investigated insomnia prevalence and its association with anxiety and depression in the non-hospitalized COVID-19-recovered community.

7 Feb 2024

World-first discovery offers potential cure for lupus

Australian researchers have worked out how to fix a defect that causes lupus, and hope their world-first discovery will offer effective long-term treatment.

6 Feb 2024

New cell therapy shows promise for critically ill COVID-19 patients with ARDS

Promising trial results indicate that a new type of cell therapy could improve the prognosis of those who are critically ill with acute respiratory distress syndrome (ARDS) resulting from severe Covid-19.

6 Feb 2024

Single-cell study reveals clues to epigenetic drug response in Myelodysplastic Syndrome

Researchers from the Josep Carreras Leukaemia Research Institute, spearheaded by the Cancer Epigenetics group led by Dr. Manel Esteller, described the effects of chemotherapy at the single cell resolution in the bone marrow of Myelodysplastic Syndrome patients.

6 Feb 2024

How is long-COVID different from other post-viral infection syndromes?

The symptoms, illness duration, long-term clinical traits, and possible healthcare burden of post-viral conditions in children and adolescents under 20 years.

6 Feb 2024