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First Edition: May 4, 2010

Today's headlines include stories about parts of the new health reform law dealing with long-term care, high risk insurance pools and early retiree health insurance.

4 May 2010

Celsion reports $4.6 million net loss from operations for first-quarter 2010

Celsion Corporation, a leading oncology drug development company, announced today financial results for the first quarter ended March 31, 2010 and addressed the progression of the clinical trials of ThermoDox®, Celsion's heat activated liposomal encapsulation of doxorubicin. ThermoDox® is currently being evaluated in the Phase III HEAT trial for the treatment of hepatocellular carcinoma (HCC) and in a Phase I/II trial for patients with recurrent chest wall breast cancer.

4 May 2010

Positive results from Phase 2 clinical trial of TAKSTA in patients with ABSSSI

Cempra Pharmaceuticals today announced positive results from its Phase 2 clinical trial evaluating the efficacy and tolerability of the novel front loading dosing regimen of TAKSTA (CEM-102, sodium fusidate), the company's oral, anti-methicillin-resistant Staphylococcus aureus antibiotic.

4 May 2010

Personalized vaccine processed using tumor tissue promising for brain tumor treatment

Each day in the United States, 482 people are diagnosed with a brain tumor. For these 482 people, not many treatments exist. With the current treatments available, only 5% of those diagnosed with a Glioblastoma Multiform will survive more than 5 years. Only two new treatments have been approved by the FDA in the past two decades.

4 May 2010

New study finds stereotypies in more than 60% of orphaned or abandoned children

Stereotypies -- repetitive behaviors such as rocking, flapping, spinning objects and head-banging – are commonly seen in people with autism or mental retardation. They can also be acquired by children exposed to severe neglect and deprivation, along with declines in IQ, mental health and language.

4 May 2010

Pay-for-performance programs could end up widening medical disparities: RAND study

Rewarding primary care physicians for providing better care to patients could end up widening medical disparities experienced by poorer people and those belonging to racial and ethnic minorities, according to a new RAND Corporation study.

4 May 2010

Cardiovascular specialists demonstrate effectiveness of using stents to repair aortas

A UC Davis team of cardiovascular specialists has demonstrated the effectiveness of using stents -- as compared to traditional open-chest surgery -- to repair aortas that are torn as the result of accidents. The researchers will present their findings at the American Association for Thoracic Surgery Aortic Symposium 2010, which takes place April 29-30 in New York City.

4 May 2010

Karolinska Institutet researchers discover new control mechanism in immune system

Researchers at the Swedish medical university Karolinska Institutet have discovered a new control mechanism in our immune system. The discovery is of potential significance to the treatment of serious diseases such as MS (multiple sclerosis), rheumatoid arthritis, and SLE (Systemic lupus erythematosus).

4 May 2010

Pilot pneumonia-prevention program reduces postoperative pneumonia in hospital surgical ward: Research

The results of new research results published in the April issue of the Journal of the American College of Surgeons show that a pilot pneumonia-prevention program significantly reduced postoperative pneumonia in a hospital surgical ward.

4 May 2010

Merck reports non-GAAP EPS of $0.83 for first-quarter 2010

Merck & Co., Inc. today announced financial results for the first quarter of 2010. The company reported non-GAAP (generally accepted accounting principles) earnings per share (EPS) for the first quarter of $0.83, which excludes purchase accounting adjustments, merger-related expenses and restructuring costs, as well as a tax charge related to the recently enacted health care reform legislation. First-quarter GAAP EPS was $0.09.

4 May 2010

JNM supplement examines advances in cardiovascular molecular imaging

The Journal of Nuclear Medicine -the top-rated medical imaging journal worldwide-has published Multimodality Molecular Imaging of the Cardiovascular System, presenting the state of the art of cardiovascular molecular imaging and discussing opportunities and challenges in advancing cardiovascular molecular imaging to clinical practice.

4 May 2010

MicroStockProfit.com releases investment report on Vical

MicroStockProfit.com announces an investment report featuring Vical Inc. The report includes financial, comparative and investment analyses, and industry information you need to know to make an educated investment decision.

4 May 2010

Vanda reports total revenue of $12.4 million for first-quarter 2010

Vanda Pharmaceuticals Inc., a biopharmaceutical company focused on the development and commercialization of clinical-stage products for central nervous system disorders, today announced financial and operational results for the first quarter ended March 31, 2010.

4 May 2010

FDA grants market clearance for Illumina's BeadXpress system for multiplex genetic analysis

Illumina, Inc. today announced that the U.S. Food and Drug Administration has granted 510(k) market clearance for the company's BeadXpress system for multiplex genetic analysis.

From Illumina, Inc. 4 May 2010

Isolated microalgal strain produces significant amounts of DGLA that helps reduce risk for heart attacks

Ben-Gurion University of the Negev (BGU) researchers have isolated a microalgal strain which produces large amounts of a polyunsaturated fatty acid that could reduce blood pressure, chronic inflammation and blood cholesterol level, reducing the risk for heart attacks.

4 May 2010

Alnylam Biotherapeutics presents new data on RNAi technologies at Cell Culture Engineering XII

Alnylam Biotherapeutics, a division of Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today the presentation of new data at the Cell Culture Engineering XII conference held in Alberta, Canada from April 25 - 30, 2010. Alnylam Biotherapeutics was formed by Alnylam to develop RNAi technologies for application in manufacturing processes for biotherapeutic products, including recombinant proteins and monoclonal antibodies.

4 May 2010

Immune system responds aggressively when looking at sick people

Just seeing someone who looks sick is enough to make your immune system work harder, according to a new study in which volunteers looked at pictures of sick people. This may help fight off pathogens, says Mark Schaller from the University of British Columbia who conducted the research. "It seems like it's probably good for the immune system to be responding especially aggressively at times when it looks like you are likely to be coming into contact with something that might make you sick."

4 May 2010

UCLM researcher explores employment status of HIV-positive individuals in Spain

Juan Oliva, a researcher at the University of Castilla-La Mancha explores the relationship between the employment status of Human Immunodeficiency Virus -positive individuals and socioeconomic characteristics in Spain between 2001 and 2004. The study finds that gender is a "statistically significant" variable when predicting employment status.

4 May 2010

Shorter shifts for endoscopists positively influence polyp detection rates

A shorter daily shift schedule for endoscopists, the physicians who perform colonoscopies, avoids a decrease in the polyp detection rate as the day progresses, research from Mayo Clinic indicates. The findings, which have implications for endoscopist scheduling, were presented by Mayo Clinic investigators today at Digestive Disease Week 2010, (http://www.ddw.org/wmspage.cfm?parm1=679) the annual meeting of the American Gastroenterological Association.

4 May 2010

Hartford Foundation awards $800,000 grant for training in geriatric social work

The prestigious Hartford Doctoral Fellows and Hartford Faculty Scholars programs have awarded $800,000 in combined new grants to ten researchers in the field of geriatric social work.

4 May 2010

Research News and Research

First Edition: May 4, 2010

Celsion reports $4.6 million net loss from operations for first-quarter 2010

Positive results from Phase 2 clinical trial of TAKSTA in patients with ABSSSI

Personalized vaccine processed using tumor tissue promising for brain tumor treatment

New study finds stereotypies in more than 60% of orphaned or abandoned children

Pay-for-performance programs could end up widening medical disparities: RAND study

Cardiovascular specialists demonstrate effectiveness of using stents to repair aortas

Karolinska Institutet researchers discover new control mechanism in immune system

Pilot pneumonia-prevention program reduces postoperative pneumonia in hospital surgical ward: Research

Merck reports non-GAAP EPS of $0.83 for first-quarter 2010

JNM supplement examines advances in cardiovascular molecular imaging

MicroStockProfit.com releases investment report on Vical

Vanda reports total revenue of $12.4 million for first-quarter 2010

FDA grants market clearance for Illumina's BeadXpress system for multiplex genetic analysis

Isolated microalgal strain produces significant amounts of DGLA that helps reduce risk for heart attacks

Alnylam Biotherapeutics presents new data on RNAi technologies at Cell Culture Engineering XII

Immune system responds aggressively when looking at sick people

UCLM researcher explores employment status of HIV-positive individuals in Spain

Shorter shifts for endoscopists positively influence polyp detection rates

Hartford Foundation awards $800,000 grant for training in geriatric social work

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